anti-NADH Dehydrogenase (Ubiquinone) Flavoprotein 1, 51kDa (NDUFV1) 抗体

The mitochondrial respiratory chain provides energy to cells via oxidative phosphorylation and consists of four membrane-bound electron-transporting protein complexes (I-IV) and an ATP synthase (complex V). 再加上,我们可以发NDUFV1 蛋白 (9)和数多这个蛋白质的别的产品。

列出全部抗体 基因 基因ID UniProt
NDUFV1 17995 Q91YT0
NDUFV1 293655  
NDUFV1 4723 P49821
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antibodies-online.cn销售最多的anti-NDUFV1 抗体

Showing 10 out of 74 products:

产品编号 适用 宿主 标记 应用范围 图像 规格 供应商 交付 价格 详细
Cow 非结合性 WB <b>WB Suggested Anti-NDUFV1 Antibody Titration: </b>2.5ug/ml<br><b>Positive Control: </b>HepG2 cell lysate 100 μL Log in to see 2至3个工作日
$229.00
详细
非结合性 WB NDUFV1 Antibody (N-term) (ABIN1881573) western blot analysis in MDA-MB453 cell line lysates (35 µg/lane). This demonstrates the NDUFV1 antibody detected the NDUFV1 protein (arrow). 400 μL Log in to see 10至11个工作日
$324.50
详细
Bat 非结合性 WB 100 μg Log in to see 7至9个工作日
$493.17
详细
小鼠 非结合性 RNAi, ELISA, WB NDUFV1 monoclonal antibody (M01), clone 4A7 Western Blot analysis of NDUFV1 expression in A-431 Western blot analysis of NDUFV1 over-expressed 293 cell line, cotransfected with NDUFV1 Validated Chimera RNAi (Lane 2) or non-transfected control (Lane 1). Blot probed with NDUFV1 monoclonal antibody (M01), clone 4A7. GAPDH ( 36.1 kDa ) used as specificity and loading control. 100 μg Log in to see 11至12个工作日
$430.00
详细
非结合性 IHC (p), IHC, WB Immunohistochemistry-Paraffin: NDUFV1 Antibody [NBP1-33074] - Paraffin-embedded U37C xenograft, using antibody at 1:500 dilution. Western Blot: NDUFV1 Antibody [NBP1-33074] - Sample (50 ug of whole cell lysate) A: Mouse brain 10% SDS PAGE; antibody diluted at 1:1000. 100 μL Log in to see 7至9个工作日
$447.56
详细
非结合性 IF (p), IHC (p), WB Antigen: 0.2 µg/100 µL  Primary: Antiserum, 1:500, 1:1000, 1:2000, 1:4000, 1:8000, 1:16000, 1:32000;  Secondary: HRP conjugated Goat-Anti-Rabbit IgG at 1: 5000; TMB staining; Read the data in MicroplateReader by 450 Formalin-fixed and paraffin embedded rat brain labeled with Anti-NDUFV1 Polyclonal Antibody, Unconjugated (ABIN751738) at 1:200 followed by conjugation to the secondary antibody and DAB staining 100 μL Log in to see 3至7个工作日
$295.90
详细
非结合性 IHC (p), WB IHC-P Image Immunohistochemical analysis of paraffin-embedded U373 xenograft, using NDUFV1, antibody at 1:500 dilution. WB Image Sample (30 ug of whole cell lysate) A: Hep G2 , 10% SDS PAGE antibody diluted at 1:1000 100 μL Log in to see 1至2个工作日
$358.60
详细
非结合性 ELISA, WB 100 μg Log in to see 2至3个工作日
$343.75
详细
非结合性 IC, IF, WB Immunofluorescent analysis of NDUFV1 staining in A549 cells. Formalin-fixed cells were permeabilized with 0.1% Triton X-100 in TBS for 5-10 minutes and blocked with 3% BSA-PBS for 30 minutes at room temperature. Cells were probed with the primary antibody Western blot analysis of NDUFV1 expression in mouse kidney (A), rat brain (B) whole cell lysates. 200 μL Log in to see 13至14个工作日
$487.50
详细
Alexa Fluor 594 IF (p)   100 μL Log in to see 14至21个工作日
$405.90
详细

通过反应活性、应用领域、克隆类型和共轭标记 NDUFV1 抗体

特性 应用范围 宿主 克隆类型 标记
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引用最多的anti-NDUFV1 抗体

  1. Human Polyclonal NDUFV1 Primary Antibody for WB - ABIN1881573 : Morán, Rivera, Sánchez-Aragó, Blázquez, Merinero, Ugalde, Arenas, Cuezva, Martín: Mitochondrial bioenergetics and dynamics interplay in complex I-deficient fibroblasts. in Biochimica et biophysica acta 2010 (PubMed)
    Show all 3 Pubmed References

  2. Human Monoclonal NDUFV1 Primary Antibody for RNAi, ELISA - ABIN518257 : Sheftel, Stehling, Pierik, Netz, Kerscher, Elsässer, Wittig, Balk, Brandt, Lill: Human ind1, an iron-sulfur cluster assembly factor for respiratory complex I. in Molecular and cellular biology 2009 (PubMed)

更多抗NDUFV1的相互作用对抗体

Mouse (Murine) NADH Dehydrogenase (Ubiquinone) Flavoprotein 1, 51kDa (NDUFV1) interaction partners

  1. NDUFV1 knockdown-induced blockage of insulin (显示 INS 抗体) signaling was released by protein-tyrosine phosphatase 1B (显示 PTPN1 抗体) knockdown in C2C12 myotubes, and NDUFV1 or SIRT1 (显示 SIRT1 抗体) knockdown did not affect mitochondria biogenesis during C2C12 myogenesis. myogenesis.

  2. The authors use green fluorescent-tagged complex I subunits to determine the kinetics of assembly. Tagged human NDUFV1 can replace endogenous protein in the holo-complex I protein and was also found in complex I subassemblies, suggesting that NDUFV1 may directly incorporate into the holo-enzyme and may also assemble into smaller complexes or in a monomer pool.

  3. The authors clone and characterize the human NADH dehydrogenase (显示 NDUFA2 抗体) [ubiquinone] flavoprotein 1, mitochondrial protein (显示 COX6B2 抗体), also known as NDUFV1. They identify transcription factor binding sites as well as consensus motifs for NADH, flavin mononucleotide, and iron-sulfur binding sites. The human ortholog has high homology to the cow NDUFV1 protein.

  4. The authors provide an overview of the function and assembly of human complex I, also known as NADH dehydrogenase (显示 NDUFA2 抗体) (ubiquinone) 1 alpha subcomplex. They discuss its role in oxidative phosphorylation and the implications of complex I deficiency in disease.

Human NADH Dehydrogenase (Ubiquinone) Flavoprotein 1, 51kDa (NDUFV1) interaction partners

  1. we have used a yeast model system to study the molecular consequences of 16 single amino acid substitutions, classified as pathogenic, in the NDUFV1 subunit of complex I

  2. The presented clinical courses of NDUFV1 and NDUFS1 (显示 NDUFS1 抗体) mutation-based complex I deficiencies are characterized by leukoencephalopathy or early death and expand the already heterogeneous phenotypic spectrum.

  3. small number of putative de novo variants were transmitted from BAP (显示 PHB2 抗体) parents to their ASD (显示 ARSD 抗体) offspring, and evidence emerged for a rare duplication CNV at 11p13.3 harboring two putative developmental/neuropsychiatric susceptibility gene(s), GSTP1 (显示 GSTP1 抗体) and NDUFV1.

  4. The results affirm that NDUFV1 mutations are causative of the phenotype in two siblings affected by a diffuse leukodystrophy.

  5. observed 2 consanguinous siblings with early-onset encephalopathy, medulla, brainstem and mesencephalon lesions and death before 8 months of age, caused by a complex I deficiency; identified a missense mutation in the NDUFV1 gene; the mutation, p.Arg386His, affects a highly conserved residue

  6. study describes clinical, radiological, biochemical and molecular data of 6 patients with Leigh syndrome with novel mutations in NDUFV1 and NDUFS2 (显示 NDUFS2 抗体); 2 siblings were homozygous for previously undescribed R386C mutation in NDUFV1

  7. significant negative-correlation between left ventricular end-diastolic dimension and NDUFV1 production in dilated cardiomyopathy

  8. Sp1 (显示 PSG1 抗体) was abnormally expressed in schizophrenia and its mRNA alteration pattern paralleled that of NDUFV1 and NDUFV2 (显示 NDUFV2 抗体) in schizophrenic patients.

  9. Mutations in the NDUFV1 gene is linked to a delayed mitochondrial network recovery in OXPHOS disorders.

NDUFV1 抗原简介

蛋白简介

The mitochondrial respiratory chain provides energy to cells via oxidative phosphorylation and consists of four membrane-bound electron-transporting protein complexes (I-IV) and an ATP synthase (complex V). This gene encodes a 51 kDa subunit of the NADH:ubiquinone oxidoreductase complex I\; a large complex with at least 45 nuclear and mitochondrial encoded subunits that liberates electrons from NADH and channels them to ubiquinone. This subunit carries the NADH-binding site as well as flavin mononucleotide (FMN)- and Fe-S-biding sites. Defects in complex I are a common cause of mitochondrial dysfunction\; a syndrome that occurs in approximately 1 in 10,000 live births. Mitochondrial complex I deficiency is linked to myopathies, encephalomyopathies, and neurodegenerative disorders such as Parkinson's disease and Leigh syndrome. Alternative splicing results in multiple transcript variants encoding distinct isoforms.

Gene names and symbols associated with NDUFV1

  • NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial (LOC408367) 抗体
  • NADH:ubiquinone oxidoreductase core subunit V1 (NDUFV1) 抗体
  • NADH:ubiquinone oxidoreductase core subunit V1 (ndufv1) 抗体
  • NADH dehydrogenase ubiquinone flavoprotein 1 (ndufv1) 抗体
  • NADH dehydrogenase (ubiquinone) flavoprotein 1, 51kDa (Ndufv1) 抗体
  • NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial (LOC100179486) 抗体
  • NADH dehydrogenase (ubiquinone) flavoprotein 1 (ndufv1) 抗体
  • NADH dehydrogenase (ubiquinone) flavoprotein 1 (Ndufv1) 抗体
  • NADH:ubiquinone oxidoreductase core subunit V1 (Ndufv1) 抗体
  • NADH:ubiquinone oxidoreductase core subunit V1 L homeolog (ndufv1.L) 抗体
  • CI-51K 抗体
  • CI-51kD 抗体
  • CI51KD 抗体
  • DDBDRAFT_0188174 抗体
  • DDBDRAFT_0191420 抗体
  • DDB_0188174 抗体
  • DDB_0191420 抗体
  • GB17095 抗体
  • UQOR1 抗体
  • wu:fc01f01 抗体
  • wu:fc12f12 抗体
  • zgc:86620 抗体

Protein level used designations for NDUFV1

NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial , NADH dehydrogenase ubiquinone flavoprotein 1 , NADH-ubiquinone oxidoreductase , ubiquinone oxidoreductase , OXPHOS complex I 51 kDa subunit , NADH dehydrogenase (ubiquinone) flavoprotein 1, 51kDa , NADH dehydrogenase flavoprotein 1; 24 kDa (FP) , NADH-ubiquinone oxidoreductase 51 kDa subunit , complex I-51kD , complex I 51 kda subunit , complex I 51kDa subunit , complex I, mitochondrial respiratory chain , mitochondrial NADH dehydrogenase ubiquinone flavoprotein 1 , mitochondrial NADH:ubiquinone oxidoreductase 51 kda subunit , CI-51kD , NADH dehydrogenase flavoprotein 1 , NADH-ubiquinone oxidoreductase 51 kDa subunit, mitochondrial , mitochondrial complex I subunit NDUFV1

GENE ID SPECIES
408367 Apis mellifera
430210 Gallus gallus
496988 Xenopus (Silurana) tropicalis
8626872 Dictyostelium discoideum AX4
100122492 Nasonia vitripennis
100179486 Ciona intestinalis
445291 Danio rerio
17995 Mus musculus
293655 Rattus norvegicus
379907 Xenopus laevis
4723 Homo sapiens
476004 Canis lupus familiaris
287014 Bos taurus
747209 Pan troglodytes
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