anti-Myristoylated Alanine-Rich Protein Kinase C Substrate (MARCKS) 抗体

The protein encoded by MARCKS is a substrate for protein kinase C. 再加上,我们可以发MARCKS 试剂盒 (22)MARCKS 蛋白 (7)和数多这个蛋白质的别的产品。

列出全部抗体 基因 基因ID UniProt
MARCKS 17118 P26645
MARCKS 25603  
MARCKS 4082 P29966
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antibodies-online.cn销售最多的anti-MARCKS 抗体

Showing 10 out of 248 products:

产品编号 适用 宿主 标记 应用范围 图像 规格 供应商 交付 价格 详细
Cow 非结合性 IHC, WB WB Suggested Anti-MARCKS AntibodyTitration: 1.0 µg/mL <br /> Positive Control: Fetal Liver 100 μL Log in to see 2至3个工作日
$289.00
详细
Cow 非结合性 WB <b>Sample:</b> SH-SY5Y cells 2.0x10<sup>5</sup> cells<b><br></b><b>Primary dilution:</b> 1:2500<br><b>Secondary Antibody</b>: HRP-conjugated goat anti-rabbit IgG<br><b>Secondary dilution:</b> 1:5000<br><b>Image Submitted by</b>:Atsuhiro Tanabe<br>Pharma Sci Kitasato University 100 μL Log in to see 2至3个工作日
$289.00
详细
非结合性 ELISA, WB Western blot analysis of extracts from K562 cells treated with EGF 200ng/ml 30', using MARCKS (Phospho-Ser158) Antibody. The lane on the right is treated with the synthesized peptide. 100 μg Log in to see 2至3个工作日
$302.50
详细
非结合性 IF, ELISA, WB Western blot analysis of extracts from Jurkat cells, using MARCKS (Ab-158) Antibody. The lane on the right is treated with the synthesized peptide. Immunofluorescence analysis of A549 cells, using MARCKS (Ab-158) Antibody. The picture on the right is treated with the synthesized peptide. 100 μg Log in to see 2至3个工作日
$302.50
详细
非结合性 EIA, WB 0.4 mL Log in to see 6至8个工作日
$390.50
详细
非结合性 WB Western blot analysis of hMARCKS-K254 (ABIN389097) in Hela cell line lysates (35 µg/lane). MARCKS (arrow) was detected using the purified polyclonal antibody. 400 μL Log in to see 10至11个工作日
$324.50
详细
非结合性 IHC, ELISA Immunohistochemistry analysis of paraffin-embedded human brain, using MARCKS (Phospho-Ser163) Antibody. The picture on the right is treated with the synthesized peptide. 100 μg Log in to see 2至3个工作日
$302.50
详细
非结合性 IHC, ELISA, WB Western blot analysis of extracts from HepG2 cells, treated with LPS 100ng/ml 30', using MARCKS (Ab-163) Antibody. The lane on the right is treated with the synthesized peptide. Immunohistochemistry analysis of paraffin-embedded human brain tissue, using MARCKS (Ab-163) Antibody. The picture on the right is treated with the synthesized peptide. 100 μg Log in to see 2至3个工作日
$302.50
详细
小鼠 非结合性 WB MARCKS monoclonal antibody (M04), clone 2H4. Western Blot analysis of MARCKS expression in Raw 264.7. Detection limit for recombinant GST tagged MARCKS is approximately 0.1 ng/mL as a capture antibody. 0.1 mg Log in to see 8至11个工作日
$450.00
详细
小鼠 非结合性 IF, WB Immunofluorescence of monoclonal antibody to MARCKS on HeLa cell (antibody concentration 10 µg/mL). MARCKS monoclonal antibody (M06), clone 2C2. Western Blot analysis of MARCKS expression in Raw 264.7. (OMIN,80 kDa,http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=177061 50 μg Log in to see 8至11个工作日
$450.00
详细

通过反应活性、应用领域、克隆类型和共轭标记 MARCKS 抗体

特性 应用范围 宿主 克隆类型 标记
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引用最多的anti-MARCKS 抗体

  1. Chinese Hamster Polyclonal MARCKS Primary Antibody for WB - ABIN152966 : Zhang, Ahmed, McFarlane, Capone, Boreham, Truant, Igdoura, Trigatti: Regulation of SR-BI-mediated selective lipid uptake in Chinese hamster ovary-derived cells by protein kinase signaling pathways. in Journal of lipid research 2007 (PubMed)
    Show all 2 Pubmed References

  2. Human Polyclonal MARCKS Primary Antibody for IF, WB - ABIN362996 : Litherland, Elias, Hui, Macdonald, Catterall, Barter, Farren, Jefferson, Rowan: Protein kinase C isoforms zeta and iota mediate collagenase expression and cartilage destruction via STAT3- and ERK-dependent c-fos induction. in The Journal of biological chemistry 2010 (PubMed)
    Show all 5 Pubmed References

  3. Human MARCKS Primary Antibody for IHC - ABIN966535 : Pariser, Herradon, Ezquerra, Perez-Pinera, Deuel: Pleiotrophin regulates serine phosphorylation and the cellular distribution of beta-adducin through activation of protein kinase C. in Proceedings of the National Academy of Sciences of the United States of America 2005 (PubMed)

更多抗MARCKS的相互作用对抗体

Xenopus laevis Myristoylated Alanine-Rich Protein Kinase C Substrate (MARCKS) interaction partners

  1. The results indicated MARCKS may be the missing link in the regulation of the function (i.e., sodium transport) of epithelial sodium channels by anionic phospholipids.

Mouse (Murine) Myristoylated Alanine-Rich Protein Kinase C Substrate (MARCKS) interaction partners

  1. ENaC (显示 SCNN1A 抗体) activity is regulated by calpain-2 (显示 CAPN2 抗体) proteolysis of MARCKS.

  2. In the absence of Pin1 (显示 PIN1 抗体), MARCKS is hyper-phosphorylated, leading to loss of cell adhesions, and collapse of the growth cone.

  3. Findings suggest that MIR429 modulates mucin (显示 SLC13A2 抗体) secretion in human colorectal cells and mouse colitis tissues by up-regulating of MARCKS expression.

  4. Conditional deletion of MARCKS in ECs induces intracellular accumulation of mucins, elevated oxidative stress, and lipid droplet buildup.

  5. MARCKS acts as a "molecular switch," binding to and regulating PIP2 signaling to regulate processes like proplatelet extension (microtubule-driven) vs proplatelet branching (Arp2/3 and actin polymerization-driven).

  6. MARCKS knockdown arrested VSMC cell cycle by decreasing KIS (显示 UHMK1 抗体) expression. Decreased KIS (显示 UHMK1 抗体) expression resulted in nuclear trapping of p27kip1 (显示 CDKN1B 抗体) in VSMCs.

  7. MARCKS regulates the expression of proinflammatory cytokines in macrophages through activation of p38 (显示 CRK 抗体)/JNK (显示 MAPK8 抗体) MAPK (显示 MAPK1 抗体) and NF-kappaB (显示 NFKB1 抗体).

  8. Targeting phospho-MARCKS overcomes drug-resistance and induces antitumor activity in preclinical models of multiple myeloma.

  9. Grin 1 (显示 GPRIN1 抗体) is identified as a novel Cdk5 (显示 CDK5 抗体) substrate and MARCKS is confirmed as a Cdk5 (显示 CDK5 抗体) substrate.

  10. MARCKS appears to be a nonessential regulatory protein in mast cell exocytosis but exerts a negative modulation.

Zebrafish Myristoylated Alanine-Rich Protein Kinase C Substrate (MARCKS) interaction partners

  1. Marcksb is required for proper gastrulation movements of zebrafish.

Human Myristoylated Alanine-Rich Protein Kinase C Substrate (MARCKS) interaction partners

  1. data suggest a major contribution of MARCKS to kidney cancer growth and provide an alternative therapeutic strategy of improving the efficacy of multikinase inhibitors.

  2. These data suggested that miR34c3p acts as a tumor suppressor via regulation of MARCKS expression in OS progression

  3. Ca(2+)-PKC-MARCKS-PIP2-PI3K-PIP3 system functions as an activation module in vitro

  4. Findings show that calmodulin (CaM (显示 CALM1 PLURAL_@27095@)) stimulates phosphoinositide-3-kinase (PI3K (显示 PIK3CA PLURAL_@27095@)) lipid kinase activity by binding MARCKS and displacing it from phosphatidylinositol 4,5-bisphosphate (PIP2) headgroups, thereby releasing free PIP2 that recruits active PI3K (显示 PIK3CA PLURAL_@27095@) to the membrane and serves as the substrate for the generation of phosphatidylinositol 3,4,5-trisphosphate (PIP3).

  5. Findings suggest that MIR429 modulates mucin (显示 SLC13A2 抗体) secretion in human colorectal cells and mouse colitis tissues by up-regulating of MARCKS expression.

  6. Knockdown of MARCKS in HepG2 cells reduced cell migration and invasion, but not cell proliferation.

  7. MARCKS upregulation increases vascular smooth muscle cell motility by activation of Rac1 and Cdc42 (显示 CDC42 抗体), promoting neointima formation.

  8. A novel role for MARCKS in regulating nuclear functions such as gene expression.

  9. MARCKS knockdown arrested VSMC cell cycle by decreasing KIS (显示 UHMK1 抗体) expression. Decreased KIS (显示 UHMK1 抗体) expression resulted in nuclear trapping of p27kip1 (显示 CDKN1B 抗体) in VSMCs.

  10. unresponsiveness of breast cancer to paclitaxel treatment is, at least in part, mediated by phospho-MARCKS

Cow (Bovine) Myristoylated Alanine-Rich Protein Kinase C Substrate (MARCKS) interaction partners

  1. MARCKS protein mediates hydrogen peroxide regulation of endothelial permeability.

  2. a critical role for H(2)O(2) in angiotensin-II signaling to the endothelial cytoskeleton in a novel pathway that is critically dependent on MARCKS, Rac1, and c-Abl.

  3. These findings demonstrate a critical role for MARCKS-phosphatidylinositol-4,5-diphosphate signaling in regulating dendrite development.

  4. Protein kinase C (显示 PKC 抗体) mediated inhibition of endothelial L-arginine (显示 GATM 抗体) transport is mediated by MARCKS protein

MARCKS 抗原简介

蛋白简介

The protein encoded by this gene is a substrate for protein kinase C. It is localized to the plasma membrane and is an actin filament crosslinking protein. Phosphorylation by protein kinase C or binding to calcium-calmodulin inhibits its association with actin and with the plasma membrane, leading to its presence in the cytoplasm. The protein is thought to be involved in cell motility, phagocytosis, membrane trafficking and mitogenesis.

Gene names and symbols associated with MARCKS

  • myristoylated alanine-rich protein kinase C substrate (marcks) 抗体
  • myristoylated alanine rich protein kinase C substrate (MARCKS) 抗体
  • methyl binding domain106 (mbd106) 抗体
  • myristoylated alanine-rich protein kinase C substrate S homeolog (marcks.S) 抗体
  • myristoylated alanine rich protein kinase C substrate (Marcks) 抗体
  • myristoylated alanine-rich protein kinase C substrate b (marcksb) 抗体
  • 80K-L 抗体
  • KINC 抗体
  • MACS 抗体
  • MARCKS 抗体
  • MGC89127 抗体
  • PKCSL 抗体
  • PRKCSL 抗体
  • wu:fb55c06 抗体
  • wu:fb92d04 抗体
  • wu:fc19b04 抗体
  • wu:fc44a10 抗体
  • zgc:110235 抗体

Protein level used designations for MARCKS

myristoylated alanine-rich protein kinase C substrate , methyl binding domain , Zmmbd2 , PCO124731 , PCO124731_ov , myristoylated alanine-rich C-kinase substrate , Myristoylated alanine-rich protein kinase C substrate , protein kinase C substrate 80 kDa protein , myristoylated alanine-rich protein kinase C substrate (MARCKS, 80K-L) , phosphomyristin , protein kinase C substrate, 80 kDa protein, light chain , myristoylated alanine-rich C kinase substrate (MARCKS) , ACAMP-81

GENE ID SPECIES
448317 Xenopus (Silurana) tropicalis
694077 Macaca mulatta
742020 Pan troglodytes
100345174 Oryctolagus cuniculus
542069 Zea mays
379767 Xenopus laevis
17118 Mus musculus
25603 Rattus norvegicus
323201 Danio rerio
4082 Homo sapiens
396473 Gallus gallus
613548 Bos taurus
612436 Canis lupus familiaris
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