NIMA (Never in Mitosis Gene A)- Related Kinase 9 (NEK9) ELISA试剂盒

Pleiotropic regulator of mitotic progression, participating in the control of spindle dynamics and chromosome separation. 再加上,我们可以发NIMA (Never in Mitosis Gene A)- Related Kinase 9 抗体 (131)NIMA (Never in Mitosis Gene A)- Related Kinase 9 蛋白 (8)和数多这个蛋白质的别的产品。

list all ELISA KIts 基因 基因ID UniProt
NEK9 217718 Q8K1R7
NEK9 91754 Q8TD19
NEK9 299204  

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Zebrafish NIMA (Never in Mitosis Gene A)- Related Kinase 9 (NEK9) interaction partners

  1. requirement for Nek8 (显示 NEK8 ELISA试剂盒) in left-right patterning is conserved

  2. Nek8 (显示 NEK8 ELISA试剂盒) acts downstream of Inv (显示 INVS ELISA试剂盒) function

  3. cross-species analysis between zebrafish and mouse demonstrates taht NEK8 (显示 NEK8 ELISA试剂盒) has a role in development of pronephric cysts

Xenopus laevis NIMA (Never in Mitosis Gene A)- Related Kinase 9 (NEK9) interaction partners

  1. Nercc1 contributes to both the centrosomal and the chromatin/Ran pathways that collaborate in the organization of a bipolar spindle

Mouse (Murine) NIMA (Never in Mitosis Gene A)- Related Kinase 9 (NEK9) interaction partners

  1. NEK9 is a critical component of the replication stress response that promotes CHK1 (显示 CHEK1 ELISA试剂盒) activity, maintaining genome integrity following challenges to DNA replication.

  2. Knockdown of Nek9 also impaired the spindle-pole localization of gamma-tubulin (显示 TUBG1 ELISA试剂盒) and resulted in retention of the spindle assembly checkpoint protein Bub3 (显示 BUB3 ELISA试剂盒) at the kinetochores.

Human NIMA (Never in Mitosis Gene A)- Related Kinase 9 (NEK9) interaction partners

  1. Signaling cascade of the NIMA-related kinases (Neks) Nek6 (显示 NEK6 ELISA试剂盒), Nek7 (显示 NEK7 ELISA试剂盒), and Nek9 is required for the localization and function of two kinesins essential for cytokinesis, Mklp2 (显示 KIF20A ELISA试剂盒) and Kif14 (显示 KIF14 ELISA试剂盒) to properly coordinate cytokinesis.

  2. Recessive NEK9 mutation is associated with lethal skeletal dysplasia.

  3. Somatic Mutations in NEK9 Cause Nevus Comedonicus.

  4. Overall, these results highlight the complexity of virus-host interactions and identify a new role for the cellular protein Nek9 during human adenovirus infection, suggesting a role for Nek9 in regulating p53 (显示 TP53 ELISA试剂盒) target gene expression.

  5. The C-terminal domain of Nek9 activates Nek7 (显示 NEK7 ELISA试剂盒) through promoting back-to-back dimerization.

  6. The findings demonstrate that a novel NEK9 network regulates the growth of cancer cells lacking functional p53 (显示 TP53 ELISA试剂盒).

  7. NEK9 inhibition represents a novel anti-cancer strategy by induction of mitotic catastrophe via impairment of spindle dynamics, cytokinesis and mitotic checkpoint (显示 BUB3 ELISA试剂盒) control.

  8. Structural analysis of LC8 (显示 DYNLL1 ELISA试剂盒) with both Nek9 peptides, together with different biophysical experiments, explains the observed diminished binding affinity of Nek9 to LC8 (显示 DYNLL1 ELISA试剂盒) upon phosphorylation on Ser (显示 SIGLEC1 ELISA试剂盒)(944) within the Nek9 sequence

  9. Nek9 phosphorylates NEDD1 (显示 NEDD1 ELISA试剂盒) on Ser377 driving its recruitment and thereby that of gamma-tubulin (显示 TUBG1 ELISA试剂盒) to the centrosome in mitotic cells.

  10. The interaction between the human NimA-like protein kinase (显示 CDK7 ELISA试剂盒) Nek9 and the Helicobacter HcpC has been validated by ELISA and surface plasmon resonance.

NIMA (Never in Mitosis Gene A)- Related Kinase 9 (NEK9) 抗原简介

Antigen Summary

Pleiotropic regulator of mitotic progression, participating in the control of spindle dynamics and chromosome separation. Phosphorylates different histones, myelin basic protein, beta-casein, and BICD2. Phosphorylates histone H3 on serine and threonine residues and beta-casein on serine residues Important for G1/S transition and S phase progression. Phosphorylates NEK6 and NEK7 and stimulates their activity by releasing the autoinhibitory functions of Tyr-108 and Tyr-97 respectively (By similarity).

Gene names and symbols associated with NEK9

  • NIMA (never in mitosis gene a)- related kinase 9 (NEK9) 抗体
  • NIMA (never in mitosis gene a)-related kinase 8 (nek8) 抗体
  • NIMA (never in mitosis gene a)- related kinase 8 (nek8) 抗体
  • NIMA (never in mitosis gene a)- related kinase 8 (NEK8) 抗体
  • NIMA-related kinase 9 (nek9) 抗体
  • NIMA-related kinase 8 (LOC100345106) 抗体
  • NIMA (never in mitosis gene a)- related kinase 9 (nek9) 抗体
  • NIMA (never in mitosis gene a)-related expressed kinase 9 (Nek9) 抗体
  • NIMA-related kinase 9 (NEK9) 抗体
  • NIMA-related kinase 9 (Nek9) 抗体
  • C130021H08Rik 抗体
  • jck 抗体
  • MGC80499 抗体
  • MGC88903 抗体
  • Nek8 抗体
  • NEK9 抗体
  • nek12a 抗体
  • NERCC 抗体
  • NERCC1 抗体
  • nphp9 抗体

Protein level used designations for NEK9

serine/threonine-protein kinase Nek9 , NIMA-related kinase 8 , never in mitosis A-related kinase 8 , nimA-related protein kinase 8 , serine/threonine-protein kinase Nek8 , NIMA (never in mitosis gene a)- related kinase 8 , NIMA (never in mitosis gene a)- related kinase 9 , NIMA (never in mitosis gene a)-related expressed kinase 8 , serine/threonine-protein kinase Nek9-like , nercc1 kinase , never in mitosis A-related kinase 9 , nimA-related protein kinase 9 , NIMA-related kinase Nek8 , nimA-related kinase 8 , NIMA-family kinase Nercc1 , XNek9

GENE ID SPECIES
428891 Gallus gallus
534652 Bos taurus
100152772 Sus scrofa
171094 Danio rerio
448753 Xenopus (Silurana) tropicalis
455033 Pan troglodytes
701707 Macaca mulatta
779142 Xenopus laevis
100216232 Xenopus (Silurana) tropicalis
100345106 Oryctolagus cuniculus
100461917 Pongo abelii
100474361 Ailuropoda melanoleuca
100543466 Meleagris gallopavo
100556817 Anolis carolinensis
490790 Canis lupus familiaris
217718 Mus musculus
91754 Homo sapiens
299204 Rattus norvegicus
398600 Xenopus laevis
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