Neutral Sphingomyelinase (N-SMase) Activation Associated Factor (NSMAF) ELISA试剂盒

NSMAF encodes a WD-repeat protein that binds the cytoplasmic sphingomyelinase activation domain of the 55kD tumor necrosis factor receptor. 再加上,我们可以发Neutral Sphingomyelinase (N-SMase) Activation Associated Factor 抗体 (50)Neutral Sphingomyelinase (N-SMase) Activation Associated Factor 蛋白 (5)和数多这个蛋白质的别的产品。

list all ELISA KIts 基因 基因ID UniProt
NSMAF 8439 Q92636
NSMAF 18201 O35242
大鼠 NSMAF NSMAF 353233  

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0.054 ng/mL 0.15-10 ng/mL 96 Tests Log in to see 7至10个工作日
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适于 Neutral Sphingomyelinase (N-SMase) Activation Associated Factor 相互作用对的更多 ELISA 试剂盒

Human Neutral Sphingomyelinase (N-SMase) Activation Associated Factor (NSMAF) interaction partners

  1. The interaction of FAN with receptor for activated C-kinase 1 (RACK1 (显示 GNB2L1 ELISA试剂盒)) appears to be dependent on the folding of the WD repeats into a secondary structure, because no linear binding motifs are identified in the WD-repeat region of FAN.

  2. sphingolipid activator proteins like domain may stabilize the fold of acid sphingomyelinase (显示 SMPD1 ELISA试剂盒)

  3. Regulation of NSMAF by TNF-alpha (显示 TNF ELISA试剂盒) involves PRKCD (显示 PKCd ELISA试剂盒) in lung epithelial cells.

Mouse (Murine) Neutral Sphingomyelinase (N-SMase) Activation Associated Factor (NSMAF) interaction partners

  1. FAN through promoting melanoma cellular motility and tumour invasiveness is critical for the tumour-promoting action of tumor necrosis factor (显示 TNF ELISA试剂盒).

  2. FAN is not implicated in the development of methionine and choline deficient diet-induced non-alcoholic steatohepatitis.

  3. the role of FAN and IL-6 (显示 IL6 ELISA试剂盒) in the inflammatory response initiated by endotoxin, implicating TNFalpha (显示 TNF ELISA试剂盒)

  4. FAN mediates activation of N-SMase as well as regulation of lysosome size by signaling pathways that operate independent from activation/membrane recruitment of PKC.

  5. The results of this study suggest that PH-mediated plasma membrane targeting of FAN is critically involved in tumor necrosis factor (显示 TNF ELISA试剂盒)-induced Cdc42 (显示 CDC42 ELISA试剂盒) activation and cytoskeleton reorganization.

  6. This is the first report to demonstrate that TNFalpha (显示 TNF ELISA试剂盒)-induced sickness behavior is fully mediated by TNF-R1 (显示 TNFRSF1A ELISA试剂盒) and that the adaptor protein FAN is a necessary intracellular intermediate for sickness behavior

  7. these results indicate the involvement of FAN in TNF (显示 TNF ELISA试剂盒)-induced gene expression and leukocyte recruitment, contributing to the establishment of the specific immune response.

Neutral Sphingomyelinase (N-SMase) Activation Associated Factor (NSMAF) 抗原简介

Antigen Summary

This gene encodes a WD-repeat protein that binds the cytoplasmic sphingomyelinase activation domain of the 55kD tumor necrosis factor receptor. This protein is required for TNF-mediated activation of neutral sphingomyelinase and may play a role in regulating TNF-induced cellular responses such as inflammation. Alternative splicing results in multiple transcript variants.

Gene names and symbols associated with NSMAF

  • protein FAN (EDI_035100) 抗体
  • neutral sphingomyelinase (N-SMase) activation associated factor (NSMAF) 抗体
  • neutral sphingomyelinase (N-SMase) activation associated factor (Nsmaf) 抗体
  • AA959567 抗体
  • C630007J05 抗体
  • Fan 抗体

Protein level used designations for NSMAF

protein FAN , factor associated with N-SMase activation , factor associated with neutral sphingomyelinase activation

GENE ID SPECIES
5884688 Entamoeba dispar SAW760
8439 Homo sapiens
18201 Mus musculus
353233 Rattus norvegicus
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