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PYCARD 蛋白

(PYD and CARD Domain Containing (PYCARD))
This gene encodes an adaptor protein that is composed of two protein-protein interaction domains: a N-terminal PYRIN-PAAD-DAPIN domain (PYD) and a C-terminal caspase-recruitment domain (CARD). The PYD and CARD domains are members of the six-helix bundle death domain-fold superfamily that mediates assembly of large signaling complexes in the inflammatory and apoptotic signaling pathways via the activation of caspase. In normal cells, this protein is localized to the cytoplasm\; however, in cells undergoing apoptosis, it forms ball-like aggregates near the nuclear periphery. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].
PYCARD Protein (AA 1-149) (GST tag) PYCARD Protein (AA 1-149) (GST tag) PYCARD Protein (AA 1-149) (GST tag) (ABIN1316968)

PYCARD 宿主: 人 宿主: 小麦胚 Recombinant ELISA, WB, AP, AA

PYCARD Protein (AA 1-195) (His tag) PYCARD Protein (AA 1-195) (His tag) PYCARD Protein (AA 1-195) (His tag) (ABIN3089316)

Crystallography grade PYCARD 宿主: 人 宿主: 大肠杆菌(E. Coli) Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, WB, Crys, SDS

PYCARD Protein (AA 1-193) (His tag) PYCARD Protein (AA 1-193) (His tag) PYCARD Protein (AA 1-193) (His tag) (ABIN3137154)

Crystallography grade PYCARD 宿主: 小鼠 宿主: 大肠杆菌(E. Coli) Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, WB, Crys, SDS

PYCARD 蛋白 by Grade

Find PYCARD 蛋白 with a specific Grade. The Grade listed below are among those available. Click on a link to go to the corresponding products.

PYCARD 蛋白 by Origin

Find PYCARD 蛋白 for a variety of species such as anti-Human PYCARD, anti-Cow PYCARD, anti-Mouse PYCARD. The species listed below are among those available. Click on a link to go to the corresponding products.

PYCARD 蛋白 by Source

Here you will find PYCARD 蛋白 proteins organized by several key sources. By clicking on a link, you can access the products. For additional sources, please use our search function.

PYCARD 蛋白 by 蛋白类型

Here you can find PYCARD 蛋白 proteins categorized by available protein types. Additional protein types can be located using our search function.

PYCARD 蛋白 by 应用范围

Find PYCARD 蛋白 validated for a specific application such as ELISA, AbP, STD, WB. Some of the available applications are listed below. Click on a link to go to the corresponding products.

Popular PYCARD 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
  • (1)
Cat. No. ABIN1316968
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN3089316
Quantity 1 mg
Datasheet Datasheet
Reactivity Mouse
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN3137154
Quantity 1 mg
Datasheet Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (1)
Cat. No. ABIN2713165
Quantity 20 μg
Datasheet Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (1)
Cat. No. ABIN2730218
Quantity 20 μg
Datasheet Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (1)
Cat. No. ABIN2713166
Quantity 20 μg
Datasheet Datasheet
Reactivity Cow
Source Yeast
Validations
Cat. No. ABIN1636486
Quantity 1 mg
Datasheet Datasheet
Reactivity Zebrafish (Danio rerio)
Source Yeast
Validations
Cat. No. ABIN1646663
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our PYCARD 蛋白

Shi, Wang, Li, Zhan, Tang, Fina, Su, Pratt, Bu, Hildebrand, Lyon, Scott, Quan, Sun, Russell, Arnett, Jurek, Chen, Kravchenko, Mathison, Moresco, Monson, Ulevitch, Beutler: "NLRP3 activation and mitosis are mutually exclusive events coordinated by NEK7, a new inflammasome component." in: Nature immunology, Vol. 17, Issue 3, pp. 250-8, (2016) (PubMed).

Aliases for PYCARD 蛋白

PYD and CARD domain containing (PYCARD) 蛋白
PYD and CARD domain containing (Pycard) 蛋白
PYD and CARD domain containing (pycard) 蛋白
9130417A21Rik 蛋白
ASC 蛋白
Asc 蛋白
asc1 蛋白
CARD5 蛋白
masc 蛋白
TMS 蛋白
TMS-1 蛋白
TMS1 蛋白
TNS1 蛋白
zAsc 蛋白
zgc:109874 蛋白
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