POC1 Centriolar Protein Homolog B (Chlamydomonas) 蛋白 (POC1B)

Required for ciliogenesis (By similarity).. 再加上,我们可以发POC1B 抗体 (34)和数多这个蛋白质的别的产品。

列出全部蛋白 基因 基因ID UniProt
POC1B 282809 Q8TC44
POC1B 382406 Q8BHD1
POC1B    
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Insect Cells 小鼠 His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 60 Days
$7,759.50
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Insect Cells His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 60 Days
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小麦胚 GST tag 10 μg Log in to see 11至12个工作日
$405.71
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HEK-293 Cells Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Log in to see 10至12个工作日
$785.40
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酵母菌 斑马鱼 His tag   1 mg Log in to see 60至71个工作日
$3,386.17
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POC1B 蛋白 by Origin and Source

Origin 在表达 标记
Human , ,
, ,
Mouse (Murine)

Zebrafish (Danio rerio)

更多POC1 Centriolar Protein Homolog B (Chlamydomonas) (POC1B)互动伙伴

Human POC1 Centriolar Protein Homolog B (Chlamydomonas) (POC1B) interaction partners

  1. Depletion of CEP295 blocks the incorporation of POC5 (显示 POC5 蛋白) and POC1B into the distal portion of centrioles and suppresses the post-translational modification of centriolar microtubules . Our study thus uncovers a new role for CEP295 during centriole elongation.

  2. Intronic SNP in POC1B/GALNT4 (显示 GALNT4 蛋白) locus (rs11105306) was associated with NT-proBNP levels in patients with acute coronary syndrome (ACS (显示 PLA2G15 蛋白)). The POC1B/GALNT4 (显示 GALNT4 蛋白) SNP was not associated with higher risk of cardiovascular death.

  3. Study found that homozygous POC1B mutation, i.e., c.737C --> T(p.T246 M), cosegregated with the phenotype of a tested family, indicating that POC1B gene was the most possible pathogenic gene for paroxysmal kinesigenic dyskinesia

  4. Study indicates that POC1B is required for retinal integrity, and is proposed POC1B mutations as a probable cause for Joubert syndrome with severe polycystic kidney disease.

  5. POC1B is a novel gene for a new disease typical of cone-rod dystrophy except that patients did not report night blindness.

  6. POC1B mutations result in a defect of the photoreceptor sensory cilium and thus affect cone and rod photoreceptors.

  7. Poc1A (显示 POC1A 蛋白) and Poc1B play redundant, but essential, roles in generation of stable centrioles, but Poc1B may have additional independent functions during cell cycle progression.

  8. Poc1B is required for primary ciliogenesis; Poc1 provides a molecular link between the assembly and stability of centrioles for ciliary-based motility in T. thermophila and cilia formation and function in zebrafish and humans

  9. Based on these data, we propose that Pix1 and Pix2 (显示 POC1A 蛋白) are microtubule-associated adaptor proteins that likely contribute to a range of developmental and cell division processes.

Zebrafish POC1 Centriolar Protein Homolog B (Chlamydomonas) (POC1B) interaction partners

  1. data suggest that poc1b is required for normal development and ciliogenesis of retinal photoreceptor sensory cilia and other cilia

  2. Poc1B knockdown causes ciliary defects & morphological phenotype consistent with ciliopathies; Poc1 provides link between assembly & stability of centrioles for ciliary-based motility in Tetrahymena & cilia formation & function in D rerio & humans

蛋白简介POC1B

蛋白简介

Required for ciliogenesis (By similarity).

Gene names and symbols associated with POC1B

  • POC1 centriolar protein B (POC1B)
  • POC1 centriolar protein B (Poc1b)
  • POC1 centriolar protein B (poc1b)
  • 4933430F16Rik 蛋白
  • fl36w17 蛋白
  • PIX1 蛋白
  • TUWD12 蛋白
  • wdr51b 蛋白
  • wu:fl36w17 蛋白
  • zgc:63538 蛋白

Protein level used designations for POC1B

POC1 centriolar protein homolog B , WD repeat-containing protein 51B , WD repeat domain 51B

GENE ID SPECIES
282809 Homo sapiens
382406 Mus musculus
386932 Danio rerio
POC1B 蛋白 (POC1B) 精选生产商
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