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PANK2 抗体

(Pantothenate Kinase 2 (PANK2))
This gene encodes a protein belonging to the pantothenate kinase family and is the only member of that family to be expressed in mitochondria. Pantothenate kinase is a key regulatory enzyme in the biosynthesis of coenzyme A (CoA) in bacteria and mammalian cells. It catalyzes the first committed step in the universal biosynthetic pathway leading to CoA and is itself subject to regulation through feedback inhibition by acyl CoA species. Mutations in this gene are associated with HARP syndrome and pantothenate kinase-associated neurodegeneration (PKAN), formerly Hallervorden-Spatz syndrome. Alternative splicing, involving the use of alternate first exons, results in multiple transcripts encoding different isoforms. [provided by RefSeq, Jul 2008].
PANK2 抗体 PANK2 抗体 PANK2 抗体 (ABIN1500026)

PANK2 适用: 人, 大鼠, 犬, 猴 WB, IHC, IF, IHC (p), FACS 宿主: 小鼠 Monoclonal 3H9 unconjugated

PANK2 抗体  (AA 437-490) PANK2 抗体  (AA 437-490) PANK2 抗体 (AA 437-490) (ABIN7162603)

PANK2 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated

PANK2 抗体  (AA 205-260) PANK2 抗体  (AA 205-260) PANK2 抗体 (AA 205-260) (ABIN566414)

PANK2 适用: 人 WB, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 2B12 unconjugated

PANK2 抗体 by 适用

Find PANK2 抗体 for a variety of species such as anti-Human PANK2, anti-Mouse PANK2, anti-Rat PANK2. The species listed below are among those available. Click on a link to go to the corresponding products.

PANK2 抗体 by 应用范围

Find PANK2 抗体 validated for a specific application such as WB, ELISA, IF (cc), IF (p). Some of the available applications are listed below. Click on a link to go to the corresponding products.

PANK2 抗体 by 抗体来源

Find PANK2 抗体 with a specific 抗体来源. The 抗体来源 listed below are among those available. Click on a link to go to the corresponding products.

PANK2 抗体 by 抗原表位

Find PANK2 抗体 with a specific epitope. The epitopes listed below are among those available. Click on a link to go to the corresponding products.

PANK2 抗体 by 克隆形成能力

Find available monoclonal or polyclonal PANK2 抗体. Click on a link to go to the corresponding products.

PANK2 抗体 by 克隆

Find PANK2 抗体 with a specific 克隆. The 克隆 listed below are among those available. Click on a link to go to the corresponding products.

PANK2 抗体 by 标记

Find PANK2 抗体 with a specific conjugate such as FITC, Biotin, HRP. The conjugates listed below are among those available. Click on a link to go to the corresponding products.

Popular PANK2 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Dog, Human, Monkey, Rat
Application WB, IHC, IF, IHC (p), FACS
Validations
  • (8)
Cat. No. ABIN1500026
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IHC, IF
Validations
  • (3)
Cat. No. ABIN7162603
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IHC (p)
Validations
  • (3)
Cat. No. ABIN566414
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB
Validations
  • (3)
  • (1)
Cat. No. ABIN543681
Quantity 400 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IF, ICC
Validations
  • (1)
Cat. No. ABIN6264029
Quantity 100 μL
Datasheet Datasheet
Reactivity Bat, Cow, Dog, Horse, Human, Pig, Rat, Sheep
Application WB
Validations
  • (1)
Cat. No. ABIN6748470
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB
Validations
  • (1)
Cat. No. ABIN7269169
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IF, FACS
Validations
  • (2)
Cat. No. ABIN2728204
Quantity 0.1 mL
Datasheet Datasheet
Reactivity Mouse
Application WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro)
Validations
Cat. No. ABIN1386810
Quantity 100 μL
Datasheet Datasheet
Reactivity Mouse
Application WB, ELISA, IHC (p), IHC (fro)
Validations
Cat. No. ABIN1398505
Quantity 100 μL
Datasheet Datasheet
Reactivity Mouse
Application WB, IF (cc), IF (p)
Validations
Cat. No. ABIN1398501
Quantity 100 μL
Datasheet Datasheet
Reactivity Mouse
Application WB, IF (cc), IF (p)
Validations
Cat. No. ABIN1398502
Quantity 100 μL
Datasheet Datasheet
Reactivity Mouse
Application WB, IF (cc), IF (p)
Validations
Cat. No. ABIN2805063
Quantity 100 μL
Datasheet Datasheet
Reactivity Mouse
Application WB, IF (cc), IF (p)
Validations
Cat. No. ABIN1398503
Quantity 100 μL
Datasheet Datasheet
Reactivity Mouse
Application WB, IF (cc), IF (p)
Validations
Cat. No. ABIN5008315
Quantity 100 μL
Datasheet Datasheet

Latest Publications for our PANK2 抗体

Santambrogio, Dusi, Guaraldo, Rotundo, Broccoli, Garavaglia, Tiranti, Levi: "Mitochondrial iron and energetic dysfunction distinguish fibroblasts and induced neurons from pantothenate kinase-associated neurodegeneration patients." in: Neurobiology of disease, (2015) (PubMed).

Huang, Chu, Jiang, Chen, Zhang, Zeng: "Glycyrrhizin suppresses lung adenocarcinoma cell growth through inhibition of thromboxane synthase." in: Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, Vol. 33, Issue 2, pp. 375-88, (2014) (PubMed).

Zeman, Lin, Freire, Cimprich: "DNA damage-specific deubiquitination regulates Rad18 functions to suppress mutagenesis." in: The Journal of cell biology, Vol. 206, Issue 2, pp. 183-97, (2014) (PubMed).

Barrett, Fang, Gargano, Markovich, Kocarek, Runge-Morris: "Regulation of murine hepatic hydroxysteroid sulfotransferase expression in hyposulfatemic mice and in a cell model of 3'-phosphoadenosine-5'-phosphosulfate deficiency." in: Drug metabolism and disposition: the biological fate of chemicals, Vol. 41, Issue 8, pp. 1505-13, (2013) (PubMed).

Brunetti, Dusi, Morbin, Uggetti, Moda, DAmato, Giordano, dAmati, Cozzi, Levi, Hayflick, Tiranti: "Pantothenate kinase-associated neurodegeneration: altered mitochondria membrane potential and defective respiration in Pank2 knock-out mouse model." in: Human molecular genetics, Vol. 21, Issue 24, pp. 5294-305, (2012) (PubMed).

Hörtnagel, Prokisch, Meitinger: "An isoform of hPANK2, deficient in pantothenate kinase-associated neurodegeneration, localizes to mitochondria." in: Human molecular genetics, Vol. 12, Issue 3, pp. 321-7, (2003) (PubMed).

Houlden, Lincoln, Farrer, Cleland, Hardy, Orrell: "Compound heterozygous PANK2 mutations confirm HARP and Hallervorden-Spatz syndromes are allelic." in: Neurology, Vol. 61, Issue 10, pp. 1423-6, (2003) (PubMed).

Ching, Westaway, Gitschier, Higgins, Hayflick: "HARP syndrome is allelic with pantothenate kinase-associated neurodegeneration." in: Neurology, Vol. 58, Issue 11, pp. 1673-4, (2002) (PubMed).

Aliases for PANK2 抗体

pantothenate kinase 2 (PANK2) 抗体
pantothenate kinase 2 (Tsp_01576) 抗体
pantothenate kinase 2, mitochondrial (LOC100539295) 抗体
pantothenate kinase 2 (Pank2) 抗体
ribonuclease A family member 11 (inactive) (RNASE11) 抗体
4933409I19Rik 抗体
AI642621 抗体
ATPANK2 抗体
C20orf48 抗体
F10M6.180 抗体
F10M6_180 抗体
HARP 抗体
HSS 抗体
NBIA1 抗体
PANK2 抗体
pantothenate kinase 2 抗体
PKAN 抗体
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