anti-Prolylcarboxypeptidase (PRCP) 抗体

The protein encoded by PRCP is a lysosomal prolylcarboxypeptidase, which cleaves C-terminal amino acids linked to proline in peptides such as angiotension II, III and des-Arg9-bradykinin. 再加上,我们可以发Prolylcarboxypeptidase 试剂盒 (41)Prolylcarboxypeptidase 蛋白 (12)和数多这个蛋白质的别的产品。

列出全部抗体 基因 基因ID UniProt
PRCP 649 P13497
PRCP 72461 Q7TMR0
PRCP 293118  

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Showing 10 out of 67 products:

产品编号 适用 宿主 标记 应用范围 图像 规格 供应商 交付 价格 详细
非结合性 IF (p), IHC (p), WB Antigen: 0.2 µg/100 µL  Primary: Antiserum, 1:500, 1:1000, 1:2000, 1:4000, 1:8000, 1:16000, 1:32000;  Secondary: HRP conjugated Goat Anti-Rabbit IgG at 1: 5000;  TMB staining; Read the data in MicroplateReader by 450nm. Antigen: 0.2 µg/100 µL Primary: Antiserum, 1:500, 1:1000, 1:2000, 1:4000, 1:8000, 1:16000, 1:32000; Secondary: HRP conjugated Goat Anti-Rabbit IgG at 1: 5000; TMB staining; Read the data in Microplate Reader by 450nm 100 μL Log in to see 5至7个工作日
¥2,610.23
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非结合性 IHC, WB Western blot analysis of extract of rat kidney cells, using PRCP antibody. 100 μL Log in to see 34至38个工作日
¥4,083.86
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大鼠 非结合性 ICC, IHC, IP, WB 100 μg Log in to see 7至10个工作日
¥1,839.59
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Cy3 IF (p)   100 μL Log in to see 14至17个工作日
¥3,555.98
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Cy5 IF (p)   100 μL Log in to see 14至17个工作日
¥3,555.98
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Cy5.5 IF (p)   100 μL Log in to see 14至17个工作日
¥3,555.98
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Cy7 IF (p)   100 μL Log in to see 14至17个工作日
¥3,555.98
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FITC IF (p)   100 μL Log in to see 14至17个工作日
¥3,555.98
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HRP IHC (p), WB   100 μL Log in to see 14至17个工作日
¥3,555.98
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Alexa Fluor 350 IF (p)   100 μL Log in to see 14至17个工作日
¥3,555.98
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通过反应活性、应用领域、克隆类型和共轭标记 PRCP 抗体

特性 应用范围 宿主 克隆类型 标记
Human ,
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Mouse (Murine) ,


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Rat (Rattus) ,


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更多抗Prolylcarboxypeptidase的相互作用对抗体

Human Prolylcarboxypeptidase (PRCP) interaction partners

  1. Given the association of BMP1 (显示 BMP1 抗体)-related Osteogenesis Imperfecta (显示 COL1A2 抗体) (OI) with very high bone material density, concerns remain whether anti-resorptive therapy is indicated in this ultra-rare form of OI

  2. Data show that the KKN1 fragment generated by BMP1 (显示 BMP1 抗体)-cleavage of WFIKKN1 (显示 WFIKKN1 抗体) protein contributes most significantly to the observed enhancer activity.

  3. For the first time, PRCP is identified as an apelin (显示 APLN 抗体)-cleaving enzyme.

  4. a previously unknown O-glycosylation site and Asn-hydroxylation site, indicating a novel feature of BMP-1 (显示 BMP1 抗体) in the EGF (显示 EGF 抗体) domain. The study clearly outlines the benefit of in-depth characterization of overexpressed proteins to deduce important protein modifications.

  5. BMP-1 (显示 BMP1 抗体) accelerates the connective tissue growth factor (显示 CTGF 抗体) production dependently on cellular internalization in human dental pulp cells, indicating a novel property of BMP-1 (显示 BMP1 抗体) which potentially enhances bone-like reparative dentin formation.

  6. Studies indicate crosstalk between Notch receptor and Wnt protein, Hedgehog protein, hypoxia and transforming growth factor beta (TGFbeta)/bone morphogenetic protein (BMP) pathways.

  7. study thus highlights the severe and progressive nature of BMP1 (显示 BMP1 抗体)-associated OI in adults and broadens insights into the functional consequences of BMP1/mTLD-deficiency on ECM (显示 MMRN1 抗体) organization.

  8. Data indicate that BMP-1 (显示 BMP1 抗体) can simultaneously trigger matrix assembly and boost the synthesis of matrix proteins via a direct effect on growth factors in the contexts of development, growth and tissue repair. [review]

  9. The decrease in PRCP levels in the first 24 h after stroke onset is associated with stroke severity and an unfavourable short-term stroke outcome

  10. Two novel variants in the BMP1 (显示 BMP1 抗体) gene: c.808A>G and c.1297G>T care associated with osteogenesis imperfecta (显示 COL1A2 抗体).

Mouse (Murine) Prolylcarboxypeptidase (PRCP) interaction partners

  1. This study demonistrated that PRCP gene is broadly expressed in the brain.

  2. PRCP regulates cell growth, angiogenesis, and the response to vascular injury

  3. ACE2 (显示 ACE2 抗体) metabolizes ANG II (显示 AGT 抗体) in the kidney at neutral and basic pH, while prolylcarboxypeptidase catalyzes the same reaction at acidic pH.

  4. PRCP is an important regulator of energy and glucose homeostasis since its deletion significantly improves metabolic parameters in mice exposed to both standard chow diet and high-fat diet

  5. analysis of non-benzimidazole and brain-penetrant prolylcarboxypeptidase inhibitors

  6. This study showed that PRCP mutant mice have a significant decrease in fat mass, although an increase in lean mass was also observed; reduced leptin (显示 LEP 抗体) levels and increased energy expenditure were also found.

  7. Murine prolylcarboxypeptidase depletion induces vascular dysfunction with hypertension and faster arterial thrombosis.

  8. PRCP is an important component of melanocortin signaling and weight maintenance via control of active alpha-MSH1-13 levels.

Prolylcarboxypeptidase (PRCP) 抗原简介

蛋白简介

The protein encoded by this gene is a lysosomal prolylcarboxypeptidase, which cleaves C-terminal amino acids linked to proline in peptides such as angiotension II, III and des-Arg9-bradykinin. The cleavage occurs at acidic pH, but the enzyme activity is retained with some substrates at neutral pH. This enzyme has been shown to be an activator of the cell matrix-associated prekallikrein. The importance of angiotension II, one of the substrates of this enzyme, in regulating blood pressure and electrolyte balance suggests that this gene may be related to essential hypertension. Alternatively spliced transcript variants encoding distinct isoforms have been observed.

Gene names and symbols associated with PRCP

  • prolylcarboxypeptidase (angiotensinase C) (PRCP) 抗体
  • prolylcarboxypeptidase (angiotensinase C) (prcp) 抗体
  • prolylcarboxypeptidase (AaeL_AAEL005521) 抗体
  • prolylcarboxypeptidase (CpipJ_CPIJ006123) 抗体
  • prolylcarboxypeptidase (CpipJ_CPIJ006124) 抗体
  • bone morphogenetic protein 1 (BMP1) 抗体
  • prolylcarboxypeptidase (angiotensinase C) (Prcp) 抗体
  • 2510048K03Rik 抗体
  • 2610104A14Rik 抗体
  • AI451719 抗体
  • HUMPCP 抗体
  • MGC145178 抗体
  • OI13 抗体
  • PCOLC 抗体
  • PCP 抗体
  • PCP2 抗体
  • TLD 抗体

Protein level used designations for PRCP

prolylcarboxypeptidase , mammalian tolloid protein , procollagen C-endopeptidase , procollagen C-proteinase , lysosomal Pro-X carboxypeptidase , proline carboxypeptidase , angiotensinase C , lysosomal carboxypeptidase C , prolylcarboxypeptidase isoform 1 preproprotein

GENE ID SPECIES
100061830 Equus caballus
780095 Xenopus (Silurana) tropicalis
5579822 Aedes aegypti
6038068 Culex quinquefasciatus
6038069 Culex quinquefasciatus
649 Homo sapiens
72461 Mus musculus
5547 Homo sapiens
476788 Canis lupus familiaris
534927 Bos taurus
293118 Rattus norvegicus
100734342 Cavia porcellus
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