anti-Oligonucleotide/oligosaccharide-Binding Fold Containing 1 (OBFC1) 抗体

OBFC1 and C17ORF68 (MIM 613129) are subunits of an alpha accessory factor (AAF) that stimulates the activity of DNA polymerase-alpha-primase (see MIM 176636), the enzyme that initiates DNA replication (Casteel et al., 2009. 再加上,我们可以发Oligonucleotide/oligosaccharide-Binding Fold Containing 1 蛋白 (13)Oligonucleotide/oligosaccharide-Binding Fold Containing 1 试剂盒 (5)和数多这个蛋白质的别的产品。

列出全部抗体 基因 基因ID UniProt
OBFC1 79991 Q9H668
OBFC1 108689 Q8K2X3
OBFC1 294025 Q6AYD2
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antibodies-online.cn销售最多的anti-Oligonucleotide/oligosaccharide-Binding Fold Containing 1 抗体

Showing 10 out of 48 products:

产品编号 适用 宿主 标记 应用范围 图像 规格 供应商 交付 价格 详细
Cow 非结合性 WB WB Suggested Anti-OBFC1 Antibody Titration: 1.0 ug/ml Positive Control: Fetal Heart 100 μL Log in to see 2至3个工作日
$289.00
详细
非结合性 EIA, WB Western blot analysis of OBFC1 Antibody (C-term) in A549 cell line lysates (35ug/lane). This demonstrates the OBFC1 antibody detected the OBFC1 protein (arrow). 0.4 mL Log in to see 6至8个工作日
$390.50
详细
小鼠 非结合性 WB OBFC1 monoclonal antibody (M01), clone 3G12-1B7 Western Blot analysis of OBFC1 expression in Jurkat. 0.1 mg Log in to see 8至11个工作日
$450.00
详细
非结合性 WB 50 μg Log in to see 7至9个工作日
$551.83
详细
小鼠 非结合性 FACS, IF, WB HEK293T cells transfected with either RC200778 overexpress plasmid (Red) or empty vector control plasmid (Blue) were immunostained by anti-OBFC1 antibody (ABIN2454844), and then analyzed by flow cytometry. Anti-OBFC1 mouse monoclonal antibody (ABIN2454844) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY OBFC1 (RC200778). 100 μL Log in to see 2至3个工作日
$423.50
详细
小鼠 非结合性 ELISA, WB OBFC1 monoclonal antibody (M01), clone 3G12-1B7 Western Blot analysis of OBFC1 expression in Jurkat . Western Blot detection against Immunogen (66.22 KDa) . 100 μg Log in to see 11至12个工作日
$430.00
详细
非结合性 WB OBFC1 Antibody (C-term)  western blot analysis in A549 cell line lysates (35ug/lane).This demonstrates the OBFC1 antibody detected the OBFC1 protein (arrow). 400 μL Log in to see 10至11个工作日
$324.50
详细
小鼠 非结合性 FACS, ICC, IF, WB Immunocytochemistry/Immunofluorescence: OBFC1 Antibody (2E4) [NBP2-01006] Staining of COS7 cells transiently transfected by pCMV6-ENTRY OBFC1. Western Blot: OBFC1 Antibody (2E4) [NBP2-01006] - HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY OBFC1 (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-OBFC1. 0.1 mL Log in to see 8至11个工作日
$447.56
详细
小鼠 非结合性 FACS, IF, WB 100 μL Log in to see 7至9个工作日
$529.83
详细
非结合性 IF, IP, WB Immunoprecipitation of OBFC1 transfected lysate using anti-OBFC1 MaxPab rabbit polyclonal antibody and Protein A Magnetic Bead , and immunoblotted with OBFC1 purified MaxPab mouse polyclonal antibody (B01P) . Western Blot analysis of OBFC1 expression in transfected 293T cell line by OBFC1 MaxPab polyclonal antibody.<br><br>Lane 1: OBFC1 transfected lysate(42.1 KDa).<br>Lane 2: Non-transfected lysate.<br> 100 μL Log in to see 11至12个工作日
$418.57
详细

通过反应活性、应用领域、克隆类型和共轭标记 OBFC1 抗体

特性 应用范围 宿主 克隆类型 标记
Human
,
,
, , , , ,
Mouse (Murine)


Rat (Rattus)


引用最多的anti-Oligonucleotide/oligosaccharide-Binding Fold Containing 1 抗体

  1. Yeast (Saccharomyces cerevisiae) Polyclonal OBFC1 Primary Antibody for - ABIN967112 : Grandin, Reed, Charbonneau: Stn1, a new Saccharomyces cerevisiae protein, is implicated in telomere size regulation in association with Cdc13. in Genes & development 1997 (PubMed)
    Show all 5 Pubmed References

  2. Yeast (Saccharomyces cerevisiae) Polyclonal OBFC1 Primary Antibody for IHC - ABIN967111 : Coster, Jonniaux, Goffeau: Analysis of a 32.8 kb segment of yeast chromosome IV reveals 21 open reading frames, including TPS2, PPH3, RAD55, SED1, PDC2, AFR1, SSS1, SLU7 and a tRNA for arginine. in Yeast (Chichester, England) 1995 (PubMed)
    Show all 5 Pubmed References

  3. Human Monoclonal OBFC1 Primary Antibody for ELISA, WB - ABIN566413 : Wan, Qin, Songyang, Liu: OB fold-containing protein 1 (OBFC1), a human homolog of yeast Stn1, associates with TPP1 and is implicated in telomere length regulation. in The Journal of biological chemistry 2009 (PubMed)

更多抗Oligonucleotide/oligosaccharide-Binding Fold Containing 1的相互作用对抗体

Human Oligonucleotide/oligosaccharide-Binding Fold Containing 1 (OBFC1) interaction partners

  1. CTC1 (显示 CTC1 抗体)/STN1 (显示 STON1 抗体)/TEN1 (CST (显示 GAL3ST1 抗体)) deficiency diminishes HU-induced RAD51 (显示 RAD51 抗体) foci formation.

  2. STN1 (显示 STON1 抗体)-POLA2 (显示 POLA2 抗体) interaction provides a basis for primase-polymerase alpha stimulation by human STN1 (显示 STON1 抗体). A disease-causing mutation in human STN1 (显示 STON1 抗体) engenders a selective defect in POLA2 (显示 POLA2 抗体)-binding.

  3. The findings imply that theCTC1/STN1/TEN1 complex(CST )complex plays an important role in regulating telomere maintenance in alternative-lengthening of telomeres(ALT) cells.

  4. TERT-mediated G-strand extension and Ctc1-Stn1-Ten1-mediated C-strand fill-in are equally important for telomere length maintenance.

  5. Mutations in STN1 (显示 STON1 抗体) cause Coats plus syndrome and are associated with genomic and telomere defects.

  6. The mammalian CST (显示 GAL3ST1 抗体) (CTC1 (显示 CTC1 抗体)-STN1 (显示 STON1 抗体)-TEN1) complex is directly involved at several stages of telomere end formation and CST (显示 GAL3ST1 抗体) seems to play critical roles in coordinating telomerase elongation and fill-in synthesis to telomere replication.

  7. we explored two SNPs in genes associated either with telomere biology (OBFC1) or with LTL (OBCF1 and CTC1 (显示 CTC1 抗体)). Interestingly, we observed that genetic variation does not account for LTL at birth

  8. A 2-SNP OBFC1 haplotype was associated with higher risk of CHD (显示 CHDH 抗体), and a 3-SNP TERC haplotype was associated with both higher risk of CHD (显示 CHDH 抗体) and T2D.

  9. The Stn1 deficiency leads to persistent and elevated association of DNA polymerase alpha to telomeres, suggesting that Stn1 may modulate the DNA synthesis activity of polalpha rather than controlling the loading of polalpha to telomeres.

  10. the requirement for STN1 (显示 STON1 抗体)/CST (显示 GAL3ST1 抗体) in telomere duplex replication correlates with increasing telomere length and replication stress.

Mouse (Murine) Oligonucleotide/oligosaccharide-Binding Fold Containing 1 (OBFC1) interaction partners

  1. OBFC1 is identical to the previously described 44 kDa subunit of DNA-pol-alpha/primase associated factor (AAF) which increases polymerase-alpha/primase template affinity and stimulate both DNA primase and polymerase-alpha activities in vitro.

Arabidopsis thaliana Oligonucleotide/oligosaccharide-Binding Fold Containing 1 (OBFC1) interaction partners

  1. STN1 plays a genome-wide role in DNA replication and telomere stability.

  2. POT1a promotes an extendable telomere state via contacts with the telomerase RNP as well as STN1 and CTC1, while TEN1 opposes these functions.

  3. findings indicate that ATR and CST (CTC1/STN1/TEN1) act synergistically to maintain genome integrity and telomere length homeostasis

  4. AtSTN1 is a crucial component of the protective telomere cap in Arabidopsis, and likely in other multicellular eukaryotes. (AtSTN1)

  5. CTC1 (显示 CTC1 抗体) participates in telomere maintenance in diverse species and that a CST (显示 GAL3ST1 抗体)-like complex is required for telomere integrity in multicellular organisms.

Oligonucleotide/oligosaccharide-Binding Fold Containing 1 (OBFC1) 抗原简介

蛋白简介

OBFC1 and C17ORF68 (MIM 613129) are subunits of an alpha accessory factor (AAF) that stimulates the activity of DNA polymerase-alpha-primase (see MIM 176636), the enzyme that initiates DNA replication (Casteel et al., 2009

Gene names and symbols associated with OBFC1

  • STN1, CST complex subunit (STN1) 抗体
  • STN1, CST complex subunit (Stn1) 抗体
  • STN1, CST complex subunit (stn1) 抗体
  • Nucleic acid-binding, OB-fold-like protein (STN1) 抗体
  • 0610009H20Rik 抗体
  • 2310057J23Rik 抗体
  • AAF-44 抗体
  • AAF44 抗体
  • AI413458 抗体
  • ATSTN1 抗体
  • bA541N10.2 抗体
  • F10K1.17 抗体
  • F10K1_17 抗体
  • RP11-541N10.2 抗体
  • RPA-32 抗体
  • STN1 抗体
  • zgc:64174 抗体

Protein level used designations for OBFC1

CST complex subunit STN1 , alpha accessory factor 44 , oligonucleotide/oligosaccharide-binding fold-containing protein 1 , replication protein A 32 kDa subunit , suppressor of cdc thirteen homolog , alpha-accessory factor of 44 kDa

GENE ID SPECIES
79991 Homo sapiens
108689 Mus musculus
294025 Rattus norvegicus
514213 Bos taurus
393360 Danio rerio
837223 Arabidopsis thaliana
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