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The protein encoded by PPP1R14A belongs to the protein phosphatase 1 (PP1) inhibitor family. 再加上，我们可以发Protein Phosphatase 1, Regulatory (Inhibitor) Subunit 14A 蛋白 (15) 和 Protein Phosphatase 1, Regulatory (Inhibitor) Subunit 14A 试剂盒 (1)和数多这个蛋白质的别的产品。
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Cow (Bovine) Polyclonal PPP1R14A Primary Antibody for WB - ABIN2789677
Xiong, Xia, Tang, Pan, Mei, Xiong: Retromer in Osteoblasts Interacts With Protein Phosphatase 1 Regulator Subunit 14C, Terminates Parathyroid Hormone's Signaling, and Promotes Its Catabolic Response. in EBioMedicine 2016
Hoxb1b is likely to directly regulate ppp1r14al expression in rhombomere 4. Furthermore, ppp1r14al is essential for establishment of the earliest hindbrain signaling-center in rhombomere 4 by regulating expression of fgf3 (显示 FGF3 抗体).
CPI-17 has a role in restoring skin homoeostasis in cutaneous field of cancerization lesions
analysis of the interaction between plakoglobin (显示 JUP 抗体) and CPI-17, which is affected by the phosphorylation status of CPI-17 in human lung microvascular endothelial cells
The N-terminal 21-residue tail domain of CPI-17 is necessary for nuclear localization. Phospho-mimetic Asp (显示 ASIP 抗体)-substitution of CPI-17 at Ser12 attenuates the nuclear import.
The study characterized the CPI-17 promoter and identified binding sites for GATA-6 (显示 GATA6 抗体) and nuclear factor kappa B (NF-kappaB (显示 NFKB1 抗体)).
a novel signaling cascade that links RhoA (显示 RHOA 抗体)-mediated calcium sensitivity to MEF2 (显示 MEF2A 抗体)-dependent myocardin (显示 MYOCD 抗体) expression in VSMCs through a mechanism involving p38 MAPK (显示 MAPK14 抗体), PP1alpha (显示 PPP1CA 抗体), and CPI-17.
RACK1 (显示 GNB2L1 抗体) may play a role in PKC (显示 PRRT2 抗体)/CPI-17 signaling pathway.
cAMP/PKA regulates the endothelial barrier via inhibition of the contractile machinery, mainly by the activation of MLCP via inhibition of CPI-17 and RhoA (显示 RHOA 抗体)/Rock.
mapped to chromosome 19q13.13-q13.2
CPI-17 binds directly to protein kinase C (显示 PKC 抗体) and casein kinase I (显示 CSNK1D 抗体).
importance of PKC (显示 PRRT2 抗体)/CPI-17-mediated pathway in histamine-triggered cytoskeletal rearrangements leading to lung microvascular barrier compromise.
Enhanced vasorelaxation in early endotoxemia is mediated by redox signaling through PKG-1alpha but in later endotoxemia by myosin phosphatase isoform shifts enhancing sensitivity to NO/cGMP as well as smooth muscle atrophy.
a novel signaling cascade that links RhoA (显示 RHOA 抗体)-mediated calcium sensitivity to MEF2 (显示 MEF2C 抗体)-dependent myocardin (显示 MYOCD 抗体) expression in VSMCs through a mechanism involving p38 MAPK (显示 MAPK14 抗体), PP1alpha (显示 PPP1CA 抗体), and CPI-17.
Data suggest that CPI-17 and both conventional and novel PKC isozymes contribute to the phasic and tonic contractile components of BALB/c colonic circular smooth muscle.
Organ-specific mechanisms involving MYPT1 (显示 PPP1R12A 抗体), M-RIP (显示 MPRIP 抗体), and CPI-17 are critical to regulating basal LC20 (显示 MYL9 抗体) phosphorylation in gastrointestinal smooth muscles.
calcium-independent phospholipase A2beta has a role in high glucose-induced activation of RhoA (显示 RHOA 抗体), Rho kinase (显示 ROCK2 抗体), and CPI-17 in cultured vascular smooth muscle cells and vascular smooth muscle hypercontractility in diabetic animals
distribution of mouse and rat PPP1R14A was more specific and different from that of humans
concluded that actions downstream of cGMP/PKG (显示 PRKG1 抗体) can reverse PKC (显示 PKC 抗体)-mediated phosphorylation of CPI-17 and Ca(2 (显示 CA2 抗体)+) sensitization in smooth muscle
findings suggest that CPI-17 was downregulated during intestinal inflammation and that TNF-alpha (显示 TNF 抗体) plays a central role in this process. Downregulation of CPI-17 may play a role in motility impairments in inflammation.
CPI-17 expression is reversibly controlled in response to the phenotype transition of smooth muscle cells that restricts the signal to differentiated smooth muscle cells and particular cell types.
This study examined the protein expression and spatial-temporal distribution of PKCalpha (显示 PKCa 抗体) and CPI-17 in intact smooth muscle tissues.
The protein encoded by this gene belongs to the protein phosphatase 1 (PP1) inhibitor family. This protein is an inhibitor of smooth muscle myosin phosphatase, and has higher inhibitory activity when phosphorylated. Inhibition of myosin phosphatase leads to increased myosin phosphorylation and enhanced smooth muscle contraction. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.
protein phosphatase 1, regulatory (inhibitor) subunit 14A
, protein phosphatase 1 regulatory subunit 14A
, 17 kDa PKC-potentiated inhibitory protein of PP1
, 17-KDa protein
, 17-kDa PKC-potentiated inhibitory protein of PP1
, PKC-potentiated inhibitory protein of PP1
, protein kinase C-potentiated inhibitor protein of 17 kDa