NFU1 Iron-Sulfur Cluster Scaffold Homolog (S. Cerevisiae) (NFU1) ELISA试剂盒

NFU1 encodes a protein that is localized to mitochondria and plays a critical role in iron-sulfur cluster biogenesis. 再加上,我们可以发NFU1 Iron-Sulfur Cluster Scaffold Homolog (S. Cerevisiae) 抗体 (5)NFU1 Iron-Sulfur Cluster Scaffold Homolog (S. Cerevisiae) 蛋白 (4)和数多这个蛋白质的别的产品。

list all ELISA KIts 基因 基因ID UniProt
 NFU1 NFU1 27247 Q9UMS0
小鼠 NFU1 NFU1 56748 Q9QZ23

适于 NFU1 Iron-Sulfur Cluster Scaffold Homolog (S. Cerevisiae) 相互作用对的更多 ELISA 试剂盒

Human NFU1 Iron-Sulfur Cluster Scaffold Homolog (S. Cerevisiae) (NFU1) interaction partners

  1. a direct role for human Nfu in the process of [2Fe-2S] cluster trafficking and delivery

  2. Analysis of protein stability and oligomeric state demonstrates that the Gly208Cys mutant increases the propensity to dimerize and perturbs the secondary structure composition. These changes appear to underlie the severely decreased ability of mutant NFU1 to accept an Fe/S cluster from physiologically relevant sources.

  3. Study used NMR spectroscopy and small-angle X-ray scattering data to determine the 3D structure of human mitochondrial NFU1 in its apo (显示 C9orf3 ELISA试剂盒)- and iron-sulfur cluster-containing holo-form. Apo (显示 C9orf3 ELISA试剂盒)- NFU1 is monomeric, whereas holo-NFU1 consists of a trimer of three [4Fe-4S] cluster-linked dimers.

  4. a leaky splicing regulation due to a splice site mutation (c.545+5G>A) that produces small amounts of wild type NFU1 mRNA that might result in enough protein to partially lipoylate and restore the activity of lipoic acid-dependent enzymes and the assembly and activity of complex I.

  5. A new NFU1 mutation is reported in a patient presenting with a milder phenotype characterized by a later onset, a slowly progressive spastic paraparesis with relapsing-remitting episodes, mild cognitive impairment and a long survival.

  6. This study provides new insights into the molecular bases of NFU1 disease.

  7. A fatal mitochondrial disease is associated with defective NFU1 function in the maturation of a subset of mitochondrial Fe-S proteins

  8. Mutations in iron-sulfur cluster scaffold genes NFU1 and BOLA3 (显示 BOLA3 ELISA试剂盒) cause a fatal deficiency of multiple respiratory chain and 2-oxoacid dehydrogenase enzymes [case report]

  9. Analyses of genomic DNA, transcripts, and translation products indicate that alternative splicing of a common pre-mRNA results in synthesis of two Nfu isoforms with distinct subcellular localizations.

  10. Laforin (显示 EPM2A ELISA试剂盒) interacts with HIRIP5.

NFU1 Iron-Sulfur Cluster Scaffold Homolog (S. Cerevisiae) (NFU1) 抗原简介

Antigen Summary

This gene encodes a protein that is localized to mitochondria and plays a critical role in iron-sulfur cluster biogenesis. The encoded protein assembles and transfers 4Fe-4S clusters to target apoproteins including succinate dehydrogenase and lipoic acid synthase. Mutations in this gene are a cause of multiple mitochondrial dysfunctions syndrome-1, and pseudogenes of this gene are located on the short arms of chromosomes 1 and 3. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Gene names and symbols associated with NFU1

  • NFU1 iron-sulfur cluster scaffold homolog (S. cerevisiae) (NFU1) 抗体
  • NFU1 iron-sulfur cluster scaffold homolog (S. cerevisiae) (Nfu1) 抗体
  • 0610006G17Rik 抗体
  • CGI-33 抗体
  • HIRIP 抗体
  • Hirip5 抗体
  • MMDS1 抗体
  • Nfu 抗体
  • NifU 抗体
  • NIFUC 抗体

Protein level used designations for NFU1

HIRA-interacting protein 5 , NFU1 iron-sulfur cluster scaffold homolog, mitochondrial , NifU-like C-terminal domain containing , iron-sulfur cluster scaffold protein , histone cell cycle regulation defective interacting protein 5 , mHIRIP5

GENE ID SPECIES
27247 Homo sapiens
56748 Mus musculus
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