Potassium Large Conductance Calcium-Activated Channel, Subfamily M, beta Member 1 (KCNMB1) ELISA试剂盒

MaxiK channels are large conductance, voltage and calcium-sensitive potassium channels which are fundamental to the control of smooth muscle tone and neuronal excitability. 再加上,我们可以发KCNMB1 抗体 (43)KCNMB1 蛋白 (5)和数多这个蛋白质的别的产品。

list all ELISA KIts 基因 基因ID UniProt
小鼠 KCNMB1 KCNMB1 16533 Q8CAE3
 KCNMB1 KCNMB1 3779 Q16558
大鼠 KCNMB1 KCNMB1 29747 P97678

适于 KCNMB1 相互作用对的更多 ELISA 试剂盒

Mouse (Murine) Potassium Large Conductance Calcium-Activated Channel, Subfamily M, beta Member 1 (KCNMB1) interaction partners

  1. 7-Ketocholesterol induces the reduction of KCNMB1 through the AhR pathway.

  2. BK channel (显示 KCNMA1 ELISA试剂盒) activity directly affects vascular tone but influences blood pressure independent of this effect via different pathways

  3. up-regulation of NF-kappaB (显示 NFKB1 ELISA试剂盒)-dependent MuRF1 (显示 TRIM63 ELISA试剂盒) expression is a novel mechanism that leads to BK channelopathy and vasculopathy in diabetes

  4. Our results support a model whereby subcellular anchoring of CaN by AKAP150 (显示 AKAP5 ELISA试剂盒) is a key molecular determinant of vascular BKCa (显示 KCNMA1 ELISA试剂盒) channel remodeling, which contributes to vasoconstriction during diabetes mellitus.

  5. The activity of BKbeta1 is higher in cerebral smooth muscle cells compared to pulmonary artery.

  6. BK channels play a prominent role in smooth muscle function only in the distal colon of mice. Defects in smooth muscle BK channel (显示 KCNMA1 ELISA试剂盒) function disrupt colonic motility causing constipation.

  7. Impaired sodium excretion resulting form loss of normal purinergic regulation of ENaC (显示 SCNN1A ELISA试剂盒) in BK-beta4 null mice likely contributes to their elevated blood pressure

  8. these results suggested that oxidative stress inhibited Akt (显示 AKT1 ELISA试剂盒) signaling and facilitated the FOXO (显示 FOXO3 ELISA试剂盒)-3a/FBXO-dependent BK-beta(1) degradation in diabetic vessels.

  9. Reduced vascular BK channel (显示 KCNMA1 ELISA试剂盒) function does not protect against hypotension in the early stage of septic shock; in the later stage, smooth muscle BK channel (显示 KCNMA1 ELISA试剂盒) deficiency enhances organ damage and mortality

  10. BKbeta4 (显示 KCNMB4 ELISA试剂盒) and to a lesser degree BKbeta1 transcripts and protein are detected in several astrocytic populations and cultured cells.

Human Potassium Large Conductance Calcium-Activated Channel, Subfamily M, beta Member 1 (KCNMB1) interaction partners

  1. These results provide further insights into the mechanism of modulation of the different N-terminal regions of the BKCa (显示 KCNMA1 ELISA试剂盒) channel by beta-subunits.

  2. By introducing lanthanide binding tags in the extracellular region of the alpha- or beta1-subunit, we determined (i) a basic extracellular map of the BK channel (显示 KCNMA1 ELISA试剂盒), (ii) beta1-subunit-induced rearrangements of the voltage sensor in alpha-subunits, and (iii) the relative position of the beta1-subunit within the alpha/beta1-subunit complex.

  3. The study demonstrates that both transmembrane domains of BKbeta1 are required to provide the characteristic ion current phenotype of beta1-containing BK channels.

  4. Data show that two lysine residues that are unique to the N terminus of calcium-activated potassium channel subunit beta-1 were identified to be sufficient for voltage-sensor modulation.

  5. To determine the relationship between atherosclerosis and KCNMB1, we studied some atherogenic factors affecting vascular tone. Blood of atherosclerotic patients shows increased concentration of 7-ketocholesterol, possibly a harmful lipid to blood vessels.

  6. N-terminal isoforms of the large-conductance Ca(2 (显示 CA2 ELISA试剂盒))-activated K channel (显示 KCNC4 ELISA试剂盒) are differentially modulated by the auxiliary beta1-subunit.

  7. HIF-1alpha (显示 HIF1A ELISA试剂盒) increases KCNMB1 expression in response to hypoxia in human pulmonary artery smooth muscle cells by binding to two hypoxia response elements located at -3,540 to -3,311 of the KCNMB1 promoter

  8. Here we found that KCNMB1 common variant Glu65Lys influences glomerular filtration rate across multiple populations of different clinical characteristics and biogeographic ancestries.

  9. downregulation of vascular BK-beta(1) expression in diabetes and in high-glucose culture conditions was associated with FOXO (显示 FOXO3 ELISA试剂盒)-3a/FBXO-dependent increase in BK-beta(1) degradation.

  10. The expressed hSloalpha + beta1 subunit complex demonstrated to be fully functional for its typical single-channel traces, Ca(2 (显示 CA2 ELISA试剂盒)+)-sensitivity, voltage-dependency, high conductance (151 +/- 7 pS), and its pharmacological activation and inhibition.

Pig (Porcine) Potassium Large Conductance Calcium-Activated Channel, Subfamily M, beta Member 1 (KCNMB1) interaction partners

  1. The study verified that the BK(Ca) channel alpha-subunit (显示 POLG ELISA试剂盒) is located to smooth muscle cells of porcine basilar and middle cerebral arteries.

KCNMB1 抗原简介

Antigen Summary

MaxiK channels are large conductance, voltage and calcium-sensitive potassium channels which are fundamental to the control of smooth muscle tone and neuronal excitability. MaxiK channels can be formed by 2 subunits: the pore-forming alpha subunit and the product of this gene, the modulatory beta subunit. Intracellular calcium regulates the physical association between the alpha and beta subunits.

Gene names and symbols associated with KCNMB1

  • potassium large conductance calcium-activated channel, subfamily M, beta member 1 (KCNMB1) 抗体
  • potassium large conductance calcium-activated channel, subfamily M, beta member 1 (Kcnmb1) 抗体
  • BKBETA 抗体
  • BKbeta1 抗体
  • hbeta1 抗体
  • hslo-beta 抗体
  • K(VCA)beta 抗体
  • k(VCA)beta-1 抗体
  • KCNMB1 抗体
  • SLO-BETA 抗体
  • slo-beta-1 抗体

Protein level used designations for KCNMB1

calcium-activated potassium channel subunit beta-1 , calcium-activated potassium channel beta subunit , potassium large conductance calcium-activated channel, subfamily M, beta member 1 , BK channel beta subunit , BK channel subunit beta-1 , BKbeta , calcium-activated potassium channel subunit beta , calcium-activated potassium channel, subfamily M subunit beta-1 , charybdotoxin receptor subunit beta-1 , k(VCA)beta-1 , maxi K channel subunit beta-1 , slo-beta , slo-beta-1 , large conductance Ca2+-activated K+ channel beta 1 subunit , BKbeta1 , slowpoke-beta , calcium activated potassium channel beta subunit , calcium activated potassium channel beta subunit protein , calcium dependent potassium channel beta subunit protein , large conductance Ca2+-activated K+ channel beta1 subunit , large conductance calcium-activated potassium channel beta subunit , large conductance calcium-activated potassium channel beta1 subunit , maxi-K channel beta subunit

GENE ID SPECIES
395301 Gallus gallus
462258 Pan troglodytes
16533 Mus musculus
3779 Homo sapiens
29747 Rattus norvegicus
407176 Bos taurus
403983 Canis lupus familiaris
100009034 Oryctolagus cuniculus
100271876 Sus scrofa
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