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PNPLA8 encodes a member of the patatin-like phospholipase domain containing protein family. 再加上，我们可以发Patatin-Like phospholipase Domain Containing 8 抗体 (38) 和 Patatin-Like phospholipase Domain Containing 8 蛋白 (3)和数多这个蛋白质的别的产品。
iPLA2gamma plays an important role in in vivo Thromboxane A2 production accompanied by thrombus formation.
iPLA2gamma plays a cardioprotective role during the acute stage of Chagas' disease.
Thus, complement-mediated activation of iPLA(2)gamma is mediated via ERK (显示 EPHB2 ELISA试剂盒) and p38 (显示 CRK ELISA试剂盒) pathways, and phosphorylation of Ser (显示 SIGLEC1 ELISA试剂盒)-511 and/or Ser (显示 SIGLEC1 ELISA试剂盒)-515 plays a key role in the catalytic activity and signaling of iPLA(2)gamma.
These results suggest distinct roles for iPLA2beta (显示 PLA2G6 ELISA试剂盒) and iPLA2gamma in cellular homeostasis and signaling, a functional link between peroxisomal AA release and eicosanoid generation, and a potential contribution of iPLA2gamma to tumorigenesis.
iPLA2 (显示 PLA2G6 ELISA试剂盒) activation is not sufficient for SOCE activation. iPLA2 (显示 PLA2G6 ELISA试剂盒) may regulate basal phosphoinositide metabolism
these results demonstrate the integrated roles of Cardiolipin and iPLA2gamma in lipid second-messenger production and mitochondrial bioenergetics during oxidative stress.
Because mitochondrial membrane depolarization and calcium are known to activate iPLA2gamma, these results are consistent with salvage of myocardium after Ischemia/Reperfusion by iPLA2gamma loss of function through decreasing mPTP (显示 PTPN2 ELISA试剂盒) opening, diminishing production of proinflammatory oxidized fatty acids
UCP2 (显示 UCP2 ELISA试剂盒), functional due to fatty acids released by redox-activated mt-iPLA2gamma, suppresses mitochondrial superoxide production by its uncoupling action.
Mitochondrial dysfunction and reduced prostaglandin synthesis in skeletal muscle of Group VIB (显示 SEMA6B ELISA试剂盒) Ca2 (显示 CA2 ELISA试剂盒)+-independent phospholipase A2gamma-deficient mice
iPLA(2)beta (显示 PLA2G6 ELISA试剂盒) and iPLA(2 (显示 PLA2G6 ELISA试剂盒))gamma are required for the adipogenic program that drives resting 3T3-L1 cells into adipocytes after hormone stimulation
iPLA2 (显示 PLA2G6 ELISA试剂盒) signaling plays an important role in glucose-stimulated insulin (显示 INS ELISA试剂盒) secretion under physiological conditions
iPLA(2 (显示 PLA2G6 ELISA试剂盒))gamma is essential for maintaining efficient bioenergetic mitochondrial function through tailoring mitochondrial membrane lipid metabolism and composition
the obligatory role of iPLA(2 (显示 PLA2G6 ELISA试剂盒))gamma in neuronal mitochondrial lipid metabolism and membrane structure demonstrating that iPLA(2 (显示 PLA2G6 ELISA试剂盒))gamma loss of function results in a mitochondrial neurodegenerative disorder
This gene encodes a member of the patatin-like phospholipase domain containing protein family. Members of this family are phospholipases which catalyze the cleavage of fatty acids from membrane phospholipids. The product of this gene is a calcium-independent phospholipase. A pseudogene of this gene is located on the X chromosome. Multiple transcript variants encoding different isoforms have been found for this gene.
, calcium-independent phospholipase A2-gamma
, iPLA2 gamma
, intracellular membrane-associated calcium-independent phospholipase A2 gamma
, membrane-associated calcium-independent phospholipase A2 gamma
, patatin-like phospholipase domain-containing protein 8
, group VIB calcium-independent phospholipase A2