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PES1 encodes a nuclear protein that contains a breast cancer associated gene 1 (BRCA1) C-terminal interaction domain. 再加上，我们可以发PES1 抗体 (38) 和 PES1 蛋白 (5)和数多这个蛋白质的别的产品。
These data suggest that PES1 is a marker of neuroblastoma (显示 ARHGEF16 ELISA试剂盒) outcome, that it regulates neuroblastoma (显示 ARHGEF16 ELISA试剂盒) cell proliferation, and is associated with neuroblastoma (显示 ARHGEF16 ELISA试剂盒) differentiation.
Data show that pescadillo associates with several structures that are associated with nucleogenesis, and that loss of function results in embryonic lethality due to disrupted ribosome biosynthesis.
effects of PES1 and UBF1 (显示 UBTF ELISA试剂盒) expression on the growth and differentiation of cell lines derived from 32D cells, an interleukin-3 (IL-3 (显示 IL-3 ELISA试剂盒))-dependent murine myeloid cell line
Interaction with Bop1 (显示 BOP1 ELISA试剂盒) is essential for the efficient incorporation of Pes1 into nucleolar preribosomal complexes.
Mechanisms for the ability of Pes1 to transform cells, and its failure to immortalize them.
Mtap1b (显示 MAP1B ELISA试剂盒)-Light chain 1 has the potential to repress cell proliferation by modulating the nucleolar levels of Pes1
PES1 may play an important role in development of gastric cancer.
The DDX27 (显示 DDX27 ELISA试剂盒) can interact specifically with the Pes1 and Bop1 (显示 BOP1 ELISA试剂盒) but fulfils critical function(s) for proper 3' end formation of 47S rRNA independently of the PeBoW-complex.
PES1 may play important role in the progression of ovarian cancer by inversely regulating the ERalpha (显示 ESR1 ELISA试剂盒) and ERbeta (显示 ESR2 ELISA试剂盒) expression.
these results uncover a potential role of PES1 in chemoresistance by regulating DNA damage response in colorectal cancer cells.
Upstream of c-Jun (显示 JUN ELISA试剂盒), it was revealed that c-Jun (显示 JUN ELISA试剂盒) NH2-terminal kinases (JNK (显示 MAPK8 ELISA试剂盒)) is essential for controlling PES1 expression
expression of PES1 correlated positively with ERalpha (显示 ESR1 ELISA试剂盒) expression and negatively with ERbeta (显示 ESR2 ELISA试剂盒) expression and predicted good clinical outcome in breast cancer
The physical interaction between B23 (显示 NPM1 ELISA试剂盒) and PES1 implies that they may participate in ribosome biogenesis in a protein complex.
pescadillo might play a role in promoting the proliferation and carcinogenesis of human breast cancer, and thereby might be a potential target for human breast cancer treatment.
RRB1 (显示 GRWD1 ELISA试剂盒) interacts with YPH1 (yeast pescadillo homologue 1) and other members of the Yph1 complex
pes1 and ppan (显示 PPAN ELISA试剂盒) are required for Xenopus pronephros development and indicate that their function in the pronephros is independent of their role in ribosome biosynthesis
pescadillo has multiple important functions during X. laevis development; pescadillo is required for eye development and neural crest migration
This gene encodes a nuclear protein that contains a breast cancer associated gene 1 (BRCA1) C-terminal interaction domain. The encoded protein interacts with BOP1 and WDR12 to form the PeBoW complex, which plays a critical role in cell proliferation via pre-rRNA processing and 60S ribosomal subunit maturation. Expression of this gene may play an important role in breast cancer proliferation and tumorigenicity. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. Pseudogenes of this gene are located on the long arm of chromosome 4 and the short arm of chromosome 9.
, pescadillo homolog 1, containing BRCT domain