anti-Myeloid/lymphoid Or Mixed-Lineage Leukemia (Trithorax Homolog, Drosophila), Translocated To, 11 (MLLT11) 抗体

The gene variously symbolized ALL1, HRX, or MLL located on 11q23 has been demonstrated to be fused with a number of translocation partners in cases of leukemia. 再加上,我们可以发MLLT11 蛋白 (8)和数多这个蛋白质的别的产品。

列出全部抗体 基因 基因ID UniProt
MLLT11 10962 Q13015
MLLT11 56772 P97783
MLLT11 295264 Q5M971
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Showing 10 out of 22 products:

产品编号 适用 宿主 标记 应用范围 图像 规格 供应商 交付 价格 详细
小鼠 非结合性 ELISA, WB Detection limit for recombinant GST tagged MLLT11 is approximately 0.03ng/ml as a capture antibody. Western Blot detection against Immunogen (35.64 KDa) . 100 μg Log in to see 11至12个工作日
$430.00
详细
非结合性 IF (p), IHC (p) Antigen: 0.2 µg/100 µL  Primary: Antiserum, 1:500, 1:1000, 1:2000, 1:4000, 1:8000, 1:16000, 1:32000;  Secondary: HRP conjugated Goat-Anti-Rabbit IgG at 1: 5000;  TMB staining;  Read the data in MicroplateReader by 450 100 μL Log in to see 3至7个工作日
$295.90
详细
小鼠 非结合性 ELISA, WB Detection limit for recombinant GST tagged MLLT11 is approximately 0.03 ng/mL as a capture antibody. 0.1 mg Log in to see 8至11个工作日
$450.00
详细
Cy5 IF (p)   100 μL Log in to see 14至21个工作日
$405.90
详细
Cy5.5 IF (p)   100 μL Log in to see 14至21个工作日
$405.90
详细
HRP IHC (p)   100 μL Log in to see 14至21个工作日
$405.90
详细
Cy3 IF (p)   100 μL Log in to see 14至21个工作日
$405.90
详细
Cy7 IF (p)   100 μL Log in to see 14至21个工作日
$405.90
详细
Alexa Fluor 350 IF (p)   100 μL Log in to see 14至21个工作日
$405.90
详细
FITC IF (p)   100 μL Log in to see 14至21个工作日
$405.90
详细

通过反应活性、应用领域、克隆类型和共轭标记 MLLT11 抗体

特性 应用范围 宿主 克隆类型 标记
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引用最多的anti-MLLT11 抗体

  1. Human Monoclonal MLLT11 Primary Antibody for ELISA, WB - ABIN564754 : Chang, Li, Hou, Wu, Lu, Di, Jin, Ou, Shen, Shao: Identification of the functional role of AF1Q in the progression of breast cancer. in Breast cancer research and treatment 2008 (PubMed)
    Show all 5 Pubmed References

更多抗MLLT11的相互作用对抗体

Human Myeloid/lymphoid Or Mixed-Lineage Leukemia (Trithorax Homolog, Drosophila), Translocated To, 11 (MLLT11) interaction partners

  1. These results suggest that AF1q would have a role as an enhancer in generation of stem-like population through activation of Wnt (显示 WNT2 抗体) signaling pathway.

  2. Findings indicate that breast cancer cells with a hyperactive AF1q/TCF7 (显示 TCF7 抗体)/CD44 (显示 CD44 抗体) regulatory axis in the primary sites may represent "metastatic founder cells" which have invasive properties.

  3. Results demonstrate that AF1q gene transcription is regulated by REST through direct binding at -383 to -363 bp of AF1q promoter.

  4. AF1Q had a KFERQ-like motif.

  5. AF1q plays a role in the onset of basal apoptosis in ovarian cancer cells, thus providing new information about the activity of this protein whose biologic functions are mostly unknown

  6. Using in vitro assays based on either forced expression or shRNA-mediated silencing of AF1q, the study provides evidence that the protein promotes T- over B-cell differentiation in multipotent hematopoietic progenitors.

  7. AF1q up-regulation of BAD is through its effect on NF-kappaB (显示 NFKB1 抗体) and this may hint of its oncogenic mechanism in cancer.

  8. The ectopic expression of human AF1q triggered the expression of the neuronal marker TuJ1 in non-neuronal human embryonic kidney (HEK) cells.

  9. overexpression of AF1Q leads to more progression in human breast cancer

  10. The study provides the first evidence that AF1q plays a critical role in the regulation of apoptosis and drug resistance.

Mouse (Murine) Myeloid/lymphoid Or Mixed-Lineage Leukemia (Trithorax Homolog, Drosophila), Translocated To, 11 (MLLT11) interaction partners

  1. MLLT11 is a pan (显示 SUPT6H 抗体)-neuronal marker, suggesting a role in neural differentiation in the central nervous system and neural crest-cell derived peripheral ganglia

  2. The mouse Af1q, homologue of human AF1q, was found to be significantly up-regulated during the neuronal production from neural stem cells

MLLT11 抗原简介

蛋白简介

The gene variously symbolized ALL1, HRX, or MLL located on 11q23 has been demonstrated to be fused with a number of translocation partners in cases of leukemia. t(1\;11)(q21\;q23) translocations that fused the MLL gene to a gene on chromosomal band 1q21 in 2 infants with acute myelomonocytic leukemia have been demonstrated. The N-terminal portion of the MLL gene is critical for leukemogenesis in translocations involving band 11q23. This gene encodes 90 amino acids. It was found to be highly expressed in the thymus but not in peripheral lymphoid tissues. In contrast to its restricted distribution in normal hematopoietic tissue, this gene was expressed in all leukemic cell lines tested.

Gene names and symbols associated with MLLT11

  • myeloid/lymphoid or mixed-lineage leukemia; translocated to, 11 (MLLT11) 抗体
  • MLLT11, transcription factor 7 cofactor (MLLT11) 抗体
  • myeloid/lymphoid or mixed-lineage leukemia; translocated to, 11 (Mllt11) 抗体
  • MLLT11, transcription factor 7 cofactor (Mllt11) 抗体
  • MLLT11, transcription factor 7 cofactor (mllt11) 抗体
  • Af1q 抗体
  • AI839562 抗体
  • fc23g02 抗体
  • RGD1305525 抗体
  • RP11-316M1.10 抗体
  • si:ch211-210h11.4 抗体
  • wu:fc23g02 抗体
  • Zfp692 抗体

Protein level used designations for MLLT11

protein AF1q , ALL1 fused gene from chromosome 1q , ALL1-fused gene from chromosome 1q , zinc finger protein 692 , AF1Q protein

GENE ID SPECIES
100520242 Sus scrofa
100682887 Canis lupus familiaris
10962 Homo sapiens
56772 Mus musculus
295264 Rattus norvegicus
539519 Bos taurus
100173899 Pongo abelii
563531 Danio rerio
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