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RFWD2 抗体

(Ring Finger and WD Repeat Domain 2, E3 Ubiquitin Protein Ligase (RFWD2))
E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin- conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Involved in JUN ubiquitination and degradation. Directly involved in p53 (TP53) ubiquitination and degradation, thereby abolishing p53-dependent transcription and apoptosis. Ubiquitinates p53 independently of MDM2 or RCHY1. Probably mediates E3 ubiquitin ligase activity by functioning as the essential RING domain subunit of larger E3 complexes. In contrast, it does not constitute the catalytic RING subunit in the DCX DET1-COP1 complex that negatively regulates JUN, the ubiquitin ligase activity being mediated by RBX1 (By similarity).
RFWD2 抗体  (AA 632-731) RFWD2 抗体  (AA 632-731) RFWD2 抗体 (AA 632-731) (ABIN566254)

RFWD2 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 1E4 unconjugated

RFWD2 抗体  (Internal Region) RFWD2 抗体  (Internal Region) RFWD2 抗体 (Internal Region) (ABIN6259497)

RFWD2 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated

RFWD2 抗体 RFWD2 抗体 RFWD2 抗体 (ABIN7180869)

RFWD2 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated

RFWD2 抗体 by 适用

Find RFWD2 抗体 for a variety of species such as anti-Human RFWD2, anti-Mouse RFWD2, anti-Rat RFWD2. The species listed below are among those available. Click on a link to go to the corresponding products.

RFWD2 抗体 by 应用范围

Find RFWD2 抗体 validated for a specific application such as WB, ELISA, FACS, IP. Some of the available applications are listed below. Click on a link to go to the corresponding products.

RFWD2 抗体 by 抗体来源

Find RFWD2 抗体 with a specific 抗体来源. The 抗体来源 listed below are among those available. Click on a link to go to the corresponding products.

RFWD2 抗体 by 抗原表位

Find RFWD2 抗体 with a specific epitope. The epitopes listed below are among those available. Click on a link to go to the corresponding products.

RFWD2 抗体 by 克隆形成能力

Find available monoclonal or polyclonal RFWD2 抗体. Click on a link to go to the corresponding products.

RFWD2 抗体 by 克隆

Find RFWD2 抗体 with a specific 克隆. The 克隆 listed below are among those available. Click on a link to go to the corresponding products.

RFWD2 抗体 by 标记

Find RFWD2 抗体 with a specific conjugate such as Biotin, APC, FITC. The conjugates listed below are among those available. Click on a link to go to the corresponding products.

Popular RFWD2 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, ELISA, IF
Validations
  • (6)
Cat. No. ABIN566254
Quantity 100 μg
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, ELISA, IHC, IF, ICC
Validations
  • (3)
Cat. No. ABIN6259497
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA
Validations
  • (1)
Cat. No. ABIN7180869
Quantity 100 μg
Datasheet Datasheet
Reactivity Human, Mouse
Application WB, ELISA
Validations
  • (1)
Cat. No. ABIN3184044
Quantity 100 μL
Datasheet Datasheet
Reactivity Bat, Cow, Dog, Guinea Pig, Horse, Human, Monkey, Mouse, Pig, Rabbit
Application WB
Validations
  • (1)
Cat. No. ABIN6747213
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC
Validations
  • (1)
Cat. No. ABIN6146897
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB
Validations
  • (3)
  • (1)
Cat. No. ABIN1881747
Quantity 400 μL
Datasheet Datasheet
Reactivity Human
Application WB, FACS
Validations
  • (2)
Cat. No. ABIN655275
Quantity 400 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA
Validations
Cat. No. ABIN7180870
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, ELISA
Validations
Cat. No. ABIN7184760
Quantity 100 μg
Datasheet Datasheet
Reactivity Human, Mouse
Application WB, ELISA
Validations
Cat. No. ABIN6283346
Quantity 50 μL
Datasheet Datasheet
Reactivity Human, Mouse
Application WB, ELISA
Validations
Cat. No. ABIN6284679
Quantity 50 μL
Datasheet Datasheet
Reactivity Human, Mouse
Application WB, ELISA
Validations
Cat. No. ABIN6287994
Quantity 50 μL
Datasheet Datasheet
Reactivity Human
Application IP
Validations
Cat. No. ABIN7451219
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB
Validations
Cat. No. ABIN1805629
Quantity 400 μL
Datasheet Datasheet

Latest Publications for our RFWD2 抗体

Liang, Wang, Mao, Hu, Dong, Zhang, Wang, Bi: "Involvement of COP1 in ethylene- and light-regulated hypocotyl elongation." in: Planta, Vol. 236, Issue 6, pp. 1791-802, (2012) (PubMed).

Shimada, Miyagawa, Kawashima, Tanaka, Honda, Honda, Tokunaga: "An approach based on a genome-wide association study reveals candidate loci for narcolepsy." in: Human genetics, Vol. 128, Issue 4, pp. 433-41, (2010) (PubMed).

Li, Ohshiro, Reddy, Pakala, Lee, Zhang, Rayala, Kumar: "E3 ubiquitin ligase COP1 regulates the stability and functions of MTA1." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 106, Issue 41, pp. 17493-8, (2009) (PubMed).

Kato, Ding, Pisck, Jhala, Du: "COP1 functions as a FoxO1 ubiquitin E3 ligase to regulate FoxO1-mediated gene expression." in: The Journal of biological chemistry, Vol. 283, Issue 51, pp. 35464-73, (2008) (PubMed).

Aliases for RFWD2 抗体

ring finger and WD repeat domain 2 (RFWD2) 抗体
ring finger and WD repeat domain 2 (Rfwd2) 抗体
ring finger and WD repeat domain 2, E3 ubiquitin protein ligase (rfwd2) 抗体
ring finger and WD repeat domain 2, E3 ubiquitin protein ligase L homeolog (rfwd2.L) 抗体
ring finger and WD repeat domain 2 (rfwd2) 抗体
AI316802 抗体
C80879 抗体
COP1 抗体
Cop1 抗体
cop1 抗体
RFWD2 抗体
RGD1304773 抗体
RNF200 抗体
rnf200 抗体
zgc:163067 抗体
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