anti-Potassium Large Conductance Calcium-Activated Channel, Subfamily M, beta Member 4 (KCNMB4) 抗体

MaxiK channels are large conductance, voltage and calcium-sensitive potassium channels which are fundamental to the control of smooth muscle tone and neuronal excitability. 再加上,我们可以发KCNMB4 蛋白 (5)和数多这个蛋白质的别的产品。

列出全部抗体 基因 基因ID UniProt
KCNMB4 435726  
KCNMB4 27345 Q86W47
KCNMB4 66016 Q9ESK8

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Showing 10 out of 46 products:

产品编号 适用 宿主 标记 应用范围 图像 规格 供应商 交付 价格 详细
Cow 非结合性 WB <b>WB Suggested Anti-KCNMB4 Antibody Titration: </b>0.2-1 ug/ml<br><b>ELISA Titer: </b>1:312500<br><b>Positive Control: </b>THP-1 cell lysate 100 μL Log in to see 5至7个工作日
¥20,898.73
详细
小鼠 非结合性 ELISA Detection limit for recombinant GST tagged KCNMB4 is approximately 0.3 ng/mL as a capture antibody. 0.1 mg Log in to see 11至15个工作日
¥3,179.71
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Bat 非结合性 WB 50 μg Log in to see 29至35个工作日
¥5,538.93
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非结合性 WB Western blot analysis of KCNMB4 expression in THP1 (A) whole cell lysates. 200 μL Log in to see 7至8个工作日
¥3,941.44
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非结合性 IHC (p), WB Human Brain, Cortex: Formalin-Fixed, Paraffin-Embedded (FFPE) 50 μL Log in to see 29至35个工作日
¥4,324.07
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非结合性 ICC, IF Immunocytochemistry/Immunofluorescence: KCNMB4 Antibody  - Staining of human cell line RT4 shows localization to cytosol. 100 μL Log in to see 28至35个工作日
¥3,591.24
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大鼠 非结合性 IHC, WB   100 μL Log in to see 28至33个工作日
¥11,426.38
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非结合性 WB KCNMB4 antibody used at 1 ug/ml to detect target protein. 50 μg Log in to see 24至29个工作日
¥11,910.48
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小鼠 非结合性 ELISA Detection limit for recombinant GST tagged KCNMB4 is approximately 0.3ng/ml as a capture antibody. 100 μg Log in to see 29至34个工作日
¥3,169.73
详细
非结合性 WB   100 μL Log in to see 24至29个工作日
¥4,670.89
详细

通过反应活性、应用领域、克隆类型和共轭标记 KCNMB4 抗体

特性 应用范围 宿主 克隆类型 标记
Mouse (Murine) ,
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Rat (Rattus) ,


引用最多的anti-KCNMB4 抗体

  1. Mammalian Monoclonal KCNMB4 Primary Antibody for ISt, IHC - ABIN1304561 : Shruti, Urban-Ciecko, Fitzpatrick, Brenner, Bruchez, Barth: The brain-specific Beta4 subunit downregulates BK channel cell surface expression. in PLoS ONE 2012 (PubMed)
    Show all 3 Pubmed References

更多抗KCNMB4的相互作用对抗体

Mouse (Murine) Potassium Large Conductance Calcium-Activated Channel, Subfamily M, beta Member 4 (KCNMB4) interaction partners

  1. These results indicate that an important role of the beta4-subunit is to reduce ryanodine receptor (显示 RYR3 抗体)-BK channel (显示 KCNMA1 抗体) functional coupling during the afterhyperpolarization component of the action potential, thereby decreasing excitability of dentate gyrus neurons.

  2. the enhanced effect of amiloride on potassium secretion in wild-type compared to knockout mice on the alkaline diet clarify a BK- alpha/beta4-mediated potassium secretory pathway in intercalated cells driven by ENaC (显示 SCNN1A 抗体)-mediated sodium reabsorption

  3. BKbeta4 expression in astrocytes likely participates in regulating astrocytic voltage gradients and maintaining potassium homeostasis, hence enabling astrocytes to fulfill their complex regulatory influence on proper brain function.

  4. E2 at physiological concentrations augments K(Ca) currents through ERbeta (显示 ESR2 抗体) in the GT1 (显示 MYL4 抗体)-7 GnRH (显示 GNRH1 抗体) neuronal cell line and increases the expression of the BK channel (显示 KCNMA1 抗体) subunit mRNAs, alpha and beta4

  5. results argue that, for native mouse Slo3 (显示 KCNU1 抗体) channels, the beta4 subunit must be considered as a potential interaction partner and, furthermore, that KCNMB subunits may have functions unrelated to regulation of the Slo1 (显示 KCNMA1 抗体) alpha subunit (显示 POLG 抗体)

Human Potassium Large Conductance Calcium-Activated Channel, Subfamily M, beta Member 4 (KCNMB4) interaction partners

  1. Two recurrent fusion genes associated with the 12q locus, LRP1 (显示 LRP1 抗体)-SNRNP25 (显示 SNRNP25 抗体) and KCNMB4-CCND3 (显示 CCND3 抗体), were by RT-PCR, Sanger sequencing and FISH, and were found to be osteosarcoma specific in a validation cohort of 240 other sarcomas.

  2. Recombinant martentoxin selectively blocks KCNMA1 (显示 KCNMA1 抗体)/KCNMB4 channels.

  3. BK channel (显示 KCNMA1 抗体) beta4 subunit influences sensitivity and tolerance to alcohol by altering its response to kinases

  4. Study shows that beta4 subunit of the MaxiK (显示 KCNMA1 抗体) channel has no potential endocytic signal and 2 specific amino acids in the functional basic motif retention/retrieval trafficking signal at the C-terminus may play a role in controlling cellular excitability

  5. IFN-gamma (显示 IFNG 抗体) changed mRNA levels of the BK beta-modulatory proteins KCNMB2 (显示 KCNMB2 抗体) (increased) and KCNMB4 (decreased) as well as leucine-rich repeat-containing protein (LRRC)26 (显示 LRRC26 抗体) (decreased).

  6. our data suggest that the rs398702 variant in the KCNMB4 gene is unlikely to influence significantly the risk of developing mesial temporal lobe epilepsy or its severity

  7. Report beta subunit (显示 POLG 抗体) (KNMB1-4)-specific modulations of BK channel (显示 KCNMA1 抗体) function by a Slo1 (显示 KCNMA1 抗体) mutation associated with epilepsy and dyskinesia.

  8. results argue that, for native mouse Slo3 (显示 KCNU1 抗体) channels, the beta4 subunit must be considered as a potential interaction partner and, furthermore, that KCNMB subunits may have functions unrelated to regulation of the Slo1 (显示 KCNMA1 抗体) alpha subunit (显示 POLG 抗体)

Pig (Porcine) Potassium Large Conductance Calcium-Activated Channel, Subfamily M, beta Member 4 (KCNMB4) interaction partners

  1. The study verified that the BK(Ca) channel alpha-subunit (显示 POLG 抗体) is located to smooth muscle cells of porcine basilar and middle cerebral arteries.

KCNMB4 抗原简介

蛋白简介

MaxiK channels are large conductance, voltage and calcium-sensitive potassium channels which are fundamental to the control of smooth muscle tone and neuronal excitability. MaxiK channels can be formed by 2 subunits: the pore-forming alpha subunit and the modulatory beta subunit. The protein encoded by this gene is an auxiliary beta subunit which slows activation kinetics, leads to steeper calcium sensitivity, and shifts the voltage range of current activation to more negative potentials than does the beta 1 subunit.

Gene names and symbols associated with KCNMB4

  • potassium large conductance calcium-activated channel, subfamily M, beta member 4 (KCNMB4) 抗体
  • potassium large conductance calcium-activated channel, subfamily M, beta member 3 (Kcnmb3) 抗体
  • potassium large conductance calcium-activated channel, subfamily M, beta member 4 (kcnmb4) 抗体
  • potassium large conductance calcium-activated channel, subfamily M, beta member 4 (Kcnmb4) 抗体
  • 1700058G18Rik 抗体
  • 2900045G12Rik 抗体
  • EG435726 抗体
  • Gm5707 抗体
  • kcnmb4 抗体

Protein level used designations for KCNMB4

calcium-activated potassium channel beta 4 subunit , calcium-activated potassium channel subunit beta-4 , calcium-activated potassium channel subunit beta-3 , potassium large conductance calcium-activated channel, subfamily M, beta member 4 , BK channel subunit beta-4 , BKbeta4 , calcium-activated potassium channel, subfamily M subunit beta-4 , charybdotoxin receptor subunit beta-4 , hbeta4 , k(VCA)beta-4 , large conductance calcium-dependent potassium ion channel beta 4 subunit , maxi K channel subunit beta-4 , slo-beta-4 , Slowpoke beta 4 , calcium activated potassium channel beta 4 subunit

GENE ID SPECIES
417852 Gallus gallus
435726 Mus musculus
549965 Xenopus (Silurana) tropicalis
742962 Pan troglodytes
27345 Homo sapiens
58802 Mus musculus
66016 Rattus norvegicus
100154587 Sus scrofa
520448 Bos taurus
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