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Phosphatidylinositol Binding clathrin Assembly Protein 抗体

(Phosphatidylinositol Binding clathrin Assembly Protein (PICALM))
This gene encodes a clathrin assembly protein, which recruits clathrin and adaptor protein complex 2 (AP2) to cell membranes at sites of coated-pit formation and clathrin-vesicle assembly. The protein may be required to determine the amount of membrane to be recycled, possibly by regulating the size of the clathrin cage. The protein is involved in AP2-dependent clathrin-mediated endocytosis at the neuromuscular junction. A chromosomal translocation t(10\;11)(p13\;q14) leading to the fusion of this gene and the MLLT10 gene is found in acute lymphoblastic leukemia, acute myeloid leukemia and malignant lymphomas. The polymorphisms of this gene are associated with the risk of Alzheimer disease. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2011].
PICALM 抗体  (AA 517-624) PICALM 抗体  (AA 517-624) PICALM 抗体 (AA 517-624) (ABIN7163230)

PICALM 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated

PICALM 抗体  (AA 420-646) PICALM 抗体  (AA 420-646) PICALM 抗体 (AA 420-646) (ABIN1501903)

PICALM 适用: 人 WB 宿主: 兔 Polyclonal unconjugated

PICALM 抗体  (AA 251-350) PICALM 抗体  (AA 251-350) PICALM 抗体 (AA 251-350) (ABIN1385889)

PICALM 适用: 小鼠, 大鼠 WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro), ICC 宿主: 兔 Polyclonal unconjugated

Phosphatidylinositol Binding clathrin Assembly Protein 抗体 by 适用

Find Phosphatidylinositol Binding clathrin Assembly Protein 抗体 for a variety of species such as anti-Mouse Phosphatidylinositol Binding clathrin Assembly Protein, anti-Rat Phosphatidylinositol Binding clathrin Assembly Protein, anti-Human Phosphatidylinositol Binding clathrin Assembly Protein. The species listed below are among those available. Click on a link to go to the corresponding products.

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Find Phosphatidylinositol Binding clathrin Assembly Protein 抗体 validated for a specific application such as WB, IF (cc), IF (p), ELISA. Some of the available applications are listed below. Click on a link to go to the corresponding products.

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Find Phosphatidylinositol Binding clathrin Assembly Protein 抗体 with a specific conjugate such as FITC, Biotin, HRP. The conjugates listed below are among those available. Click on a link to go to the corresponding products.

Popular Phosphatidylinositol Binding clathrin Assembly Protein 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application ELISA, IHC, IF
Validations
  • (3)
Cat. No. ABIN7163230
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB
Validations
  • (2)
Cat. No. ABIN1501903
Quantity 100 μL
Datasheet Datasheet
Reactivity Mouse, Rat
Application WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro), ICC
Validations
  • (1)
Cat. No. ABIN1385889
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB
Validations
  • (1)
Cat. No. ABIN6244061
Quantity 400 μL
Datasheet Datasheet
Reactivity Human
Application WB
Validations
  • (1)
Cat. No. ABIN6244060
Quantity 200 μL
Datasheet Datasheet
Reactivity Human
Application WB
Validations
  • (1)
Cat. No. ABIN521836
Quantity 50 μg
Datasheet Datasheet

Application WB
Validations
  • (1)
Cat. No. ABIN6748480
Quantity 100 μL
Datasheet Datasheet

Application WB
Validations
  • (1)
Cat. No. ABIN6748479
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC, IHC (p)
Validations
  • (1)
Cat. No. ABIN1960181
Quantity 50 μL
Datasheet Datasheet
Reactivity Human
Application WB
Validations
  • (1)
Cat. No. ABIN6145606
Quantity 100 μL
Datasheet Datasheet
Reactivity Mouse, Rat
Application WB, ELISA, IHC (p), IHC (fro)
Validations
Cat. No. ABIN1392613
Quantity 100 μL
Datasheet Datasheet
Reactivity Mouse, Rat
Application WB, IF (cc), IF (p)
Validations
Cat. No. ABIN1392609
Quantity 100 μL
Datasheet Datasheet
Reactivity Mouse, Rat
Application WB, IF (cc), IF (p)
Validations
Cat. No. ABIN1392610
Quantity 100 μL
Datasheet Datasheet
Reactivity Mouse, Rat
Application WB, IF (cc), IF (p)
Validations
Cat. No. ABIN1392611
Quantity 100 μL
Datasheet Datasheet
Reactivity Mouse, Rat
Application WB, IF (cc), IF (p)
Validations
Cat. No. ABIN2805326
Quantity 100 μL
Datasheet Datasheet

Latest Publications for our Phosphatidylinositol Binding clathrin Assembly Protein 抗体

Hu, Wu, Feng, Li, Wang, Qi, Du: "Cellular protein profiles altered by PRRSV infection of porcine monocytes-derived dendritic cells." in: Veterinary microbiology, Vol. 228, pp. 134-142, (2019) (PubMed).

Tsai-Teng, Chin-Chu, Li-Ya, Wan-Ping, Chung-Kuang, Chien-Chang, Chi-Ying, Chien-Chih, Shiao: "Erinacine A-enriched Hericium erinaceus mycelium ameliorates Alzheimer's disease-related pathologies in APPswe/PS1dE9 transgenic mice." in: Journal of biomedical science, Vol. 23, Issue 1, pp. 49, (2016) (PubMed).

Thomas, Henson, Gerrish, Jones, Williams, Kidd: "Decreasing the expression of PICALM reduces endocytosis and the activity of β-secretase: implications for Alzheimer's disease." in: BMC neuroscience, Vol. 17, Issue 1, pp. 50, (2016) (PubMed).

Zhao, Sagare, Ma, Halliday, Kong, Kisler, Winkler, Ramanathan, Kanekiyo, Bu, Owens, Rege, Si, Ahuja, Zhu, Miller, Schneider, Maeda, Maeda, Sugawara, Ichida, Zlokovic: "Central role for PICALM in amyloid-β blood-brain barrier transcytosis and clearance." in: Nature neuroscience, Vol. 18, Issue 7, pp. 978-87, (2015) (PubMed).

Mercer, Argus, Crabtree, Keenan, Wilks, Chi, Bensinger, Lavau, Wechsler: "Modulation of PICALM Levels Perturbs Cellular Cholesterol Homeostasis." in: PLoS ONE, Vol. 10, Issue 6, pp. e0129776, (2015) (PubMed).

Armstrong, Mattsson, Appelqvist, Janefjord, Sandin, Agholme, Olsson, Svensson, Blennow, Zetterberg, Kågedal: "Lysosomal network proteins as potential novel CSF biomarkers for Alzheimer's disease." in: Neuromolecular medicine, Vol. 16, Issue 1, pp. 150-60, (2014) (PubMed).

Aliases for Phosphatidylinositol Binding clathrin Assembly Protein 抗体

leucine aminopeptidase 3 (LAP3) 抗体
phosphatidylinositol binding clathrin assembly protein (PICALM) 抗体
phosphatidylinositol binding clathrin assembly protein (Picalm) 抗体
si:ch211-200p22.4 (si:ch211-200p22.4) 抗体
CALM 抗体
Calm 抗体
CLTH 抗体
fit-1 抗体
fit1 抗体
LAP 抗体
LAP-3 抗体
mKIAA4114 抗体
PAP180 抗体
PEPS 抗体
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