anti-Potassium Voltage-Gated Channel, Subfamily H (Eag-Related), Member 2 (KCNH2) 抗体

KCNH2 encodes a voltage-activated potassium channel belonging to the eag family. 再加上,我们可以发Potassium Voltage-Gated Channel, Subfamily H (Eag-Related), Member 2 蛋白 (8)和数多这个蛋白质的别的产品。

列出全部抗体 基因 基因ID UniProt
KCNH2 3757 Q12809
KCNH2 16511  
KCNH2 117018 O08962

antibodies-online.cn销售最多的anti-Potassium Voltage-Gated Channel, Subfamily H (Eag-Related), Member 2 抗体

Showing 10 out of 94 products:

产品编号 适用 宿主 标记 应用范围 图像 规格 供应商 交付 价格 详细
Cow 非结合性 WB <b>WB Suggested Anti-KCNH2 Antibody Titration: </b>0.2-1 ug/ml<br><b>ELISA Titer: </b>1:62500<br><b>Positive Control: </b>OVCAR-3 cell lysate 100 μL Log in to see 5至7个工作日
¥20,898.73
详细
Cow 非结合性 WB WB Suggested Anti-Kcnh2 Antibody Titration: 1.0 ug/ml Positive Control: Mouse Kidney 100 μL Log in to see 5至7个工作日
¥20,898.73
详细
非结合性 WB Anti- KCNH2 Picoband antibody, Western blotting All lanes: Anti KCNH2  at 0.5ug/ml Lane 1: Rat Brain Tissue Lysate at 50ug Lane 2: HELA Whole Cell Lysate at 40ug Lane 3: COLO320 Whole Cell Lysate at 40ug Lane 4: MM231 Whole Cell Lysate at 40ug Predicted bind size: 127KD Observed bind size: 127KD Anti- KCNH2 Picoband antibody, Western blotting All lanes: Anti KCNH2  at 0.5ug/ml WB: Recombinant Human KCNH2 Protein 0.5ng Predicted bind size: 42KD Observed bind size: 42KD 100 μg Log in to see 26至32个工作日
¥2,919.96
详细
非结合性 EIA, WB Western blot analysis of KCNH2 Antibody (Center) in CEM cell line lysates (35ug/lane).KCNH2 (arrow) was detected using the purified Pab. 0.4 mL Log in to see 29至35个工作日
¥4,086.26
详细
非结合性 FACS, WB Western blot analysis of KCNH2 Antibody (Center) (ABIN652759) in CEM cell line lysates (35 µg/lane).KCNH2 (arrow) was detected using the purified polyclonal antibody. 400 μL Log in to see 5至8个工作日
¥2,325.14
详细
Bat 非结合性 IHC (p) Anti-KCNH2 / Kv11.1 antibody  ABIN1048984 IHC staining of human brain, cerebellum. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. 50 μg Log in to see 29至35个工作日
¥4,324.07
详细
Cow 非结合性 IHC (p) Anti-KCNH2 / Kv11.1 antibody  ABIN1048985 IHC staining of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. 50 μg Log in to see 29至35个工作日
¥4,324.07
详细
非结合性 IF (p), IHC (p), WB   100 μL Log in to see 5至7个工作日
¥2,610.23
详细
非结合性 WB Western blot analysis of extracts of various cell lines, using KCNH2 antibody. 100 μL Log in to see 34至38个工作日
¥2,882.69
详细
Cow 非结合性 IHC (p), WB 50 μg Log in to see 29至35个工作日
¥5,538.93
详细

通过反应活性、应用领域、克隆类型和共轭标记 KCNH2 抗体

特性 应用范围 宿主 克隆类型 标记
Human , , ,


, , , , , , , , , , , , , , , , , , ,
Mouse (Murine) , ,


, , , , , , , , , , , , , , , ,
Rat (Rattus) , ,


, , , , , , , , , , , , , , , ,

引用最多的anti-Potassium Voltage-Gated Channel, Subfamily H (Eag-Related), Member 2 抗体

  1. Dog (Canine) Polyclonal KCNH2 Primary Antibody for IF (p), IHC (p) - ABIN734843 : Zhao, Xu, Yun, Zhao, Li, Gong, Yuan, Yan, Zhang, Ding, Wang, Zhang, Dong, Xiu, Yang, Liu, Xue, Li: Chronic obstructive sleep apnea causes atrial remodeling in canines: mechanisms and implications. in Basic research in cardiology 2014 (PubMed)

更多抗Potassium Voltage-Gated Channel, Subfamily H (Eag-Related), Member 2的相互作用对抗体

Zebrafish Potassium Voltage-Gated Channel, Subfamily H (Eag-Related), Member 2 (KCNH2) interaction partners

  1. RNF207 is an important regulator of action potential duration, likely via effects on HERG trafficking and localization in a heat shock protein-dependent manner.

  2. The data support the conclusion that zerg-2 and zerg-3 are apparent orthologues of different human genes encoding potassium ion channels, but that their functions have switched compared to the respective human proteins.

  3. role for ERG in leukocytes, where inhibition or translational knockdown of ERG resulted in significant attenuation of the inflammatory response to an infectious stimulus

  4. Mutations in kcnh2 recapitulate the human long QT syndrome (LQTS) phenotype as manifested by prolongation of action potentials and prolonged QT interval in the first animal genetic model of human LQTS type 2.

  5. The reg mutation in the voltage sensor of the ether-a-go-go-related gene gene K+ channel (显示 KCNC4 抗体) causes premature zERG channel activation & defective inactivation, resulting in shortened action-potential duration & accelerated cardiac repolarization

Human Potassium Voltage-Gated Channel, Subfamily H (Eag-Related), Member 2 (KCNH2) interaction partners

  1. Expression and functions of hERG are regulated by specific miRNAs.

  2. The present study shows clinical and genetic aspects of p.His492Tyr carriers and demonstrated two major findings; (1) KCNH2 p.His492Tyr variant presented symptomatic Romano-Ward syndrome in the presence of another LQTS-related gene mutation, in contrast, (2) heterozygous carriers had mild QT prolongation while additional triggers can be "latent" form of p.His492Tyr

  3. Homozygous carriers of CYP2B6 (显示 CYP2B6 抗体)*6 allele may be at increased risk for EFV-induced QT interval prolongation via inhibition of hERG.

  4. ER-located J-protein chaperones were identified as key regulators for the iogenesis and physiological function of ERG (显示 ERG 抗体) K+ channels. They regulate two distinct aspects of K+ channel (显示 KCNC4 抗体) biogenesis, the stabilization and assembly of channel subunits.

  5. atypical sequence of the pore helix of hERG may play a key role in determining how anionic lipids influence its gating

  6. Besides a prolonged cardiac repolarization phase, LQT2 patients display increased GLP-1 (显示 GCG 抗体), GIP (显示 GIP 抗体), and insulin (显示 INS 抗体) secretion and defective glucagon (显示 GCG 抗体) secretion, causing decreased plasma glucose and thus increased risk of hypoglycemia.

  7. BIMU8 is a potent blocker of hERG, NaV1.5 (显示 SCN5A 抗体) and CaV1.2 (显示 CACNA1C 抗体) cardiac ion channels, inducing cardiac arrhythmias.

  8. The K897T polymorphism in the hERG1 gene has been reported as an important modifier of the IKr current, probably leading to QT interval prolongation-as it is observed in the LQT2 syndrome.

  9. Stabilization of the Activated hERG Channel Voltage Sensor by Depolarization Involves the S4-S5 Linker

  10. Study determined the structure of hERG using cryo-electron microscopy; the voltage sensors are depolarized, and the inner helical gate is open; an unusual geometry of the "central cavity" within hERG's ion conduction pathway; hERG contains a subtle difference in the structure of its selectivity filter compared to all other K+ channels so far analyzed.

Rabbit Potassium Voltage-Gated Channel, Subfamily H (Eag-Related), Member 2 (KCNH2) interaction partners

  1. RNF207 is an important regulator of action potential duration, likely via effects on HERG trafficking and localization in a heat shock protein-dependent manner.

  2. In transgenic long QT syndrome rabbits, Kv11.1 channel activation shortens the cardiac activation potential duration.

Mouse (Murine) Potassium Voltage-Gated Channel, Subfamily H (Eag-Related), Member 2 (KCNH2) interaction partners

  1. Using a combination of mouse genetics, biochemistry, molecular and cell biology, we demonstrate that Nkx2-5 (显示 NKX2-5 抗体) regulates the gene encoding Kcnh2 channel and others, shedding light on potential mechanisms generating electrical abnormalities observed in patients bearing NKX2-5 (显示 NKX2-5 抗体) dysfunction and opening opportunities to the study of novel therapeutic targets for anti-arrhythmogenic therapies

  2. Report altered protein trafficking/function of mouse ERG K(+) channel clones.

  3. Enhancement of HERG protein expression through Hsp90 (显示 HSP90 抗体) inhibition of CHIP binding might be a novel therapeutic strategy for long QT syndrome 2 caused by trafficking abnormalities of HERG proteins.

  4. The findings of this study suggested that MERG1a may not modulate Murf1 (显示 TRIM63 抗体) expression through the AKT (显示 AKT1 抗体)/FOXO (显示 FOXO3 抗体) pathway.

  5. Data indicate presence of KCNH2 in left/right atria & indicate functional interaction between KCNH2 & KCNA5 (显示 KCNA5 抗体). Kinetic analyses confirm KCNH2 as "rapid" and KCNA5 (显示 KCNA5 抗体) as "ultra rapid" potassium channels.

  6. Knockdown of mERG1 transcripts with small interfering RNA (siRNA) dramatically reduced I (Kr) amplitude, confirming the molecular link of mERG1 and I (Kr) in HL-1 (显示 ASGR1 抗体) cells.

  7. The LQT2 missense mutations G601S and N470D hERG exhibited altered protein trafficking in mouse cardiomyocytes.

  8. ERG1 B is necessary for I(Kr) expression in the surface membrane of adult myocytes. Knockout of ERG1 B predisposes mice to episodic sinus bradycardia.

  9. erg1 gene expression pattern in the developing embryo.

  10. MERG1A is developmentally regulated, and it might play a role in early mouse embryogenic development.

Potassium Voltage-Gated Channel, Subfamily H (Eag-Related), Member 2 (KCNH2) 抗原简介

蛋白简介

This gene encodes a voltage-activated potassium channel belonging to the eag family. It shares sequence similarity with the Drosophila ether-a-go-go (eag) gene. Mutations in this gene can cause long QT syndrome type 2 (LQT2). Transcript variants encoding distinct isoforms have been identified.

Gene names and symbols associated with KCNH2

  • potassium voltage-gated channel, subfamily H (eag-related), member 2 (kcnh2) 抗体
  • potassium voltage-gated channel, subfamily H (eag-related), member 2 (KCNH2) 抗体
  • potassium voltage-gated channel subfamily H member 2-like (LOC100858122) 抗体
  • potassium voltage-gated channel subfamily H member 2-like (LOC100523293) 抗体
  • potassium voltage-gated channel, subfamily H (eag-related), member 2 (Kcnh2) 抗体
  • potassium voltage-gated channel, subfamily H (eag-related), member 6 (KCNH6) 抗体
  • AI326795 抗体
  • cerg 抗体
  • derg 抗体
  • ERG 抗体
  • erg1 抗体
  • gp-erg 抗体
  • HERG 抗体
  • HERG1 抗体
  • KCNH2 抗体
  • Kv11.1 抗体
  • LQT 抗体
  • Lqt2 抗体
  • M-erg 抗体
  • Merg1 抗体
  • merg1a 抗体
  • merg1b 抗体
  • SQT1 抗体

Protein level used designations for KCNH2

bre , breakdance , erg K+ channel , reg , reggae , silent ventricle , unm s213 , zerg , potassium voltage-gated channel, subfamily H (eag-related), member 2 , potassium voltage-gated channel subfamily H member 2-like , ERG-1 , H-ERG , eag homolog , eag-related protein 1 , ether-a-go-go-related gene potassium channel 1 , ether-a-go-go-related potassium channel protein , ether-a-go-go-related protein 1 , hERG-1 , potassium voltage-gated channel subfamily H member 2 , voltage-gated potassium channel subunit Kv11.1 , c-ERG , eag related protein 1 , ether-a-go-go related gene potassium channel 1 , potassium channel protein ERG , ERG1 , RERG , ra-erg , ventricular ERG K+ channel subunit , voltage-gated potassium channel 11.1 , voltage-gated potassium channel, subfamily H, member 2 , MERG , ether a go-go related , r-ERG , Ether-a-go-go-related gene potassium channel 1 , Potassium voltage-gated channel subfamily H member 2 , HERG protein

GENE ID SPECIES
405763 Danio rerio
463894 Pan troglodytes
100064000 Equus caballus
100413935 Callithrix jacchus
100447585 Pongo abelii
100858122 Gallus gallus
100523293 Sus scrofa
3757 Homo sapiens
403761 Canis lupus familiaris
100009242 Oryctolagus cuniculus
16511 Mus musculus
117018 Rattus norvegicus
397334 Sus scrofa
100135563 Cavia porcellus
414871 Gallus gallus
anti-Potassium Voltage-Gated Channel, Subfamily H (Eag-Related), Member 2 (KCNH2) 抗体 精选生产商
您还需要查找其他产品吗?