ORM1-Like 3 (S. Cerevisiae) (ORMDL3) ELISA试剂盒

Negative regulator of sphingolipid synthesis. 再加上,我们可以发ORMDL3 抗体 (24)ORMDL3 蛋白 (4)和数多这个蛋白质的别的产品。

list all ELISA KIts 基因 基因ID UniProt
ORMDL3 94103 Q8N138
小鼠 ORMDL3 ORMDL3 66612 Q9CPZ6
大鼠 ORMDL3 ORMDL3 360618 Q6QI25

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3.9 pg/mL 15.6-1000 pg/mL Typical standard curve 96 Tests Log in to see 9至12个工作日
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Human ORM1-Like 3 (S. Cerevisiae) (ORMDL3) interaction partners

  1. this study demonstrated the upregulation of (显示 ATF6 ELISA试剂盒) ORMDL3 (显示 BECN1 ELISA试剂盒)in patients with systemic lupus erythematosus

  2. ORMDL3 might influence de novo sphingolipid metabolism downstream of serine palmitoyltransferase

  3. modest changes (8-13%) in promoter methylation levels of ZPBP2 (显示 ZPBP2 ELISA试剂盒) and GSDMA may cause substantial changes in RNA levels and allelic expression of ZPBP2 (显示 ZPBP2 ELISA试剂盒) and ORMDL3 is mediated by DNA methylation (显示 HELLS ELISA试剂盒)

  4. Decreased ORMDL3 expression increased levels of free sphingoid bases and sphingoid base phosphates, and also caused increases in cellular levels of ceramides.

  5. ORMDL3 overexpression is associated with asthma.

  6. The TT homozygote and the T allele of rs7216389 in ORMDL3 increased bronchiolitis risk. The rs7216389 polymorphism may be a predictor for identifying infants with predisposition to virus-induced wheezing to persistent asthma.

  7. Two single nucleotide polymorphisms regulating ORMDL3 expression (rs7216389 and rs9303277) significantly associated with atherosclerosis risk and the evidence of increased ORMDL3 expression in AS cases compared to controls.

  8. The SNP (rs7216389) of ORMDL3 does not influence the expression of OPN (显示 SPP1 ELISA试剂盒) and TGF-beta1 (显示 TGFB1 ELISA试剂盒), suggesting that it may not be associated with airway remodeling.

  9. ORMDL3 variants have been shown to be associated with Asthma in children with Rhinovirus infections -induced wheezing illnesses.

  10. The meta-analysis indicates that ORMDL3 rs7216389 may contribute to increasing susceptibility to asthma. (Meta-analysis)

Mouse (Murine) ORM1-Like 3 (S. Cerevisiae) (ORMDL3) interaction partners

  1. ORMDL3 mediates the autophagy via the ATF 6 (显示 ATF6 ELISA试剂盒)-Beclin1 (显示 BECN1 ELISA试剂盒) autophagy pathway, and it facilitates the survival of splenic B cells via promoting autophagy and suppressing apoptosis

  2. ORMDL3 might influence de novo sphingolipid metabolism downstream of serine palmitoyltransferase

  3. inhibiting ORMDL3 in airway epithelial cells plays a significant role in induction of allergen-induced increases in airway hyperresponsiveness

  4. ORMDL3, an asthma susceptibility gene identified by genome-wide association studies, contributes to key pathways that promote changes in airway physiology during allergic immune responses.

  5. Mediated by GATA3 (显示 GATA3 ELISA试剂盒) through targeting promoter region of ORMDL3.

  6. Downregulation of ORMDL3 expression in mast cells enhances AKT (显示 AKT1 ELISA试剂盒) and NF-kappaB (显示 NFKB1 ELISA试剂盒)-directed signaling pathways and chemotaxis and contributes to the development of mast cell-mediated local inflammation in vivo.

  7. overexpression of ORMDL3 regulates ceramide homeostasis in cells in a complex manner and suggest that local FTY720 administration might be a useful therapeutic intervention for the control of allergic asthma.

  8. the contribution of ORMDL3 to asthma risk may involve changes in sphingolipid metabolism

  9. These studies provide evidence that ORMDL3 plays an important role in vivo in airway remodeling potentially through ATF6 (显示 ATF6 ELISA试剂盒) target genes.

  10. ORMDL3 promotes eosinophil trafficking and activation via regulation of CD18 (显示 ITGB2 ELISA试剂盒), CD49d, and CD48 (显示 CD48 ELISA试剂盒).

ORMDL3 抗原简介

Antigen Summary

Negative regulator of sphingolipid synthesis. May indirectly regulate endoplasmic reticulum-mediated Ca(+2) signaling (By similarity).

Gene names and symbols associated with ORMDL3

  • ORM1-like 3 (S. cerevisiae) (ORMDL3) 抗体
  • ORM1-like 3 (S. cerevisiae) (Ormdl3) 抗体
  • 2810011N17Rik 抗体
  • AI315223 抗体
  • LRRGT00183 抗体

Protein level used designations for ORMDL3

ORM1-like protein 3 , liver regeneration-related protein LRRGT00183

GENE ID SPECIES
94103 Homo sapiens
66612 Mus musculus
360618 Rattus norvegicus
615368 Bos taurus
100479284 Ailuropoda melanoleuca
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