Myocilin (MYOC) ELISA试剂盒

MYOC encodes the protein myocilin, which is believed to have a role in cytoskeletal function. 再加上,我们可以发Myocilin 抗体 (60)Myocilin 蛋白 (23)和数多这个蛋白质的别的产品。

list all ELISA KIts 基因 基因ID UniProt
小鼠 MYOC MYOC 17926 O70624
MYOC 4653 Q99972
大鼠 MYOC MYOC 81523 Q9R1J4
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0.039 U/mL 0.156-10 U/mL Typical standard curve 96 Tests Log in to see 15至18个工作日
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0.26 ng/mL 0.781 ng/mL - 50 ng/mL   96 Tests Log in to see 8至12个工作日
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适于 Myocilin 相互作用对的更多 ELISA 试剂盒

Mouse (Murine) Myocilin (MYOC) interaction partners

  1. mutant myocilin induces abnormal ECM (显示 MMRN1 ELISA试剂盒) accumulation in the ER of TM cells, which may be responsible for reduced outflow facility and IOP elevation in myocilin-associated glaucoma.

  2. Mutated myocilin and heterozygous Sod2 (显示 SOD2 ELISA试剂盒) deficiency act synergistically in a mouse model of open-angle glaucoma

  3. myocilin promotes cell proliferation and resistance to apoptosis via the ERK1/2 (显示 MAPK1/3 ELISA试剂盒) MAPK (显示 MAPK1 ELISA试剂盒) signaling pathway.

  4. Myocilin binds to ErbB2 (显示 ERBB2 ELISA试剂盒)/ErbB3 (显示 ERBB3 ELISA试剂盒), activates these receptors, and affects the downstream PI3K-AKT (显示 AKT1 ELISA试剂盒) signaling pathway

  5. Myocilin also stimulated osteogenic differentiation of wild-type MSCs, which was associated with activation of the p38 (显示 CRK ELISA试剂盒), Erk1/2 (显示 MAPK1/3 ELISA试剂盒), and JNK (显示 MAPK8 ELISA试剂盒) MAP kinase (显示 MAPK1 ELISA试剂盒) signaling pathways

  6. We suggest that intracellular myocilin plays a role as a regulator of muscle hypertrophy pathways, acting through the components of dystrophin (显示 DMD ELISA试剂盒) associated protein complex.

  7. The TIGR is implicated in resistance to oxidative stress. Despite the presence of a SOD motif, which is necessary for protection in mammalian cells, the protein is not a functional SOD, but might be involved in SOD activity.

  8. TIGR is a newly identified component of the CNS glial scar that is likely to contribute to neuronal regenerative failure characteristic of the mammalian CNS.

  9. Results do not support a causative role for increased MYOC levels or the MYOC gene in steroid-induced glaucoma.

  10. Results show that myocilin and gamma-synuclein interact and as a result, myocilin's properties are changed.

Human Myocilin (MYOC) interaction partners

  1. present work reveals that FOXC1 (显示 FOXC1 ELISA试剂盒) is an important regulator of exocytosis and establishes a new link between FOXC1 (显示 FOXC1 ELISA试剂盒) and MYOC-associated glaucoma

  2. The four detected MYOC mutations appeared to be associated with morphologic changes in the trabecular meshwork and the underlying pathogenesis of a subtype of familial primary open angle glaucoma.

  3. The mutations c.1456C < T (p.L486F) in MYOC and c.322G < A (p.V108I) in B4GALT3 (显示 B4GALT3 ELISA试剂盒) are likely responsible for the pathogenesis of Primary Open-angle Glaucoma in this family.

  4. Our findings demonstrated that MYOC cascade genetic testing for POAG allows identification of at-risk individuals at an early stage or even before signs of glaucoma are present. To our knowledge, this is the first study to demonstrate the clinical utility of predictive genetic testing for MYOC glaucoma.

  5. regulation by retinoic acid acts through the MYOC promoter which contains a critical cluster of four retinoic acid responsive (显示 GPRC5A ELISA试剂盒) elements (RAREs), with the RARE-DR2 presenting the strongest effect and binding the RARalpha (显示 RARA ELISA试剂盒)/RXRalpha (显示 RXRA ELISA试剂盒) heterodimer.

  6. Five out of 30 families with PCG (16.7%) had disease attributable to CYP1B1 (显示 CYP1B1 ELISA试剂盒) alterations suggesting that CYP1B1 (显示 CYP1B1 ELISA试剂盒) is not the major gene causing PCG in Vietnamese unlike in the case of Arab or Romany patients.

  7. The present study provides insight into the genetic or haplotype variants of MYOC and OPTN (显示 OPTN ELISA试剂盒) genes contributing to primary glaucoma. Haplotype variants identified in the present study may be regarded as potential contributing factors of primary glaucoma in Korea.

  8. Familial linkage studies for primary angle-closure glaucoma have been performed and identified MYOC causative primary angle-closure glaucoma disease

  9. The rate of CYP1B1 (显示 CYP1B1 ELISA试剂盒) mutations in Lebanese patients with primary congenital glaucoma (PCG) is lower than that reported in other Arab and Middle Eastern populations and suggests other genes are responsible.

  10. Data show that predictive genetic testing for early onset Myocilin glaucoma can facilitate early detection of disease or discharge from routine ophthalmic examinations.

Cow (Bovine) Myocilin (MYOC) interaction partners

  1. endoproteolytic processing might regulate the activity of myocilin; the inhibition of the processing by pathogenic mutations impairs the normal role of myocilin

Myocilin (MYOC) 抗原简介

Antigen Summary

MYOC encodes the protein myocilin, which is believed to have a role in cytoskeletal function. MYOC is expressed in many occular tissues, including the trabecular meshwork, and was revealed to be the trabecular meshwork glucocorticoid-inducible response protein (TIGR). The trabecular meshwork is a specialized eye tissue essential in regulating intraocular pressure, and mutations in MYOC have been identified as the cause of hereditary juvenile-onset open-angle glaucoma.

Gene names and symbols associated with Myocilin (MYOC) ELISA试剂盒

  • myocilin (MYOC) 抗体
  • myocilin (myoc) 抗体
  • myocilin (Myoc) 抗体
  • AI957332 抗体
  • GLC1A 抗体
  • GPOA 抗体
  • JOAG 抗体
  • JOAG1 抗体
  • MGC136645 抗体
  • MYOC 抗体
  • myocilin 抗体
  • Tigr 抗体
  • zgc:136645 抗体

Protein level used designations for Myocilin (MYOC) ELISA试剂盒

myocilin , trabecular meshwork-induced glucocorticoid response protein , mutated trabecular meshwork-induced glucocorticoid response protein

GENE ID SPECIES
397046 Sus scrofa
548602 Danio rerio
704406 Macaca mulatta
17926 Mus musculus
4653 Homo sapiens
81523 Rattus norvegicus
281342 Bos taurus
101087632 Felis catus
490344 Canis lupus familiaris
100008897 Oryctolagus cuniculus
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