anti-Rac GTPase Activating Protein 1 (RACGAP1) 抗体

The protein encoded by RACGAP1 belongs to the GTPase-activating protein (GAP) family. 再加上,我们可以发RACGAP1 试剂盒 (20)RACGAP1 蛋白 (7)和数多这个蛋白质的别的产品。

列出全部抗体 基因 基因ID UniProt
RACGAP1 29127 Q9H0H5
RACGAP1 26934 Q9WVM1
RACGAP1 315298  

antibodies-online.cn销售最多的anti-RACGAP1 抗体

Showing 10 out of 125 products:

产品编号 适用 宿主 标记 应用范围 图像 规格 供应商 交付 价格 详细
Cow 非结合性 WB WB Suggested Anti-RACGAP1 Antibody Titration: 1.25ug/mlELISA Titer: 1:1562500Positive Control: HepG2 cell lysate 100 μL Log in to see 24至29个工作日
非结合性 FACS, IF, IHC (p), WB Confocal immunofluorescent analysis of RACGAP1 Antibody (N-term)(ABIN655408) with MCF-7 cell followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green).DAPI was used to stain the cell nuclear (blue). 400 μL Log in to see 5至8个工作日
非结合性 EIA, FACS, IF, IHC (p), WB Flow Cytometric analysis of MCF-7 cells using RACGAP1 Antibody (N-term) Cat.-No AP53556PU-N (right histogram) compared to a Negative Control cell (left histogram). FITC-conjugated Goat-anti-Rabbit secondary antibodies were used for the analysis. Confocal immunofluorescent analysis of RACGAP1 Antibody (N-term) Cat.-No AP53556PU-N with MCF-7 cell followed by Alexa Fluor 488-conjugated Goat anti-Rabbit lgG (green).DAPI was used to stain the cell nuclear (blue). 0.4 mL Log in to see 29至35个工作日
山羊 非结合性 IHC, ELISA, WB ABIN184690 staining (0.2µg/ml) of Human Testis lysate (RIPA buffer, 30µg total protein per lane). Primary incubated for 1 hour. Detected by western blot using chemiluminescence. ABIN184690 (1µg/ml) staining of paraffin embedded Human Testis. Microwaved antigen retrieval with Tris/EDTA buffer pH9, HRP-staining. 100 μg Log in to see 24至29个工作日
Cow 非结合性 WB Host: Rabbit  Target Name: Racgap1  Sample Tissue: Rat Stomach lysates  Antibody Dilution: 1.0 µg/mL 100 μL Log in to see 24至29个工作日
小鼠 非结合性 WB RACGAP1 monoclonal antibody (M01), clone 1G6. Western Blot analysis of RACGAP1 expression in Jurkat. 0.1 mg Log in to see 11至15个工作日
Cow 山羊 非结合性 EIA, IHC (p), WB   0.1 mg Log in to see 30至37个工作日
山羊 非结合性 IHC (p), IHC, ELISA, WB ABIN257840 staining of paraffin embedded Human Testis showing A) Epithelial cells of the epididymis and B) Some leydig cells. Microwaved antigen retrieval with A)Tris/EDTA buffer pH9 at 3?g/ml or B)Citrate buffer pH6 at 10ug/ml., HRP-staining. 0.1 mg Log in to see 25至31个工作日
小鼠 非结合性 ELISA, WB Immunoperoxidase of monoclonal antibody to RACGAP1 on formalin-fixed paraffin-embedded human testis. [antibody concentration 1 ug/ml] Detection limit for recombinant GST tagged RACGAP1 is approximately 0.3ng/ml as a capture antibody. 100 μg Log in to see 29至34个工作日
非结合性 IF, IHC (p), WB Immunohistochemistry analyzes of MgcRacGAP antibody in paraffin-embedded human brain tissue. Western blot analysis of MgcRacGAP antibody in extracts from COS7 cells. 0.1 mg Log in to see 29至35个工作日

通过反应活性、应用领域、克隆类型和共轭标记 RACGAP1 抗体

特性 应用范围 宿主 克隆类型 标记
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引用最多的anti-RACGAP1 抗体

  1. Human Monoclonal RACGAP1 Primary Antibody for WB - ABIN395200 : Bailey, Xie, Do, Montpetit, Diaz, Mohan, Keavney, Yusuf, Gerstein, Engert, Anand: Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study. in Diabetes Care 2010 (PubMed)
    Show all 5 references for 395200

  2. Human Monoclonal RACGAP1 Primary Antibody for ELISA, WB - ABIN565414 : Wolfe, Takaki, Petronczki, Glotzer: Polo-like kinase 1 directs assembly of the HsCyk-4 RhoGAP/Ect2 RhoGEF complex to initiate cleavage furrow formation. in PLoS biology 2009 (PubMed)
    Show all 4 references for 565414

  3. Human Polyclonal RACGAP1 Primary Antibody for EIA, FACS - ABIN954428 : Talmud, Drenos, Shah, Shah, Palmen, Verzilli, Gaunt, Pallas, Lovering, Li, Casas, Sofat, Kumari, Rodriguez, Johnson, Newhouse, Dominiczak, Samani, Caulfield, Sever, Stanton, Shields, Padmanabhan et al.: Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip. ... in American journal of human genetics 2009 (PubMed)
    Show all 2 references for 954428

  4. Human Polyclonal RACGAP1 Primary Antibody for IHC (p), IHC - ABIN257840 : Reibel, Dorseuil, Stancou, Bertoglio, Gacon: A hemopoietic specific gene encoding a small GTP binding protein is overexpressed during T cell activation. in Biochemical and biophysical research communications 1991 (PubMed)

  5. Cow (Bovine) Polyclonal RACGAP1 Primary Antibody for WB - ABIN2777488 : Niiya, Xie, Lee, Inoue, Miki: Inhibition of cyclin-dependent kinase 1 induces cytokinesis without chromosome segregation in an ECT2 and MgcRacGAP-dependent manner. in The Journal of biological chemistry 2005 (PubMed)

  6. Human Polyclonal RACGAP1 Primary Antibody for FACS, IF - ABIN655408 : Touré, Mzali, Liot, Seguin, Morin, Crouin, Chen-Yang, Tsay, Dorseuil, Gacon, Bertoglio: Phosphoregulation of MgcRacGAP in mitosis involves Aurora B and Cdk1 protein kinases and the PP2A phosphatase. in FEBS letters 2008 (PubMed)


Human Rac GTPase Activating Protein 1 (RACGAP1) interaction partners

  1. High RACGAP1 expression is associated with Basal-like Breast Cancers.

  2. Data suggest that MGCRABGAP (显示 TBC1D21 抗体) is involved in mammalian spermiogenesis by modulating RAB10 (显示 RAB10 抗体).

  3. This study showed that the overexpressions of Ki67 (显示 MKI67 抗体), RacGAP1, and TOP2a (显示 TOP2A 抗体) affect the prognosis of female breast cancer patients adversely

  4. Data confirmed a strong correlation of AURKA (显示 AURKA 抗体) and Wnt (显示 WNT2 抗体)-modulator RACGAP1 gene expression both in the gastric tumor, the tumor-adjacent and the tumor-distant mucosa.

  5. RacGAP1 Is a Novel Downstream Effector of E2F7 (显示 E2F7 抗体)-Dependent Resistance to Doxorubicin and Is Prognostic for Overall Survival in Squamous Cell Carcinoma

  6. RACGAP1 expression levels in the nucleus and cytoplasm, determined by immunohistochemical staining, predict opposite clinical outcomes and that both could be independent prognostic markers for colorectal cancer.

  7. central spindle assembly and 2 Plk1 (显示 PLK1 抗体)-dependent phosphorylations are required to establish efficient binding of the Ect2 (显示 ECT2 抗体) BRCT in early cytokinesis.

  8. RacGAP1 expression at the invasive front in gastric cancer was significantly correlated with factors reflecting tumor progression and poor prognosis.RACGAP1 gene expression in diffuse type gastric cancer was elevated.

  9. RacGAP1 mediated endothelial barrier function loss and melanoma transmigration in a focal adhesion-dependent manner.RacGAP1 activation mediates focal adhesion assembly and actin stress fiber formation.

  10. High RacGAP1 expression was an independent predictive marker for lymph node metastasis, recurrence and poor prognosis in colorectal cancer patients.

Mouse (Murine) Rac GTPase Activating Protein 1 (RACGAP1) interaction partners

  1. Deletion of MgcRacGAP in the male germ cells impairs spermatogenesis and causes male sterility in the mouse.

  2. APC (显示 APC 抗体)(CDH1 (显示 CDH1 抗体)) targets MgcRacGAP for destruction in the late M phase.

  3. TLR4 (显示 TLR4 抗体) signaling shapes B cell dynamics via MyD88 (显示 MYD88 抗体)-dependent pathways and Rac (显示 AKT1 抗体) GTPases.

  4. several Rho family small GTPases activate PI3K by an indirect cooperative positive feedback that required a combination of Rac (显示 AKT1 抗体), CDC42 (显示 CDC42 抗体), and RhoG small GTPase activities

  5. Rac regulates vascular endothelial growth factor stimulated motility

  6. These results indicate that MgcRacGAP regulates cytokinesis and cellular differentiation as a regulator of Rho family of GTPase and suggest that this process is controlled by some serine/threonine kinases.

  7. alpha5 is required for proliferation and polarity of basal epithelial cells; the interaction between laminin-10/11-integrin alpha6beta4 and the PI3-kinase (显示 PIK3CA 抗体)-Cdc42 (显示 CDC42 抗体)/Rac (显示 AKT1 抗体) pathways may play a role in determining the size and shape of tooth germ

  8. Gab2 (显示 GAB2 抗体) via Shp-2 (显示 PTPN11 抗体) is critical for transmitting signals from Kit Tyr (显示 TYR 抗体)(567) to activate the Rac (显示 AKT1 抗体)/JNK (显示 MAPK8 抗体) pathway controlling mast cell proliferation

  9. Data demonstrate that normal cytokinesis in B lymphocytes requires the GAP and NH2 terminal domains but not GAP activity of mgcRacGAP.

  10. Rac (显示 AKT1 抗体) became activated within 2 min after peripheral membrane extensions adhered to new ECM (显示 MMRN1 抗体) islands, and this activation wave propagated outward in an oriented manner as the cells spread from island to island

Zebrafish Rac GTPase Activating Protein 1 (RACGAP1) interaction partners

  1. In vivo cell recordings reveal that gradual loss of wild-type RacGAP1 leads progressively from a failure of abscission, then to cleavage furrow ingression, and finally complete absence of furrow formation. Despite the lack of cytokinesis, gross patterning occurs overtly normally in ogre mutants and cells continue to cycle slowly, some even attaining four or eight nuclei.

RACGAP1 抗原简介


The protein encoded by this gene belongs to the GTPase-activating protein (GAP) family. GAPs bind activated forms of Rho GTPases and stimulate GTP hydrolysis. Through this catalytic function, GAPs negatively regulate Rho-mediated signals. This protein plays a regulatory role in initiation of cytokinesis, controlling cell growth and differentiation of hematopoietic cells, regulating spermatogenesis, and in neuronal proliferation. Alternatively spliced transcript variants have been found for this gene.

Gene names and symbols associated with RACGAP1

  • Rac GTPase activating protein 1 (racgap1) 抗体
  • Rac GTPase activating protein 1 (racgap1.2) 抗体
  • Rac GTPase activating protein 1 (RACGAP1) 抗体
  • Rac GTPase activating protein 1 (Racgap1) 抗体
  • Rac GTPase-activating protein 1 (Racgap1) 抗体
  • Rac GTPase-activating protein 1 (racgap1) 抗体
  • AI227039 抗体
  • AI327394 抗体
  • Band25 抗体
  • cyk-4 抗体
  • CYK4 抗体
  • gtl11 抗体
  • GTPase 抗体
  • HsCYK-4 抗体
  • ID-GAP 抗体
  • MGC121578 抗体
  • MgcRacGAP 抗体
  • mKIAA1478 抗体
  • RACGAP1 抗体
  • wu:fb92c08 抗体
  • zgc:77839 抗体

Protein level used designations for RACGAP1

Rac GTPase activating protein 1 , rac GTPase-activating protein 1-like , GTPase activating protein , male germ cell RacGap , protein CYK4 homolg , protein CYK4 homolog , rac GTPase-activating protein 1 , Rac GTPase-activating protein 1

407917 Xenopus (Silurana) tropicalis
445828 Xenopus laevis
451887 Pan troglodytes
733574 Xenopus (Silurana) tropicalis
100059818 Equus caballus
100453002 Pongo abelii
100473385 Ailuropoda melanoleuca
100542045 Meleagris gallopavo
100558921 Anolis carolinensis
100595184 Nomascus leucogenys
29127 Homo sapiens
431862 Xenopus laevis
486549 Canis lupus familiaris
514618 Bos taurus
100517651 Sus scrofa
426884 Gallus gallus
100354099 Oryctolagus cuniculus
100721177 Cavia porcellus
26934 Mus musculus
315298 Rattus norvegicus
323197 Danio rerio
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