anti-Neutrophil Cytosolic Factor 4, 40kDa (NCF4) 抗体

The protein encoded by NCF4 is a cytosolic regulatory component of the superoxide-producing phagocyte NADPH-oxidase, a multicomponent enzyme system important for host defense. 再加上,我们可以发Neutrophil Cytosolic Factor 4, 40kDa 蛋白 (11)和数多这个蛋白质的别的产品。

列出全部抗体 基因 基因ID UniProt
NCF4 17972 P97369
NCF4 500904  
NCF4 4689 Q15080

antibodies-online.cn销售最多的anti-Neutrophil Cytosolic Factor 4, 40kDa 抗体

Showing 10 out of 122 products:

产品编号 适用 宿主 标记 应用范围 图像 规格 供应商 交付 价格 详细
Cow 非结合性 WB WB Suggested Anti-NCF4 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:312500Positive Control: HepG2 cell lysate 100 μL Log in to see 24至29个工作日
¥3,074.65
详细
Cow 非结合性 WB 100 μL Log in to see 24至29个工作日
¥3,074.65
详细
山羊 非结合性 IHC, ELISA, WB ABIN190755 (0.5µg/ml) staining of Daudi cell lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. 100 μg Log in to see 24至29个工作日
¥9,230.97
详细
非结合性 FACS, IHC (p), WB Western blot analysis of NCF4 antibody (C-term) (ABIN391905) in K562 cell line lysates (35 µg/lane). NCF4 (arrow) was detected using the purified polyclonal antibody. Formalin-fixed and paraffin-embedded human lymphoma reacted with NCF4 Antibody (C-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. 400 μL Log in to see 5至8个工作日
¥2,325.14
详细
非结合性 WB WB Suggested Anti-NCF4 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:1562500Positive Control: Human Muscle WB Suggested Anti-NCF4  Antibody Titration: 0.2-1 µg/mL ELISA Titer: 1:1562500  Positive Control: Human Muscle 100 μL Log in to see 24至29个工作日
¥3,074.65
详细
小鼠 非结合性 ELISA Detection limit for recombinant GST tagged NCF4 is approximately 0.3 ng/mL as a capture antibody. 0.1 mg Log in to see 11至15个工作日
¥3,179.71
详细
山羊 非结合性 IHC (p), IHC, ELISA, WB ABIN253305 (0.5ug/ml) staining of Daudi cell lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. Western Blot: NCF4 Antibody [ABIN2533056] - Analysis of NCF4 antibody using ABIN2533056 at 0.01ug/ml in Daudi cell lysate (35ug protein in RIPA buffer). 0.1 mg Log in to see 25至31个工作日
¥3,333.96
详细
非结合性 IHC (p) 0.1 mg Log in to see 29至35个工作日
¥3,884.46
详细
非结合性 IHC, ELISA Immunohistochemistry analysis of paraffin-embedded human ovary, using p40 phox (Phospho-Thr154) Antibody. The picture on the right is treated with the synthesized peptide. 100 μg Log in to see 24至29个工作日
¥3,026.87
详细
山羊 非结合性 EIA, IHC (p), WB   0.1 mg Log in to see 30至37个工作日
¥3,065.96
详细

通过反应活性、应用领域、克隆类型和共轭标记 NCF4 抗体

特性 应用范围 宿主 克隆类型 标记
Mouse (Murine) , , , ,


, , , , , , , , , , , , ,
Rat (Rattus) ,


, , , , , , , , , , , , ,
Human , , , ,
, ,
,
, , , , , , , , , , , , , , , ,

引用最多的anti-Neutrophil Cytosolic Factor 4, 40kDa 抗体

  1. Human Monoclonal NCF4 Primary Antibody for ELISA - ABIN393677 : Bailey, Xie, Do, Montpetit, Diaz, Mohan, Keavney, Yusuf, Gerstein, Engert, Anand: Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study. in Diabetes Care 2010 (PubMed)
    Show all 5 references for 393677

  2. Human Polyclonal NCF4 Primary Antibody for FACS, IHC (p) - ABIN391905 : Glas, Seiderer, Pasciuto, Tillack, Diegelmann, Pfennig, Konrad, Schmechel, Wetzke, Török, Stallhofer, Jürgens, Griga, Klein, Epplen, Schiemann, Mussack, Lohse, Göke, Ochsenkühn, Folwaczny, Müller-Myhsok, Brand: rs224136 on chromosome 10q21.1 and variants in PHOX2B, NCF4, and FAM92B are not major genetic risk factors for susceptibility to Crohn's disease in the German population. in The American journal of gastroenterology 2009 (PubMed)
    Show all 2 references for 391905

  3. Human Polyclonal NCF4 Primary Antibody for IHC (p), IHC - ABIN253305 : Rioux, Xavier, Taylor, Silverberg, Goyette, Huett, Green, Kuballa, Barmada, Datta, Shugart, Griffiths, Targan, Ippoliti, Bernard, Mei, Nicolae, Regueiro, Schumm, Steinhart, Rotter, Duerr, Cho, Daly et al.: Genome-wide association study identifies new susceptibility loci for Crohn disease and implicates autophagy in disease pathogenesis. ... in Nature genetics 2007 (PubMed)

  4. Cow (Bovine) Polyclonal NCF4 Primary Antibody for WB - ABIN2782428 : Chen, He, Minshall, Dinauer, Ye: Characterization of a mutation in the Phox homology domain of the NADPH oxidase component p40phox identifies a mechanism for negative regulation of superoxide production. in The Journal of biological chemistry 2007 (PubMed)

更多抗Neutrophil Cytosolic Factor 4, 40kDa的相互作用对抗体

Mouse (Murine) Neutrophil Cytosolic Factor 4, 40kDa (NCF4) interaction partners

  1. These studies demonstrate a critical role of phosphatidylinositol 3-phosphate-p40(phox) binding for optimal activation of the NADPH oxidase (显示 NOX1 抗体) in macrophages.

  2. Our data reveal a specific role for NCF4-mediated intracellular ROS (显示 ROS1 抗体) production in regulating autoimmunity and chronic inflammation.

  3. p40phox deficiency leads to upregulation of chemokine receptor 1 (显示 CMKLR1 抗体) and downregulation of fucosyltransferases and sialyltransferases involved in glycan modifications during experimental intestinal inflammation.

  4. cooperation of p40(phox) with p47(phox) for Nox2 (显示 CYBB 抗体)-based NADPH oxidase (显示 NOX1 抗体) activation during Fcgamma receptor (FcgammaR)-mediated phagocytosis

  5. The defect in Reactive Oxygen Species production and killing of s aureus by p40(phox-/-) neutrophils defines p40(phox) as an essential component in bacterial killing.

  6. p40 (显示 LANCL1 抗体)(phoxR58A/R58A) embryos do not develop normally but p40 (显示 LANCL1 抗体)(phoxR58A/-) mice are viable and neutrophils from these animals exhibit significantly reduced oxidase responses compared to those from their p40(phox+/-) siblings.

  7. Class III PI3K Vps34 (显示 PIK3C3 抗体) is responsible for the synthesis of PtdIns(3)P on phagosomes containing either S aureus or E coli. PtdIns(3)P binding to p40(phox) is important for CD18 (显示 ITGB2 抗体)-dependent activation oxidase activation in response to S aureus and E coli

  8. p40(phox) is prephosphorylated in resting endothelial cells and can compensate p47(phox) in keeping basal ROS (显示 ROS1 抗体) production.

Human Neutrophil Cytosolic Factor 4, 40kDa (NCF4) interaction partners

  1. Phosphoinositol 3-phosphate regulates reactive oxygen species production by maintaining p40phox and p67phox (显示 NCF2 抗体) at the phagosomal membrane.

  2. NCF4 polymorphism was associated with Crohn's disease, but not ulcerative colitis in Caucasian--{REVIEW}

  3. NCF4 may induce ex- pression of NADPH oxidase (显示 NOX1 抗体) enzymes, such as p67phox (显示 NCF2 抗体), p47phox (显示 NCF1 抗体), p22phox (显示 CYBA 抗体) and NOX2 (显示 CYBB 抗体), which lead to increased ROS (显示 ROS1 抗体) levels.

  4. Germline variation in NCF4, an innate immunity gene, is associated with an increased risk of colorectal cancer.

  5. The contribution of the functionally relevant NADPH (显示 NQO1 抗体) polymorphisms rs1883112 and rs4673 to anthracycline-related heart lesions provides a plausible explanation for their modulation of cardiotoxicity.

  6. Constitutive and inducible intracellular production of reactive oxygen species (ROS (显示 ROS1 抗体)) is higher in B cells expressing functional p40phox, supporting a direct role for p40phox in regulating B cell intracellular ROS (显示 ROS1 抗体) generation.

  7. Genome-wide association studies-reported associations between the NELL1, NCF4, and FAM92B genes and susceptibility to Crohn's disease could not be replicated in Canadian children and young adults.

  8. Younger age at diagnosis, complicated disease behavior, and ileal disease location are risk factors for perianal CD. First report of an association of the NCF4 gene with perianal disease.

  9. cooperation of p40(phox) with p47(phox) for Nox2 (显示 CYBB 抗体)-based NADPH oxidase (显示 NOX1 抗体) activation during Fcgamma receptor (FcgammaR)-mediated phagocytosis

  10. Results demonstrate that PBEF (显示 NAMPT 抗体) can prime for PMN (显示 TBCE 抗体) respiratory burst activity by promoting p40 (显示 IL9 抗体) and p47 (显示 ING1 抗体) translocation to the membrane.

Cow (Bovine) Neutrophil Cytosolic Factor 4, 40kDa (NCF4) interaction partners

  1. Study proposes that NCF4 splice variants generated by functional SNP are important risk factors for mastitis susceptibility in dairy cows.

Neutrophil Cytosolic Factor 4, 40kDa (NCF4) 抗原简介

蛋白简介

The protein encoded by this gene is a cytosolic regulatory component of the superoxide-producing phagocyte NADPH-oxidase, a multicomponent enzyme system important for host defense. This protein is preferentially expressed in cells of myeloid lineage. It interacts primarily with neutrophil cytosolic factor 2 (NCF2/p67-phox) to form a complex with neutrophil cytosolic factor 1 (NCF1/p47-phox), which further interacts with the small G protein RAC1 and translocates to the membrane upon cell stimulation. This complex then activates flavocytochrome b, the membrane-integrated catalytic core of the enzyme system. The PX domain of this protein can bind phospholipid products of the PI(3) kinase, which suggests its role in PI(3) kinase-mediated signaling events. The phosphorylation of this protein was found to negatively regulate the enzyme activity. Alternatively spliced transcript variants encoding distinct isoforms have been observed.

Gene names and symbols associated with NCF4

  • p40phox protein (p40phox) 抗体
  • neutrophil cytosolic factor 4 (LOC100136241) 抗体
  • neutrophil cytosolic factor 4 (Ncf4) 抗体
  • neutrophil cytosolic factor 4, 40kDa (NCF4) 抗体
  • AI451400 抗体
  • NCF 抗体
  • P40PHOX 抗体
  • SH3PXD4 抗体

Protein level used designations for NCF4

p40phox protein , neutrophil cytosolic factor 4 , NADPH oxidase cytosolic protein p40phox , NCF-4 , neutrophil NADPH oxidase factor 4 , neutrophil cytosol factor 4 , p40-phox , SH3 and PX domain-containing protein 4

GENE ID SPECIES
445891 Takifugu rubripes
100136241 Oncorhynchus mykiss
17972 Mus musculus
500904 Rattus norvegicus
4689 Homo sapiens
481277 Canis lupus familiaris
507859 Bos taurus
100009359 Oryctolagus cuniculus
anti-Neutrophil Cytosolic Factor 4, 40kDa (NCF4) 抗体 精选生产商
您还需要查找其他产品吗?