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NAMPT encodes a protein that catalyzes the condensation of nicotinamide with 5-phosphoribosyl-1-pyrophosphate to yield nicotinamide mononucleotide, one step in the biosynthesis of nicotinamide adenine dinucleotide. 再加上，我们可以发NAMPT 试剂盒 (112) 和 NAMPT 蛋白 (59)和数多这个蛋白质的别的产品。
Showing 10 out of 353 products:
Dog (Canine) Polyclonal NAMPT Primary Antibody for ICC, IF - ABIN152026
Ye, Simon, Maloney, Zambelli-Weiner, Gao, Grant, Easley, McVerry, Tuder, Standiford, Brower, Barnes, Garcia: Pre-B-cell colony-enhancing factor as a potential novel biomarker in acute lung injury. in American journal of respiratory and critical care medicine 2005
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Human Monoclonal NAMPT Primary Antibody for ICC, FACS - ABIN1169028
Bae, Kim, Kim, Kim, Koo, Jang, Yun, Yoo, Bae: Hypoxic induction of human visfatin gene is directly mediated by hypoxia-inducible factor-1. in FEBS letters 2006
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Human Polyclonal NAMPT Primary Antibody for IP - ABIN250753
Krzysik-Walker, Ocón-Grove, Maddineni, Hendricks, Ramachandran: Is visfatin an adipokine or myokine? Evidence for greater visfatin expression in skeletal muscle than visceral fat in chickens. in Endocrinology 2008
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Human Polyclonal NAMPT Primary Antibody for IHC (p), WB - ABIN652958
Samal, Sun, Stearns, Xie, Suggs, McNiece: Cloning and characterization of the cDNA encoding a novel human pre-B-cell colony-enhancing factor. in Molecular and cellular biology 1994
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Human Monoclonal NAMPT Primary Antibody for ELISA, WB - ABIN2869291
Rongvaux, Shea, Mulks, Gigot, Urbain, Leo, Andris: Pre-B-cell colony-enhancing factor, whose expression is up-regulated in activated lymphocytes, is a nicotinamide phosphoribosyltransferase, a cytosolic enzyme involved in NAD biosynthesis. in European journal of immunology 2003
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Cow (Bovine) Polyclonal NAMPT Primary Antibody for IHC, WB - ABIN2775322
Chen, Chung, Chang, Tsai, Huang, Shin, Lee: Elevated plasma level of visfatin/pre-B cell colony-enhancing factor in patients with type 2 diabetes mellitus. in The Journal of clinical endocrinology and metabolism 2006
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Human Monoclonal NAMPT Primary Antibody for EIA, IHC (p) - ABIN336072
Stephens, Vidal-Puig: An update on visfatin/pre-B cell colony-enhancing factor, an ubiquitously expressed, illusive cytokine that is regulated in obesity. in Current opinion in lipidology 2006
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Human Polyclonal NAMPT Primary Antibody for WB - ABIN223662
Gesing, Masternak, Wang, Joseph, Leeuwenburgh, Westbrook, Lewinski, Karbownik-Lewinska, Bartke: Expression of key regulators of mitochondrial biogenesis in growth hormone receptor knockout (GHRKO) mice is enhanced but is not further improved by other potential life-extending interventions. in The journals of gerontology. Series A, Biological sciences and medical sciences 2011
Visfatin increases the nuclear translocation of Akt (显示 AKT1 抗体) and its binding with ABCC1 (显示 ABCC1 抗体). These data showed that visfatin can decrease doxorubicin sensitivity of Non-small-cell lung cancer cells via activation of Akt (显示 AKT1 抗体)/MRP1 (显示 MDM4 抗体).
Results suggest a mechanism by which tumor cells protect themselves against glucose deprivation-induced oxidative stress by utilizing nicotinamide phosphoribosyltransferase (NAMPT) to maintain NADPH (显示 NQO1 抗体) levels.
The combination of upregulation of the NAD(+) de novo synthesis pathway through QPRT (显示 QPRT 抗体) over-expression and NAMPT mutation confers resistance to GMX1778, but the cells are only partially resistant to next-generation NAMPT inhibitors. The resistance mechanisms uncovered herein provide a potential avenue to continue exploration of next generation NAMPT inhibitors to treat neoplasms in the clinic.
this study shows that upstream visfatin SNPs could potentially affect phenotypic outcome in obese children through alteration of circulating visfatin level.
Lack of changes in serum visfatin level despite the changes in visfatin mRNA expression of adipose tissue suggests paracrine effect of visfatin rather than endocrine
Ascending aorta from aortic aneurysm patient,s revealed an inverse relationship between smooth muscle cell NAMPT content and aortic diameter.
Visfatin significantly correlated with BMI and hot flashes number in postmenopausal women with metabolic syndrome.
Single nucleotide polymorphism in the NAMPT gene is associated with inflammation in chronic kidney disease.
our present study revealed that visfatin is over-expressed in colorectal cancer doxorubicin-resistant cells; visfatin mediates doxorubicin resistance via upregulation of MDR1 (显示 TBC1D9 抗体)
Nampt inhibition may override gemcitabine resistance by decreasing the NAD level and suppressing glycolytic activity in pancreatic neoplasms.
role of Nampt in regulating osteoblast differentiation in primary mouse bone marrow-derived mesenchymal stem cells (BM-MSCs); Nampt expression was progressively elevated during BM-MSCs osteogenic differentiation
The results suggest that NCOA6 (显示 NCOA6 抗体) stimulates insulin (显示 INS 抗体) secretion, at least partially, by modulating Nampt expression in pancreatic beta-cells.
the protein expression levels of TIMP-2 (显示 TIMP2 抗体) and PBEF in cloned placentae, were examined.
NAMPT inhibited endothelial progenitor cell senescence through an SIRT1 (显示 SIRT1 抗体) AS lncRNA/miR (显示 MLXIP 抗体)-22/SIRT1 (显示 SIRT1 抗体) pathway
Visfatin upregulated CD36 (显示 CD36 抗体) and SRA (显示 MSR1 抗体) expression and downregulated ABCA1 (显示 ABCA1 抗体) and ABCG1 (显示 ABCG1 抗体) expression, subsequently increased ox-LDL uptake and decreased cholesterol efflux, and finally promoted foam cell formation via the PI3K- and ERK (显示 EPHB2 抗体)-dependent pathways.
results support a novel, important role for Nampt-mediated NAD(+) biosynthesis in long-term depression and in the function of GluN2B (显示 GRIN2B 抗体)-containing NMDARs
extracellular NAMPT can be actively released by melanoma cells in vitro.
We now report that NAMPT/PBEF induces lung NFkappaB transcriptional activities and inflammatory injury via direct ligation of Toll-like receptor 4 (TLR4 (显示 TLR4 抗体)).
Visfatin plays an important role in glucose metabolism via the calcium mediated AMPK (显示 PRKAA1 抗体)-p38 MAPK (显示 MAPK14 抗体) pathway.
Deacetylation of intracellular NAMPT by the mammalian NAD(+)-dependent deacetylase SIRT1 (显示 SIRT1 抗体) predisposes the protein to secretion in adipocytes.
In a wild boar x Meishan F2 family nicotinamide phosphoribosyltransferase nicotinamide phosphoribosyltransferase SNP 669T>C was associated with muscling, fat deposition, growth and fattening, meat quality and other traits.
cloning and characterization of porcine visfatin and its three alternate splicing variants is reported; sequence analysis indicated that variant 1 is the predominant form among species.
The porcine visfatin gene cannot be considered as a marker of fat accumulation since the highest visfatin expression levels were associated with the leaner (显示 CACNA1A 抗体) animals.
Exposure to follicular fluid transiently increased the transcript levels of IL8 (显示 IL8 抗体) and PTGS2 (显示 PTGS2 抗体), and decreased the expression of SOD2 (显示 SOD2 抗体), GPX3 (显示 GPX3 抗体), DAB2 (显示 DAB2 抗体), and NR3C1 (显示 NR3C1 抗体). TNF (显示 TNF 抗体) and IL6 (显示 IL6 抗体) levels were also decreased while those of NAMPT were unaffected.
the presence of 35bp-insertion in visfatin gene may influence the birth weight and bodyweight in 6-month-old cows.
These results indicate that mammary epithelial cells express the visfatin protein and secrete them into the milk.
This gene encodes a protein that catalyzes the condensation of nicotinamide with 5-phosphoribosyl-1-pyrophosphate to yield nicotinamide mononucleotide, one step in the biosynthesis of nicotinamide adenine dinucleotide. The protein belongs to the nicotinic acid phosphoribosyltransferase (NAPRTase) family and is thought to be involved in many important biological processes, including metabolism, stress response and aging. This gene has a pseudogene on chromosome 10.
pre-B-cell colony enhancing factor 1
, Nicotinamide phosphoribosyltransferase
, nicotinamide phosphoribosyltransferase
, pre-B cell-enhancing factor
, pre-B-cell colony-enhancing factor 1
, pre-B-cell colony-enhancing factor 1 homolog