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RFX5 抗体

(Regulatory Factor X 5 (RFX5))
A lack of MHC-II expression results in a severe immunodeficiency syndrome called MHC-II deficiency, or the bare lymphocyte syndrome (BLS\; MIM 209920). At least 4 complementation groups have been identified in B-cell lines established from patients with BLS. The molecular defects in complementation groups B, C, and D all lead to a deficiency in RFX, a nuclear protein complex that binds to the X box of MHC-II promoters. The lack of RFX binding activity in complementation group C results from mutations in the RFX5 gene encoding the 75-kD subunit of RFX (Steimle et al., 1995). RFX5 is the fifth member of the growing family of DNA-binding proteins sharing a novel and highly characteristic DNA-binding domain called the RFX motif. Multiple alternatively spliced transcript variants have been found but the full-length natures of only two have been determined. [provided by RefSeq, Jul 2008].
RFX5 抗体  (AA 32-0) RFX5 抗体  (AA 32-0) RFX5 抗体 (AA 32-0) (ABIN106544)

RFX5 适用: 人 WB, GS 宿主: 兔 Polyclonal unconjugated

RFX5 抗体  (AA 1-616) RFX5 抗体  (AA 1-616) RFX5 抗体 (AA 1-616) (ABIN948403)

RFX5 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated

RFX5 抗体  (AA 367-616) RFX5 抗体  (AA 367-616) RFX5 抗体 (AA 367-616) (ABIN7150384)

RFX5 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated

RFX5 抗体 by Grade

Find RFX5 抗体 with a specific Grade. The Grade listed below are among those available. Click on a link to go to the corresponding products.

RFX5 抗体 by 适用

Find RFX5 抗体 for a variety of species such as anti-Human RFX5, anti-Mouse RFX5, anti-Rat RFX5. The species listed below are among those available. Click on a link to go to the corresponding products.

RFX5 抗体 by 应用范围

Find RFX5 抗体 validated for a specific application such as WB, ELISA, IP, IF. Some of the available applications are listed below. Click on a link to go to the corresponding products.

RFX5 抗体 by 抗体来源

Find RFX5 抗体 with a specific 抗体来源. The 抗体来源 listed below are among those available. Click on a link to go to the corresponding products.

RFX5 抗体 by 抗原表位

Find RFX5 抗体 with a specific epitope. The epitopes listed below are among those available. Click on a link to go to the corresponding products.

RFX5 抗体 by 克隆形成能力

Find available monoclonal or polyclonal RFX5 抗体. Click on a link to go to the corresponding products.

RFX5 抗体 by 克隆

Find RFX5 抗体 with a specific 克隆. The 克隆 listed below are among those available. Click on a link to go to the corresponding products.

RFX5 抗体 by 标记

Find RFX5 抗体 with a specific conjugate such as APC, Biotin, FITC. The conjugates listed below are among those available. Click on a link to go to the corresponding products.

Popular RFX5 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, GS
Validations
  • (3)
  • (2)
Cat. No. ABIN106544
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, IF
Validations
  • (3)
Cat. No. ABIN948403
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Application ELISA, IHC
Validations
  • (2)
Cat. No. ABIN7150384
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IP
Validations
  • (2)
Cat. No. ABIN948404
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA
Validations
  • (2)
Cat. No. ABIN519761
Quantity 100 μg
Datasheet Datasheet
Reactivity Human, Mouse
Application WB, ELISA
Validations
  • (2)
Cat. No. ABIN1590073
Quantity 100 μg
Datasheet Datasheet
Reactivity Mouse, Rat
Application WB
Validations
  • (1)
Cat. No. ABIN7075399
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB
Validations
  • (1)
Cat. No. ABIN106545
Quantity 100 μg
Datasheet Datasheet
Reactivity Dog, Human, Monkey, Pig, Rabbit
Application WB
Validations
  • (1)
Cat. No. ABIN203226
Quantity 100 μL
Datasheet Datasheet
Reactivity Guinea Pig, Horse, Human, Monkey, Mouse, Rat
Application WB
Validations
  • (1)
Cat. No. ABIN6737810
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application ELISA
Validations
Cat. No. ABIN7095106
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IP
Validations
Cat. No. ABIN7449604
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB
Validations
Cat. No. ABIN106546
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, IHC, IF
Validations
Cat. No. ABIN6775903
Quantity 100 μL
Datasheet Datasheet
Reactivity
Application
Validations
Cat. No. ABIN965402
Quantity 1 kit
Datasheet Datasheet

Latest Publications for our RFX5 抗体

Yoshimura: "Increased error-free DNA repair gene expression through reprogramming in human iPS cells." in: Regenerative therapy, Vol. 11, pp. 101-105, (2019) (PubMed).

Zhao, Xie, Liao, Zhang, Cao, Fei, Wang, Wei, Shao, Chen: "The transcription factor RFX5 is a transcriptional activator of the TPP1 gene in hepatocellular carcinoma." in: Oncology reports, Vol. 37, Issue 1, pp. 289-296, (2017) (PubMed).

Beaulieu, Leon Machado, Ethier, Gaudreau, Steimle: "Degradation, Promoter Recruitment and Transactivation Mediated by the Extreme N-Terminus of MHC Class II Transactivator CIITA Isoform III." in: PLoS ONE, Vol. 11, Issue 2, pp. e0148753, (2016) (PubMed).

Dille, Kleinschnitz, Kontchou, Nölke, Häcker: "In contrast to Chlamydia trachomatis, Waddlia chondrophila grows in human cells without inhibiting apoptosis, fragmenting the Golgi apparatus, or diverting post-Golgi sphingomyelin transport." in: Infection and immunity, Vol. 83, Issue 8, pp. 3268-80, (2015) (PubMed).

Ulbricht, Alzrigat, Horch, Reuter, von Mikecz, Steimle, Schmitt, Krämer, Stamminger, Hemmerich: "PML promotes MHC class II gene expression by stabilizing the class II transactivator." in: The Journal of cell biology, Vol. 199, Issue 1, pp. 49-63, (2012) (PubMed).

Kong, Fang, Li, Fang, Xu: "HDAC2 deacetylates class II transactivator and suppresses its activity in macrophages and smooth muscle cells." in: Journal of molecular and cellular cardiology, Vol. 46, Issue 3, pp. 292-9, (2009) (PubMed).

Chen, Chai, Hart, Zhong: "Identifying catalytic residues in CPAF, a Chlamydia-secreted protease." in: Archives of biochemistry and biophysics, Vol. 485, Issue 1, pp. 16-23, (2009) (PubMed).

Xu, Sengupta, Seto, Smith: "Regulatory factor for X-box family proteins differentially interact with histone deacetylases to repress collagen alpha2(I) gene (COL1A2) expression." in: The Journal of biological chemistry, Vol. 281, Issue 14, pp. 9260-70, (2006) (PubMed).

Aliases for RFX5 抗体

regulatory factor X5 (RFX5) 抗体
regulatory factor X, 5 (influences HLA class II expression) (Rfx5) 抗体
regulatory factor X5 (Rfx5) 抗体
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