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The protein encoded by RAB2A belongs to the Rab family, members of which are small molecular weight guanosine triphosphatases (GTPases) that contain highly conserved domains involved in GTP binding and hydrolysis. 再加上，我们可以发RAB2A, Member RAS Oncogene Family 抗体 (79) 和 RAB2A, Member RAS Oncogene Family 蛋白 (19)和数多这个蛋白质的别的产品。
Identify Rab2 as a key factor for autophagic and endocytic cargo delivery to and degradation in lysosomes.
our data reveal that RAB2A is new critical membrane trafficking players in the regulation of mesenchymal properties of normal and tumorigenic cells and a critical determinant of an invasive, proteolytic mode of BC progression.
RAB2A variance has effect on the structure and function of the PFC (显示 CFP ELISA试剂盒) and related cognitive functions.
This study demonstrated that RAB2A mutation showing the highest statistical significance in Autism and Schizophrenia.
The immunohistochemistry-based validation using tissue microarray slides in oral squamous cell carcinoma revealed overexpression of the RAB2A and PRDX1 (显示 PRDX1 ELISA试剂盒) gene in 80 and 68 % of the tested clinical cases, respectively.
Pin1 (显示 PIN1 ELISA试剂盒)/Rab2A/Erk (显示 EPHB2 ELISA试剂盒) drives BCSC expansion and tumorigenicity, suggesting potential drug targets.
As a result of the translocations, RAB2A-PLAG1 (显示 PLAG1 ELISA试剂盒), the constitutively active promoter of the partner gene drives the ectopic expression of PLAG1 (显示 PLAG1 ELISA试剂盒).
first X-ray crystal structure of RicA to 2.7 A resolution and have quantified the affinity of RicA binding to human Rab2 in its GDP-bound and nucleotide-free forms
The authors identified a specific interaction between the human small GTPase Rab2 and a Brucella spp. protein named RicA.
The results of this study provided that RAB2A and SLC38A1 (显示 SLC38A1 ELISA试剂盒), were associated with the density of calbindin (显示 CALB1 ELISA试剂盒)-positive neurons and the number of perineuronal oligodendrocytes in psychiatric disorders.
An unprecedented direction of RAB2A-mediated vesicular transport in spermatids during acrosomal biogenesis, from the trans-side of the Golgi apparatus to the nuclear envelope.
These results suggest that the dual effector, Noc2 (显示 RPH3AL ELISA试剂盒), regulates the transition from Rab2a-mediated granule biogenesis to Rab27a (显示 RAB27A ELISA试剂盒)-mediated granule exocytosis.
Symbiotic bacteria directed selective cargo sorting in Paneth cells to promote symbiosis through Nod2 (显示 NOD2 ELISA试剂盒) and LRRK2 (显示 LRRK2 ELISA试剂盒). Deficiency of Nod2 (显示 NOD2 ELISA试剂盒), LRRK2 (显示 LRRK2 ELISA试剂盒) or Rab2a or depletion of commensals resulted in lysosomal degradation of lysozyme (显示 LYZ ELISA试剂盒).
Rab2A is a pivotal switch protein that promotes either secretion or endoplasmic reticulum-associated degradation of (pro)insulin (显示 INS ELISA试剂盒) in insulin (显示 INS ELISA试剂盒)-secreting cells.
CSFV proliferation was promoted by GBF1 (显示 GBF1 ELISA试剂盒) and Rab2 overexpression using a lentiviral system. Hence, Golgi function is important for CSFV multiplication, and GBF1 (显示 GBF1 ELISA试剂盒) and Rab2 participate in CSFV proliferation.
The protein encoded by this gene belongs to the Rab family, members of which are small molecular weight guanosine triphosphatases (GTPases) that contain highly conserved domains involved in GTP binding and hydrolysis. The Rabs are membrane-bound proteins, involved in vesicular fusion and trafficking. This protein is a resident of pre-Golgi intermediates, and is required for protein transport from the endoplasmic reticulum (ER) to the Golgi complex. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
RAB2, member RAS oncogene family
, ras-related protein Rab-2A
, RAB2A, member RAS oncogene family
, GTP-binding protein
, small GTP binding protein RAB2A
, GTP-binding protein (rab2)
, tubulovesicle-membrane-associated GTP-binding protein