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PRDM6 蛋白

(PR Domain Containing 6 (PRDM6))
Putative histone methyltransferase that acts as a transcriptional repressor of smooth muscle gene expression. Promotes the transition from differentiated to proliferative smooth muscle by suppressing differentiation and maintaining the proliferative potential of vascular smooth muscle cells. Also plays a role in endothelial cells by inhibiting endothelial cell proliferation, survival and differentiation. It is unclear whether it has histone methyltransferase activity in vivo. According to some authors, it does not act as a histone methyltransferase by itself and represses transcription by recruiting EHMT2/G9a. According to others, it possesses histone methyltransferase activity when associated with other proteins and specifically methylates 'Lys-20' of histone H4 in vitro. 'Lys-20' methylation represents a specific tag for epigenetic transcriptional repression (By similarity).
PRDM6 Protein (AA 1-595) (Strep Tag) PRDM6 Protein (AA 1-595) (Strep Tag) PRDM6 Protein (AA 1-595) (Strep Tag) (ABIN3094724)

Crystallography grade PRDM6 宿主: 人 宿主: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, SDS, WB

PRDM6 Protein (AA 1-596) (Strep Tag) PRDM6 Protein (AA 1-596) (Strep Tag) PRDM6 Protein (AA 1-596) (Strep Tag) (ABIN3135115)

Crystallography grade PRDM6 宿主: 小鼠 宿主: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, SDS, WB

PRDM6 蛋白 by Grade

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PRDM6 蛋白 by Origin

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PRDM6 蛋白 by Source

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PRDM6 蛋白 by 蛋白类型

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PRDM6 蛋白 by 应用范围

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Popular PRDM6 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Tobacco (Nicotiana tabacum)
Validations
  • (1)
Cat. No. ABIN3094724
Quantity 1 mg
Datasheet Datasheet
Reactivity Mouse
Source Tobacco (Nicotiana tabacum)
Validations
  • (1)
Cat. No. ABIN3135115
Quantity 1 mg
Datasheet Datasheet

Aliases for PRDM6 蛋白

PR/SET domain 6 (PRDM6) 蛋白
PR domain containing 6 (Prdm6) 蛋白
PR/SET domain 6 (Prdm6) 蛋白
putative histone-lysine N-methyltransferase PRDM6 (LOC100354345) 蛋白
PR domain containing 6 (prdm6) 蛋白
Gm92 蛋白
PRDM6 蛋白
PRISM 蛋白
RGD1559594 蛋白
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