Potassium Voltage-Gated Channel, Shaker-Related Subfamily, Member 5 (KCNA5) ELISA试剂盒

Potassium channels represent the most complex class of voltage-gated ino channels from both functional and structural standpoints. 再加上,我们可以发Potassium Voltage-Gated Channel, Shaker-Related Subfamily, Member 5 抗体 (91)Potassium Voltage-Gated Channel, Shaker-Related Subfamily, Member 5 蛋白 (4)和数多这个蛋白质的别的产品。

list all ELISA KIts 基因 基因ID UniProt
KCNA5 3741 P22460
小鼠 KCNA5 KCNA5 16493 Q61762
大鼠 KCNA5 KCNA5 25470 P19024

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0.188 ng/mL 0.313-20 ng/mL   96 Tests Log in to see 7至10个工作日
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Human Potassium Voltage-Gated Channel, Shaker-Related Subfamily, Member 5 (KCNA5) interaction partners

  1. our finding indicated that KCNA5 protein may interact with Cav-1 (显示 CAV1 ELISA试剂盒), thereby contributing to the proliferation and early transformation of mammary cells.

  2. Studies demonstrate that DNA hypermethylation contributes to epigenetic repression of the KCNA5 locus and that the resulting suppression of the Kv1.5 ion channel supports cancer cell proliferation.

  3. Kv1.5 expression is increased in osteosarcoma cells and tissues and shRNA mediated silencing of Kv1.5 results in cell proliferation inhibition, cell cycle arrest, and induces cell apoptosis.

  4. demonstrate that PK treatment cleaved mature membrane-bound (75kDa) Kv1.5 channels at a single locus in the S1-S2 linker, producing 42-kDa N-terminal fragments and 33-kDa C-terminal fragments

  5. These results indicate that CHIP decreases the Kv1.5 protein level and functional channel by facilitating its degradation in concert with chaperone Hsc70 (显示 HSPA8 ELISA试剂盒)

  6. The expression of Kv1.5 channel protein changes with atrial fibrillation but not with age, rheumatic heart diseases, and sex in atrial fibrillation.

  7. One KCNA5 variant, H463R, was a novel mutation; the histidine at codon 463 is located in the S5-pore loop, in the vicinity of the pore of KV1.5 subunit. The other variant, T527M, showed a gain-of-function effect with an enhanced steady-state activation.

  8. The KCNA5 promoter is marked in cancer cells with PcG-dependent chromatin repressive modifications that increase in hypoxia.

  9. Mutations in KCNA5 gene is not associated with pulmonary arterial hypertension.

  10. Protein kinase C (显示 PKC ELISA试剂盒) inhibition results in a Kv 1.5 and Kv beta 1.3 pharmacology closer to Kv 1.5 channels

Mouse (Murine) Potassium Voltage-Gated Channel, Shaker-Related Subfamily, Member 5 (KCNA5) interaction partners

  1. Silencing of Kv1.5 improved endothelium-dependent vasodilatation in thoracic aorta from type 2 diabetes mice.

  2. Intracellular urate taken up by UATs enhanced Kv1.5 protein expression and function in HL-1 (显示 ASGR1 ELISA试剂盒) atrial myocytes.

  3. JAK3 (显示 JAK3 ELISA试剂盒) contributes to the regulation of membrane Kv1.5 protein abundance and activity, an effect sensitive to ouabain and thus possibly involving Na(+)/K(+) ATPase (显示 ATP1A1 ELISA试剂盒) activity.

  4. KV1.5, a DPO-1-sensitive KDR (显示 KDR ELISA试剂盒) channel, plays a major role in determining microvascular tone and the response to vasoconstrictors and vasodilators.

  5. Kv1.5 channels in vascular smooth muscle play a critical role in coupling myocardial blood flow to cardiac metabolism.

  6. the Kv1.5 subunit has a role in electrical remodeling of preoptic GABAergic neurons

  7. MYO5A (显示 MYO5A ELISA试剂盒) and MYO5B control functionally distinct steps in the surface trafficking of Kv1.5.

  8. e-LXA4 promoted a modest upregulation of Kv1.5 mRNA that was suppressed by LPS (显示 TLR4 ELISA试剂盒) or IL-4 (显示 IL4 ELISA试剂盒)/IL-13 (显示 IL13 ELISA试剂盒).

  9. The combined down-regulation of Kv4.2 (显示 KCND2 ELISA试剂盒), Kv1.5 and KChIP2 (显示 KCNIP2 ELISA试剂盒) prior to the onset of HF may play an important role in the premature sudden death in this DCM model.

  10. cortactin (显示 CTTN ELISA试剂盒) was required for N-cadherin (显示 CDH2 ELISA试剂盒)-mediated enhancement of Kv1.5 channel activity

Potassium Voltage-Gated Channel, Shaker-Related Subfamily, Member 5 (KCNA5) 抗原简介

Antigen Summary

Potassium channels represent the most complex class of voltage-gated ino channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. Four sequence-related potassium channel genes - shaker, shaw, shab, and shal - have been identified in Drosophila, and each has been shown to have human homolog(s). This gene encodes a member of the potassium channel, voltage-gated, shaker-related subfamily. This member contains six membrane-spanning domains with a shaker-type repeat in the fourth segment. It belongs to the delayed rectifier class, the function of which could restore the resting membrane potential of beta cells after depolarization and thereby contribute to the regulation of insulin secretion. This gene is intronless, and the gene is clustered with genes KCNA1 and KCNA6 on chromosome 12. Defects in this gene are a cause of familial atrial fibrillation type 7 (ATFB7).

Gene names and symbols associated with KCNA5

  • potassium voltage-gated channel, shaker-related subfamily, member 5 (KCNA5) 抗体
  • potassium voltage-gated channel, shaker-related subfamily, member 5 (kcna5) 抗体
  • potassium voltage-gated channel, shaker-related subfamily, member 5 (Kcna5) 抗体
  • ATFB7 抗体
  • HCK1 抗体
  • HK2 抗体
  • HPCN1 抗体
  • kcna5 抗体
  • Kv1 抗体
  • Kv1.5 抗体
  • PCN1 抗体

Protein level used designations for KCNA5

potassium voltage-gated channel, shaker-related subfamily, member 5 , potassium voltage-gated channel subfamily A member 5-like , cardiac potassium channel , insulinoma and islet potassium channel , potassium channel 1 , potassium voltage-gated channel subfamily A member 5 , voltage-gated potassium channel HK2 , voltage-gated potassium channel protein Kv1.5 , voltage-gated potassium channel subunit Kv1.5 , KV1-5 , Potassium (K+) channel protein alpha 5 , RCK7 , RK4 , potassium voltage gated channel, shaker related subfamily, member 5 , shaker subfamily potassium channel Kv1.5 alpha subunit , delayed rectifier K+ channel , Kv1.5 potassium channel , potassium voltage-gated channel shaker-related subfamily member 5 , potassium voltage-gated channel shaker-related subfamily 5 , potassium channel Kv1.5 , voltage-gated potassium channel Kv1.5

GENE ID SPECIES
466930 Pan troglodytes
496997 Xenopus (Silurana) tropicalis
100431806 Pongo abelii
3741 Homo sapiens
16493 Mus musculus
25470 Rattus norvegicus
395115 Gallus gallus
403995 Canis lupus familiaris
474166 Sus scrofa
508960 Bos taurus
100008684 Oryctolagus cuniculus
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