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NPC1L1 蛋白

(NPC1 (Niemann-Pick Disease, Type C1, Gene)-Like 1 (NPC1L1))
The protein encoded by this gene is a multi-pass membrane protein. It contains a conserved N-terminal Niemann-Pick C1 (NPC1) domain and a putative sterol-sensing domain (SSD) which includes a YQRL motif functioning as a plasma membrane to trans-Golgi network transport signal in other proteins. This protein takes up free cholesterol into cells through vesicular endocytosis and plays a critical role in the absorption of intestinal cholesterol. It also has the ability to transport alpha-tocopherol (vitamin E). The drug ezetimibe targets this protein and inhibits the absorption of intestinal cholesterol and alpha-tocopherol. In addition, this protein may play a critical role in regulating lipid metabolism. Polymorphic variations in this gene are associated with plasma total cholesterol and low-density lipoprotein cholesterol (LDL-C) levels and coronary heart disease (CHD) risk. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2009].
NPC1L1 Protein (AA 1258-1359) (His tag) NPC1L1 Protein (AA 1258-1359) (His tag) NPC1L1 Protein (AA 1258-1359) (His tag) (ABIN3084683)

Crystallography grade NPC1L1 宿主: 人 宿主: 大肠杆菌(E. Coli) Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. Crys, ELISA, SDS, WB

NPC1L1 Protein (AA 904-1139) (His tag) NPC1L1 Protein (AA 904-1139) (His tag) NPC1L1 Protein (AA 904-1139) (His tag) (ABIN3084682)

Crystallography grade NPC1L1 宿主: 人 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. Crys, ELISA, SDS, WB

NPC1L1 Protein (AA 373-632) (His tag) NPC1L1 Protein (AA 373-632) (His tag) NPC1L1 Protein (AA 373-632) (His tag) (ABIN3084681)

Crystallography grade NPC1L1 宿主: 人 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. Crys, ELISA, SDS, WB

NPC1L1 蛋白 by Grade

Find NPC1L1 蛋白 with a specific Grade. The Grade listed below are among those available. Click on a link to go to the corresponding products.

NPC1L1 蛋白 by Origin

Find NPC1L1 蛋白 for a variety of species such as anti-Human NPC1L1, anti-Mouse NPC1L1. The species listed below are among those available. Click on a link to go to the corresponding products.

NPC1L1 蛋白 by Source

Here you will find NPC1L1 蛋白 proteins organized by several key sources. By clicking on a link, you can access the products. For additional sources, please use our search function.

NPC1L1 蛋白 by 蛋白类型

Here you can find NPC1L1 蛋白 proteins categorized by available protein types. Additional protein types can be located using our search function.

NPC1L1 蛋白 by 应用范围

Find NPC1L1 蛋白 validated for a specific application such as ELISA, SDS, WB, Crys. Some of the available applications are listed below. Click on a link to go to the corresponding products.

Popular NPC1L1 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN3084683
Quantity 1 mg
Datasheet Datasheet
Reactivity Human
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3084682
Quantity 1 mg
Datasheet Datasheet
Reactivity Human
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3084681
Quantity 1 mg
Datasheet Datasheet
Reactivity Human
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3084680
Quantity 1 mg
Datasheet Datasheet
Reactivity Mouse
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3123831
Quantity 1 mg
Datasheet Datasheet
Reactivity Mouse
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3123830
Quantity 1 mg
Datasheet Datasheet
Reactivity Mouse
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3123829
Quantity 1 mg
Datasheet Datasheet
Reactivity Human
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3118912
Quantity 1 mg
Datasheet Datasheet
Reactivity Mouse
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3135841
Quantity 1 mg
Datasheet Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
Cat. No. ABIN7490787
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
Cat. No. ABIN7491703
Quantity 100 μg
Datasheet Datasheet

Aliases for NPC1L1 蛋白

NPC1 like intracellular cholesterol transporter 1 (NPC1L1) 蛋白
NPC1 like 1 (npc1l1) 蛋白
NPC1-like 1 (npc1l1) 蛋白
NPC1 like intracellular cholesterol transporter 1 (Npc1l1) 蛋白
9130221N23Rik 蛋白
Gm243 蛋白
NPC1L1 蛋白
NPC11L1 蛋白
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