anti-Neutrophil Cytosolic Factor 1 (NCF1) 抗体

The protein encoded by NCF1 is a 47 kDa cytosolic subunit of neutrophil NADPH oxidase.

列出全部抗体 基因 基因ID UniProt
小鼠 NCF1 NCF1 17969 Q09014
 NCF1 NCF1 653361 P14598

更多抗Neutrophil Cytosolic Factor 1的相互作用对抗体

Mouse (Murine) Neutrophil Cytosolic Factor 1 (NCF1) interaction partners

  1. The authors demonstrated a significant role of the host NADPH oxidase (显示 NOX1 抗体) in promoting chronic inflammatory pathology in the oviduct following chlamydial infection.

  2. data partly explains the discrepancy of the phenotypes reported earlier utilizing the Ncf1m1J mice or Ncf1 knockout mice.

  3. Data (including data from studies in transgenic mice) suggest that ability to generate Ncf1-derived superoxide, specifically in CD4 (显示 CD4 抗体)-positive T-lymphocytes, is key for development of autoimmune responses in type 1 diabetes.

  4. The Park7 (显示 PARK7 抗体) binds to p47(phox), a subunit of the NADPH oxidase (显示 NOX1 抗体), to promote NADPH oxidase (显示 NOX1 抗体)-dependent production of ROS (显示 ROS1 抗体).

  5. p47(phox)-dependent NADPH (显示 FDXR 抗体) oxidases are a major glomerular source of reactive oxygen species, contributing to kidney injury

  6. p47phox mRNA expression was increased in diet-induced obese (DIO) mice. p47phox suppresses collateral vessel growth after femoral artery ligation in DIO mice.

  7. These findings suggest that a p47(phox)-dependent NAD(P)H (显示 NQO1 抗体) oxidase mediates the increase in diaphragm oxidants and contractile dysfunction in chronic heart failure.

  8. The present study provides evidence that augmented EGFRtk impairs vascular function by NADPH oxidase (显示 NOX1 抗体)-dependent mechanism. Therefore, EGFRtk and oxidative stress should be potential targets to treat vascular dysfunction in TD2.

  9. NOX2 (显示 CYBB 抗体)/ROS (显示 ROS1 抗体) activity in macrophages signals the development of antigen-specific CD8 (显示 CD8A 抗体)(+)T cell response.

  10. p47phox plays a critical role in the regulation of adventitial fibroblast proliferation and migration and may be a new therapeutic target for neointimal hyperplasia

Human Neutrophil Cytosolic Factor 1 (NCF1) interaction partners

  1. Decreased and increased copy numbers of NCF1 predispose to and protect against SLE.

  2. Lysophosphatidylcholines prime polymorphonuclear neutrophil through Hck (显示 HCK 抗体)-dependent activation of PKCdelta (显示 PKCd 抗体), which stimulates PKCgamma (显示 PRKCG 抗体), resulting in translocation of phosphorylated p47(phox).

  3. There was an increased frequency of the NCF1-339 T allele in patients with systemic lupus erythematosus. The NCF1-339 T allele reduced extracellular ROS (显示 ROS1 抗体) production in neutrophils and led to an increase expression of type 1 interferon (显示 IFNA 抗体)-regulated genes.

  4. Skeletal muscle protein expression of the NADPH oxidase (显示 NOX1 抗体) subunits p22(phox (显示 CYBA 抗体)), p47(phox), and p67(phox (显示 NCF2 抗体)) was increased in obese relative to lean subjects, where p22(phox (显示 CYBA 抗体)) and p67(phox (显示 NCF2 抗体)) expression was attenuated by exercise training in obese subjects.

  5. A novel role for Spns2 (显示 SPNS2 抗体) and S1P1 (显示 S1PR1 抗体)&2 in the activation of p47(phox) and production of reactive oxygen species involved in hyperoxia-mediated lung injury.

  6. Study provides evidence for a novel PKC-zeta (显示 PRKCZ 抗体) to p47phox interaction that is required for cell transformation from blebbishields and ROS (显示 ROS1 抗体) production in cancer cells.

  7. Overexpression of p47phox is associated with increased migration/metastasis rate in melanoma.

  8. A rare mutation in NCF1 encoding p47phox of the leukocyte NADPH oxidase (显示 NOX1 抗体) causes lack of superoxide generation, leads to chronic granulomatous disease and was recently (1200-2300 years ago) introduced into the Kavkazi Jewish population

  9. Data show that diphenylene iodonium (DPI (显示 DSP 抗体)) and apocynin can reduce hyperoxia-induced reactive oxygen species (ROS (显示 ROS1 抗体)) production by decreasing the translocation and level of NADPH Oxidase (显示 NOX1 抗体) p47phox.

  10. increased levels of gp91phox (显示 CYBB 抗体), p47phox and p22phox (显示 CYBA 抗体) likely account for the interferon-gamma (显示 IFNG 抗体) mediated enhancement of dimethyl sulfoxide-induced Nox2 (显示 CYBB 抗体) activity.

Cow (Bovine) Neutrophil Cytosolic Factor 1 (NCF1) interaction partners

  1. Differential Roles of Protein Complexes NOX1 (显示 NOX1 抗体)-NOXO1 (显示 NOXO1 抗体) and NOX2 (显示 CYBB 抗体)-p47phox in Mediating Endothelial Redox Responses to Oscillatory and Unidirectional Laminar Shear Stress.

  2. two novel splice variants designed as NCF1-TV1 (retained intron 6) and NCF1-TV2 (retained part of intron 8)encoding two putative truncated proteins (239AA and 283AA). Two splice variants were up-regulated in the mastitis-infected cows' mammary tissues, blood and neutrophils compared with these of healthy cows.

  3. A p47(phox) and Src kinase (显示 CSK 抗体) activation of peroxide production by Nox2 (显示 CYBB 抗体) appears to be an important contributor to vascular contractile mechanisms mediated through activation of protein kinase C (显示 PKC 抗体).

Neutrophil Cytosolic Factor 1 (NCF1) 抗原简介


The protein encoded by this gene is a 47 kDa cytosolic subunit of neutrophil NADPH oxidase. This oxidase is a multicomponent enzyme that is activated to produce superoxide anion. Mutations in this gene have been associated with chronic granulomatous disease.

Gene names and symbols associated with NCF1

  • neutrophil cytosolic factor 1 (p47phox) 抗体
  • general transcription factor IIi (GTF2I) 抗体
  • neutrophil cytosolic factor 1 (Ncf1) 抗体
  • neutrophil cytosolic factor 1 (NCF1) 抗体
  • neutrophil cytosolic factor 1 (ncf1) 抗体
  • cb893 抗体
  • Ncf-1 抗体
  • NCF1A 抗体
  • NOXO2 抗体
  • p47 抗体
  • p47phox 抗体
  • SH3PXD1A 抗体

Protein level used designations for NCF1

neutrophil cytosolic factor 1 , 47 kDa neutrophil oxidase factor , NADPH oxidase subunit (47 kD) , NADPH oxidase subunit (47kDa) , NCF-47K , neutrophil NADPH oxidase factor 1 , neutrophil cytosol factor 1 , p47-phox , 47 kDa autosomal chronic granulomatous disease protein , NADPH oxidase organizer 2 , NCF-1 , SH3 and PX domain-containing protein 1A , neutrophil cytosolic factor 1, (chronic granulomatous disease, autosomal 1) , nox organizer 2 , nox-organizing protein 2 , neutrophil cytosolic factor 1 (47kDa, chronic granulomatous disease, autosomal 1) , p47phox

619225 Ciona intestinalis
100227162 Taeniopygia guttata
17969 Mus musculus
653361 Homo sapiens
281345 Bos taurus
378966 Danio rerio