anti-Neurofilament, Heavy Polypeptide (NEFH) 抗体

Neurofilaments are type IV intermediate filament heteropolymers composed of light, medium, and heavy chains. 再加上,我们可以发Neurofilament, Heavy Polypeptide 试剂盒 (39)Neurofilament, Heavy Polypeptide 蛋白 (8)和数多这个蛋白质的别的产品。

列出全部抗体 基因 基因ID UniProt
NEFH 380684 P19246
NEFH 24587  
NEFH 4744 P12036

antibodies-online.cn销售最多的anti-Neurofilament, Heavy Polypeptide 抗体

Showing 10 out of 448 products:

产品编号 适用 宿主 标记 应用范围 图像 规格 供应商 交付 价格 详细
小鼠 非结合性 IHC (fro), IHC (p), WB 0.1 mg Log in to see 29至35个工作日
¥3,783.60
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小鼠 非结合性 ELISA (Capture), EIA, IHC (fro), WB 0.1 mg Log in to see 29至35个工作日
¥2,774.62
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小鸡 小鼠 非结合性 IHC (fro), IF, IHC (p), WB   0.1 mg Log in to see 29至35个工作日
¥3,783.60
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非结合性 IF (p), IHC (p) Formalin-fixed and paraffin embedded rat brain labeled with Anti-NF-H Polyclonal Antibody, Unconjugated  at 1:200 followed by conjugation to the secondary antibody and DAB staining Formalin-fixed and paraffin embedded rat brain labeled with Anti-NF-H Polyclonal Antibody, Unconjugated  at 1:200 followed by conjugation to the secondary antibody and DAB staining 100 μL Log in to see 14至17个工作日
¥2,709.56
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小鼠 非结合性 WB NEFH monoclonal antibody (M01), clone 2E8 Western Blot analysis of NEFH expression in HeLa. Detection limit for recombinant GST tagged NEFH is approximately 0.03 ng/mL as a capture antibody. 0.1 mg Log in to see 11至15个工作日
¥3,179.71
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所有种类 小鼠 非结合性 EIA, IHC (fro), IF, IHC (p), WB   0.2 mg Log in to see 29至35个工作日
¥4,288.05
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所有种类 小鼠 非结合性 IHC (fro), IF, IHC (p), WB   0.1 mg Log in to see 29至35个工作日
¥2,774.62
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REACT_Bird 小鼠 非结合性 IHC (p), IHC, ELISA, WB Rat spinal cord homogenate showing the major intermediate filament proteins of the nervous system (lane 1). The remaining lanes show blots of this material stainted with various antibodies including ABIN152482 (lane 2). 0.1 mL Log in to see 25至31个工作日
¥3,119.56
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小鼠 非结合性 IHC (fro), IHC (p), WB Anti-NF200 antibody (monoclonal), IHC(P) IHC(P): Rat Brain Tissue 100 μg Log in to see 26至32个工作日
¥2,560.58
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Cow 小鼠 非结合性 ICC, IF, IHC, IHC (p), in vitro, WB Immunocytochemistry/Immunofluorescence: NF-H Antibody (NF-01) [ABIN269048] - Analysis using the Alexa Fluor (R) 488 conjugate of ABIN269048. Ataining of NF-H in frozen monkey foot pad skin shows sensory fibers. Image from verified customer review. Immunohistochemistry: NF-H Antibody (NF-01) [ABIN269048] - Fig. 1. Immunohistochemistry staining of human cerebellum (paraffin-embedded sections) with anti-200kDa Neurofilament Heavy protein (NF-01). 0.1 mg Log in to see 25至31个工作日
¥3,119.56
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通过反应活性、应用领域、克隆类型和共轭标记 NEFH 抗体

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引用最多的anti-Neurofilament, Heavy Polypeptide 抗体

  1. Human Monoclonal NEFH Primary Antibody for ELISA (Capture), EIA - ABIN614809 : Côté, Collard, Julien: Progressive neuronopathy in transgenic mice expressing the human neurofilament heavy gene: a mouse model of amyotrophic lateral sclerosis. in Cell 1993 (PubMed)
    Show all 7 references for 614809

  2. Human Monoclonal NEFH Primary Antibody for WB - ABIN393231 : Shrestha, Irvin, Taylor, Wiener, Pajewski, Haritunians, Delaney, Schambelan, Polak, Arnett, Chen, Grunfeld: A genome-wide association study of carotid atherosclerosis in HIV-infected men. in AIDS 2010 (PubMed)
    Show all 5 references for 393231

  3. Chicken Monoclonal NEFH Primary Antibody for IHC (fro), IF - ABIN112360 : Bauwens, De Groot, Ramaekers, Veldman, Huizing: Expression of intermediate filament proteins in the adult human vestibular labyrinth. in The Annals of otology, rhinology, and laryngology 1992 (PubMed)
    Show all 2 references for 112360

  4. Bird (Avian) Monoclonal NEFH Primary Antibody for IHC (p), IHC - ABIN152482 : Harris, Ayyub, Shaw: A molecular dissection of the carboxyterminal tails of the major neurofilament subunits NF-M and NF-H. in Journal of neuroscience research 1992 (PubMed)
    Show all 2 references for 152482

  5. Human Monoclonal NEFH Primary Antibody for IHC (fro), IHC (p) - ABIN1108414 : Lees, Shneidman, Skuntz, Carden, Lazzarini: The structure and organization of the human heavy neurofilament subunit (NF-H) and the gene encoding it. in The EMBO journal 1988 (PubMed)
    Show all 2 references for 1108414

  6. Human Polyclonal NEFH Primary Antibody for IF (p), IHC (p) - ABIN2177936 : Liu, Nie, Zhao, Zhang, Zhang, Wang, Cheng: Conserved dopamine neurotrophic factor-transduced mesenchymal stem cells promote axon regeneration and functional recovery of injured sciatic nerve. in PLoS ONE 2014 (PubMed)
    Show all 2 references for 2177936

  7. Cow (Bovine) Monoclonal NEFH Primary Antibody for ICC, IF - ABIN269048 : van der Kallen, Eggers, Ehlert, Verhaagen, Smit, van Kesteren: Genetic Deletion of the Transcriptional Repressor NFIL3 Enhances Axon Growth In Vitro but Not Axonal Repair In Vivo. in PLoS ONE 2015 (PubMed)

  8. All Species Monoclonal NEFH Primary Antibody for EIA, IHC (fro) - ABIN111967 : Lukás, Dráber, Bucek, Dráberová, Viklický, Dolezel: Expression of phosphorylated high molecular weight neurofilament protein (NF-H) and vimentin in human developing dorsal root ganglia and spinal cord. in Histochemistry 1994 (PubMed)

更多抗Neurofilament, Heavy Polypeptide的相互作用对抗体

Mouse (Murine) Neurofilament, Heavy Polypeptide (NEFH) interaction partners

  1. Microgravity causes substantial down-regulation of nerve tissue proteins, choline acetyltransferase, NF200, and calbindin (显示 CALB1 抗体) in mouse motor neurons.

  2. Data conclude that NF-H and NF-M (显示 CEBPB 抗体) C-terminal domains do not normally regulate NF transport rates as previously proposed, but instead increase the proteolytic resistance of NF, thereby stabilizing the stationary neurofilament cytoskeleton along axons.

  3. plasma NfH levels closely reflect later stages of disease progression and therapeutic response in the SOD1 (显示 SOD1 抗体)(G93A) mouse model of amyotrophic lateral sclerosis

  4. NFH expression reveals an exquisite level of Cb stripe complexity that respects the transverse zone divisions and delineates an intricately patterned target field for Cb afferents.

  5. results obtained in mouse model for leprous neuropathy indicate biochemical alterations in neurofilaments, i.e., hyperphosphorylation of NF-H and NF-M (显示 CEBPB 抗体)

  6. Overexpression of peripherin (显示 PRPH 抗体) in mice deficient for neurofilament light (NF-L (显示 NEFL 抗体)) subunits induced a progressive ALS-like spinal motor neuron degeneration (显示 CLN8 抗体) prevented by simultaneous overexpression of NF-H

  7. NF-H regulates the association of NFs with kinesin. Phosphorylation of NF-H dissociates NFs from kinesin and provides a mechanism by which NF-H phosphorylation can contribute to the slowing of NF axonal transport.

  8. Alpha-internexin (显示 INA 抗体) coassembles with all 3 neurofilament proteins into a single network of filaments in quadruple-transfected cells. Deleting NF-M (显示 CEBPB 抗体) alone or together with NF-H in mice reduces alpha-internexin (显示 INA 抗体) transport & content in axons throughout the CNS.

  9. We have validated the serum pNF-H assay as an unbiased measurement of axonal injury in EAE, facilitating rapid screening of potential neuroprotective therapies in this model.

  10. RE1 silencing transcription factor (显示 REST 抗体) (REST) plays a contributory role in the neuron-specific expression of the alpha-internexin (显示 INA 抗体), NF-H and NF-M (显示 CEBPB 抗体) genes

Human Neurofilament, Heavy Polypeptide (NEFH) interaction partners

  1. data support the use of Cebrospinal fluid phosphorylated NFH as a prognostic biomarker for amyotrophic lateral sclerosis.

  2. Study found a significant correlation between values of 8-hydroxy-2'-deoxyguanosine and phosphorylated NF-H only in clinically isolated syndrome group. While the plasma values of 8-hydroxy-2'-deoxyguanosine reflect the degree of acute demyelination in clinically isolated syndrome, phosphorylated NF-H values reflect that in relapsing-remitting multiple sclerosis.

  3. Results provide evidence that in particular pNfH can be used as a good diagnostic biomarker of ALS (显示 IGFALS 抗体) at the diagnostic stage. Moreover, results indicate that NfL (显示 NEFL 抗体) may be useful in monitoring disease progression in a subset of patients.

  4. Level of neurofilament heavy chain and light chains were significantly elevated in the cerebrospinal fluid of Amyotrophic Lateral Sclerosis (ALS) patients compared to healthy controls/controls without parenchymal central nervous system involvement and ALS mimic disease patients.

  5. Study found a significant increase of pNF-H levels in both plasma and CSF (显示 CSF2 抗体) in amyotrophic lateral sclerosis patients

  6. Studied diagnostic Value of Serum Levels of GFAP (显示 GFAP 抗体), pNF-H, and NSE (显示 ENO2 抗体) Compared With Clinical Findings in Severity Assessment of Human Traumatic Spinal Cord Injury.

  7. This study demonstrated that Higher NF-L (显示 NEFL 抗体) concentrations (beta = -0.26) were associated with functional decline in patients with vascular burden.

  8. Phospho-NFH levels were significantly higher in amyotrophic lateral sclerosis patients in comparison with controls, in particular in fast progressors.

  9. Data identified NEFH methylation as a candidate epigenetic marker for prognosis of RCC patients as well as prediction of anti-vascular endothelial growth factor-based therapy response.

  10. Subconcussive repetitive trauma in amateur boxing causes a mild traumatic brain injury that may be diagnosed by CSF (显示 CSF2 抗体) analysis of expressed pNFH, even without unconsciousness or concussion symptoms.

Neurofilament, Heavy Polypeptide (NEFH) 抗原简介

蛋白简介

Neurofilaments are type IV intermediate filament heteropolymers composed of light, medium, and heavy chains. Neurofilaments comprise the axoskeleton and functionally maintain neuronal caliber. They may also play a role in intracellular transport to axons and dendrites. This gene encodes the heavy neurofilament protein. This protein is commonly used as a biomarker of neuronal damage and susceptibility to amyotrophic lateral sclerosis (ALS) has been associated with mutations in this gene.

Gene names and symbols associated with NEFH

  • neurofilament heavy polypeptide (MCYG_06231) 抗体
  • neurofilament, heavy polypeptide (Nefh) 抗体
  • neurofilament, heavy polypeptide (NEFH) 抗体
  • mKIAA0845 抗体
  • NEFH 抗体
  • NF-H 抗体
  • NF200 抗体
  • NFH 抗体

Protein level used designations for NEFH

neurofilament heavy polypeptide , 200 kDa neurofilament protein , neurofilament 200kDa , neurofilament triplet H protein , NF-H , neurofilament, heavy polypeptide 200kDa , neurofilament, heavy polypeptide , neurofilament, heavy polypeptide 200kDa-like , heavy neurofilament protein , intermediate filament protein

GENE ID SPECIES
9222506 Arthroderma otae CBS 113480
380684 Mus musculus
24587 Rattus norvegicus
4744 Homo sapiens
100156492 Sus scrofa
528842 Bos taurus
442940 Canis lupus familiaris
417020 Gallus gallus
100716406 Cavia porcellus
101107472 Ovis aries
101087272 Felis catus
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