PSME1 抗体
(Proteasome (Prosome, Macropain) Activator Subunit 1 (PA28 Alpha) (PSME1))
The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits\; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. The immunoproteasome contains an alternate regulator, referred to as the 11S regulator or PA28, that replaces the 19S regulator. Three subunits (alpha, beta and gamma) of the 11S regulator have been identified. This gene encodes the alpha subunit of the 11S regulator, one of the two 11S subunits that is induced by gamma-interferon. Three alpha and three beta subunits combine to form a heterohexameric ring. Two transcripts encoding different isoforms have been identified. [provided by RefSeq, Jul 2008].
recommended
recommended
PSME1 适用: 人, 小鼠, Pig, 猴, Bat WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
recommended
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Reactivity
Application
Validations
Cat. No.
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Datasheet
Reactivity
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Application
WB, IHC, ELISA, IP
Validations
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Cat. No.
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Quantity
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Datasheet
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Reactivity
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Application
WB, IHC, IHC (p)
Validations
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Cat. No.
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Quantity
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Datasheet
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Cat. No.
ABIN519415
Quantity
50 μg
Datasheet
Datasheet
Reactivity
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Application
WB, IHC, ELISA, IF, ICC
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Cat. No.
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Quantity
100 μL
Datasheet
Datasheet
Reactivity
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Application
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Cat. No.
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Quantity
200 μL
Datasheet
Datasheet
Reactivity
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Application
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Validations
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Cat. No.
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Quantity
50 μg
Datasheet
Datasheet
Reactivity
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Application
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Validations
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Cat. No.
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Quantity
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Datasheet
Datasheet
Reactivity
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Application
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Validations
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Cat. No.
ABIN651448
Quantity
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Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, IHC, IF, IC
Validations
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Cat. No.
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Quantity
100 μL
Datasheet
Datasheet
Reactivity
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Application
WB, ELISA, IF (cc), IF (p), IHC (p), ICC, IHC (fro)
Validations
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Cat. No.
ABIN5675558
Quantity
100 μL
Datasheet
Datasheet
Reactivity
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Application
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Validations
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Cat. No.
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Quantity
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Datasheet
Datasheet
Reactivity
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Application
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Validations
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Cat. No.
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Quantity
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Datasheet
Datasheet
Reactivity
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Application
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Validations
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Cat. No.
ABIN2855823
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Cynomolgus, Mouse, Rat
Application
WB, ELISA, IHC (p), IHC (fro)
Validations
Cat. No.
ABIN5675559
Quantity
100 μL
Datasheet
Datasheet
Reactivity
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Application
WB, IF (cc), IF (p)
Validations
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Quantity
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Datasheet
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Latest Publications for our PSME1 抗体
: "Modular expression analysis reveals functional conservation between human Langerhans cells and mouse cross-priming dendritic cells." in: The Journal of experimental medicine, Vol. 212, Issue 5, pp. 743-57, (2015) (PubMed).: "Proteomic analysis identifies galectin-1 as a predictive biomarker for relapsed/refractory disease in classical Hodgkin lymphoma." in: Blood, Vol. 117, Issue 24, pp. 6638-49, (2011) (PubMed).
: "Anti-20S proteasome autoantibodies inhibit proteasome stimulation by proteasome activator PA28." in: Arthritis and rheumatism, Vol. 54, Issue 7, pp. 2175-83, (2006) (PubMed).
Aliases for PSME1 抗体
proteasome activator subunit 1 (psme1) 抗体proteasome activator subunit 1 (PSME1) 抗体
proteasome activator subunit 1 (Psme1) 抗体
proteasome (prosome, macropain) activator subunit 1 (PA28 alpha) (Psme1) 抗体
AW413925 抗体
fk89d05 抗体
IFI5111 抗体
PA28A 抗体
PA28a 抗体
PA28alpha 抗体
REGalpha 抗体
wu:fk89d05 抗体
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