Potassium Inwardly-Rectifying Channel, Subfamily J, Member 1 (KCNJ1) ELISA试剂盒

Potassium channels are present in most mammalian cells, where they participate in a wide range of physiologic responses. 再加上,我们可以发Potassium Inwardly-Rectifying Channel, Subfamily J, Member 1 抗体 (88)Potassium Inwardly-Rectifying Channel, Subfamily J, Member 1 蛋白 (14)和数多这个蛋白质的别的产品。

list all ELISA KIts 基因 基因ID UniProt
 KCNJ1 KCNJ1 3758 P48048
大鼠 KCNJ1 KCNJ1 24521 P35560
小鼠 KCNJ1 KCNJ1 56379 O88335

适于 Potassium Inwardly-Rectifying Channel, Subfamily J, Member 1 相互作用对的更多 ELISA 试剂盒

Cow (Bovine) Potassium Inwardly-Rectifying Channel, Subfamily J, Member 1 (KCNJ1) interaction partners

  1. The findings support ROMK as the pore-forming subunit of the cytoprotective mitoK(ATP) channel in heart mitochondria.

Human Potassium Inwardly-Rectifying Channel, Subfamily J, Member 1 (KCNJ1) interaction partners

  1. Data suggest underlying pathology for some patients with type II Bartter syndrome is linked to stability of ROMK1 in ERAD pathway; using a yeast expression system, cells can be rescued by wild-type (rat) ROMK1 but not by ROMK1 containing any one of four mutations found in (human) type II Bartter syndrome; mutant ROMKs are significantly less stable than wild-type ROMK. (ERAD = endoplasmic reticulum-associated degradation)

  2. WNK4 (显示 WNK4 ELISA试剂盒) is a substrate of SFKs and the association of c-Src (显示 SRC ELISA试剂盒) and PTP-1D (显示 PTPN11 ELISA试剂盒) with WNK4 (显示 WNK4 ELISA试剂盒) at Tyr (显示 TYR ELISA试剂盒)(1092) and Tyr (显示 TYR ELISA试剂盒)(1143) plays an important role in modulating the inhibitory effect of WNK4 (显示 WNK4 ELISA试剂盒) on ROMK

  3. knockdown of KCNJ1 in HK-2 (显示 HK2 ELISA试剂盒) cells promoted cell proliferation. Collectively, these data highlight that KCNJ1, low-expressed in ccRCC and associated with poor prognosis, plays an important role in ccRCC cell growth and metastasis

  4. The association between polymorphisms in KCNJ1, SLC12A1 (显示 SLC12A1 ELISA试剂盒), and 7 other genes and calcium intake and colorectal neoplasia risk was studied.

  5. A KCNJ1 SNP was associated with increased FG during HCTZ treatment.

  6. Molecular analysis revealed a compound heterozygous mutation in the KCNJ1 gene, consisting of a novel K76E and an already described V315G mutation, both affecting functional domains of the channel protein.

  7. Findings suggest that 11q24 is a susceptible locus for openness, with KCNJ1 as the possible candidate gene.

  8. no mutation in the KCNJ1 gene, among patients suffering from bartter and Gitelman syndromes

  9. PI3K (显示 PIK3CA ELISA试剂盒)-activating hormones inhibit ROMK by enhancing its endocytosis via a mechanism that involves phosphorylation of WNK1 (显示 WNK1 ELISA试剂盒) by Akt1 (显示 AKT1 ELISA试剂盒) and SGK1 (显示 SGK1 ELISA试剂盒).

  10. THGP (显示 UMOD ELISA试剂盒) modulation of ROMK function confers a new role of THGP (显示 UMOD ELISA试剂盒) on renal ion transport and may contribute to salt wasting observed in FJHN/MCKD-2 (显示 UMOD ELISA试剂盒)/GCKD patients.

Mouse (Murine) Potassium Inwardly-Rectifying Channel, Subfamily J, Member 1 (KCNJ1) interaction partners

  1. The results provide evidence that NHERF1 (显示 SLC9A3R2 ELISA试剂盒) mediates K(+) current activity through acceleration of the surface expression of ROMK1 K(+) channels in M-1 cells.

  2. ENaC (显示 SCNN1A ELISA试剂盒) and ROMK channel activity in kidney tubules are inhibited in TgWnk4(pseudoaldosteronism type II) mice. Wnk4 (显示 WNK4 ELISA试剂盒)(PHAII)-induced inhibition of ENaC (显示 SCNN1A ELISA试剂盒) and ROMK may contribute to the suppression of K(+) secretion in the tubules.

  3. The differential regulation of ROMK, large-conductance Ca(2 (显示 CA2 ELISA试剂盒)+)-activated K(+) (BK) channel (显示 KCNMA1 ELISA试剂盒), BK-alpha and NKCC2 (显示 SLC12A1 ELISA试剂盒) between female and male mice, at least, were partly mediated via WNK1 (显示 WNK1 ELISA试剂盒) pathway, which may contribute to the sexual dimorphism of plasma K(+) and blood pressure control.

  4. Suggest that the hyperkalemia in knock-in mouse with the CUL3 (显示 CUL3 ELISA试剂盒)(Delta403-459) mutation is not caused by reduced ROMK expression in the distal nephron.

  5. animal knockouts of ROMK1 do not produce Bartter phenotype. ROMK1 is critical in response to high K intake-stimulated K+ secretion in the collecting tubule.

  6. Lovastatin stimulates ROMK1 channels by inducing PI(4,5)P2 synthesis, suggesting that the drug could reduce cyclosporine-induced nephropathy.

  7. ROMK1 protein abundance and activity are down-regulated by SPAK (显示 STK39 ELISA试剂盒) and OSR1 (显示 OSR1 ELISA试剂盒)

  8. It was concluded that miR (显示 MLXIP ELISA试剂盒)-194 regulates ROMK channel activity by modulating ITSN1 (显示 ITSN1 ELISA试剂盒) expression thereby enhancing ITSN1 (显示 ITSN1 ELISA试剂盒)/WNK-dependent endocytosis.

  9. THGP (显示 UMOD ELISA试剂盒) modulation of ROMK function confers a new role of THGP (显示 UMOD ELISA试剂盒) on renal ion transport and may contribute to salt wasting observed in FJHN/MCKD-2 (显示 UMOD ELISA试剂盒)/GCKD patients.

  10. hypertension resistance sequence variants inhibit ROMK channel function by different mechanisms

Zebrafish Potassium Inwardly-Rectifying Channel, Subfamily J, Member 1 (KCNJ1) interaction partners

  1. Kcnj1 is expressed in cells associated with osmoregulation and acts as a K+ efflux pathway that is important in maintaining extracellular levels of potassium ion in the developing embryo.

Potassium Inwardly-Rectifying Channel, Subfamily J, Member 1 (KCNJ1) 抗原简介

Antigen Summary

Potassium channels are present in most mammalian cells, where they participate in a wide range of physiologic responses. The protein encoded by this gene is an integral membrane protein and inward-rectifier type potassium channel. It is activated by internal ATP and probably plays an important role in potassium homeostasis. The encoded protein has a greater tendency to allow potassium to flow into a cell rather than out of a cell. Mutations in this gene have been associated with antenatal Bartter syndrome, which is characterized by salt wasting, hypokalemic alkalosis, hypercalciuria, and low blood pressure. Multiple transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with KCNJ1

  • potassium inwardly-rectifying channel, subfamily J, member 1 (KCNJ1) 抗体
  • potassium inwardly-rectifying channel, subfamily J, member 1 (kcnj1) 抗体
  • potassium inwardly-rectifying channel, subfamily J, member 15 (kcnj15) 抗体
  • potassium inwardly-rectifying channel, subfamily J, member 1 (Kcnj1) 抗体
  • potassium inwardly-rectifying channel, subfamily J, member 1a, tandem duplicate 1 (kcnj1a.1) 抗体
  • Kcnj 抗体
  • kcnj1 抗体
  • kir1.1 抗体
  • MGC68935 抗体
  • ROMK 抗体
  • romk1 抗体
  • Romk2 抗体
  • wu:fl37c05 抗体
  • zgc:63534 抗体

Protein level used designations for KCNJ1

potassium inwardly-rectifying channel, subfamily J, member 1 , spliced potassium channels ROM-K1, ROM-K2, ROM-K3, ROM-K4, ROM-K5 and ROM-K6 , potassium inwardly-rectifying channel J1 , ATP-sensitive inward rectifier potassium channel 1 , ATP-sensitive inward rectifier potassium channel 1-like , potassium inwardly-rectifying channel, subfamily J, member 15 , ATP-regulated potassium channel ROM-K , inward rectifier K(+) channel Kir1.1 , inwardly rectifying K+ channel , potassium channel, inwardly rectifying subfamily J member 1 , K+ channel protein , KAB-1 , Potassium inwardly-rectifying channel subfamily J , kir1.1 , inwardly rectifying potassium channel ROMK-2

GENE ID SPECIES
281882 Bos taurus
428236 Gallus gallus
466846 Pan troglodytes
539250 Bos taurus
714848 Macaca mulatta
100072580 Equus caballus
100173141 Pongo abelii
100470569 Ailuropoda melanoleuca
100487609 Xenopus (Silurana) tropicalis
100517668 Sus scrofa
100556003 Anolis carolinensis
100579741 Nomascus leucogenys
379692 Xenopus laevis
3758 Homo sapiens
24521 Rattus norvegicus
56379 Mus musculus
447262 Xenopus laevis
489285 Canis lupus familiaris
386933 Danio rerio
您还需要查找其他产品吗?