anti-Myeloid/lymphoid Or Mixed-Lineage Leukemia (Trithorax Homolog, Drosophila), Translocated To, 1 (MLLT1) 抗体

Capable of activating transcription from synthetic reporter genes in both lymphoid and myeloid cells.. 再加上,我们可以发MLLT1 蛋白 (3)和数多这个蛋白质的别的产品。

列出全部抗体 基因 基因ID UniProt
MLLT1 301119  
MLLT1 4298 Q03111
MLLT1 64144  
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Showing 10 out of 41 products:

产品编号 适用 宿主 标记 应用范围 图像 规格 供应商 交付 价格 详细
Cow 非结合性 WB <b>WB Suggested Anti-MLLT1 Antibody Titration: </b>1.4ug/ml<br><b>Positive Control: </b>Raji cell lysate 100 μL Log in to see 2至3个工作日
$229.00
详细
非结合性 EIA, WB 0.4 mL Log in to see 6至8个工作日
$390.50
详细
非结合性 WB Western blot analysis of anti-MLLT1 Pab (ABIN390126) in A257 cell line lysate (35 µg/lane). MLLT1(arrow) was detected using the purified polyclonal antibody. 400 μL Log in to see 10至11个工作日
$324.50
详细
非结合性 ICC, IF, IHC, IHC (p) Immunohistochemistry-Paraffin: MLLT1 Antibody [NBP1-84840] - Staining of human hippocampus shows strong cytoplasmic and nucleolar positivity in neuronal cells. Immunocytochemistry/Immunofluorescence: MLLT1 Antibody [NBP1-84840] Staining of human cell line U-251MG shows positivity in nucleoli & nucleus but not nucleoli. 0.1 mL Log in to see 10至13个工作日
$439.69
详细
非结合性 WB 100 μg Log in to see 7至9个工作日
$493.17
详细
非结合性 ELISA, WB 100 μg Log in to see 2至3个工作日
$343.75
详细
非结合性 IHC (p), ELISA Human Brain, Cerebellum (formalin-fixed, paraffin-embedded) stained with MLLT1 antibody ABIN214673 at 5 ug/ml followed by biotinylated goat anti-rabbit IgG secondary antibody ABIN481713, alkaline phosphatase-streptavidin and chromogen. 50 μg Log in to see 7至9个工作日
$451.00
详细
非结合性 ICC, IF, IHC, IHC (p), IP, WB Immunohistochemistry-Paraffin: MLLT1 Antibody [NBP1-26653] - Section of human testicular seminoma. 0.1 mL Log in to see 7至9个工作日
$486.94
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非结合性 IP 100 μL Log in to see 7至9个工作日
$486.94
详细
非结合性 IHC, ELISA 0.05 mg Log in to see 2至3个工作日
$515.63
详细

通过反应活性、应用领域、克隆类型和共轭标记 MLLT1 抗体

特性 应用范围 宿主 克隆类型 标记
Rat (Rattus)


Human , , ,
,
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, , , , ,
Mouse (Murine)


引用最多的anti-MLLT1 抗体

  1. Human Polyclonal MLLT1 Primary Antibody for ICC, IF - ABIN4334892 : Perlman, Gadd, Arold, Radhakrishnan, Gerhard, Jennings, Huff, Guidry Auvil, Davidsen, Dome, Meerzaman, Hsu, Nguyen, Anderson, Ma, Mungall, Moore, Marra, Mullighan, Ma, Wheeler, Hampton et al.: MLLT1 YEATS domain mutations in clinically distinctive Favourable Histology Wilms tumours. ... in Nature communications 2015 (PubMed)

  2. Human Polyclonal MLLT1 Primary Antibody for WB - ABIN390126 : Bitoun, Oliver, Davies: The mixed-lineage leukemia fusion partner AF4 stimulates RNA polymerase II transcriptional elongation and mediates coordinated chromatin remodeling. in Human molecular genetics 2007 (PubMed)

更多抗MLLT1的相互作用对抗体

Human Myeloid/lymphoid Or Mixed-Lineage Leukemia (Trithorax Homolog, Drosophila), Translocated To, 1 (MLLT1) interaction partners

  1. data identify ENL as a histone acetylation reader that regulates oncogenic transcriptional programs in acute myeloid leukaemia, and suggest that displacement of ENL from chromatin may be a promising epigenetic therapy, alone or in combination with BET inhibitors, for aggressive leukaemia

  2. MLL (显示 MLL 抗体)-ENL dysregulated the proliferative and repopulating capacity of hematopoietic stem cells.

  3. Recurrent mutations within Wilms tumours involve the highly conserved YEATS domain of MLLT1.

  4. Novel splice isoform of Mllt1 is documented and confirmed that both Mllt1 mRNA isoforms are translated. The data support that MLLT1 protein isoforms display distinct stage-specific expression during spermiogenesis and adult tissues.

  5. Data suggest that AT mutated protein ATM (显示 ATM 抗体)-dependent phosphorylation of ENL (MLLT1) protein functions as switch from elongation to Polycomb (显示 CBX2 抗体)-mediated repression to preserve genome integrity.

  6. AF9 and its homolog ENL directly interact with AF4.

  7. MLL (显示 MLL 抗体)-ENL Interaction with CBX8 (显示 CBX8 抗体) Is Required for Efficient Transformation.

  8. Data from a follow-up study in Rome suggest a particularly favorable prognosis for patients with acute lymphoblastic leukemia expressing the MLL (显示 MLL 抗体)/ENL fusion gene.

  9. Three-way translocation involving MLL (显示 MLL 抗体), MLLT1, and a novel third partner, NRXN1 (显示 NRXN1 抗体), in a patient with acute lymphoblastic leukemia and t(2;19;11) (p12 (显示 POLE4 抗体);p13.3;q23).

  10. ENL chromatin-remodeling complexes contain a mixed-lineage leukemia chromosomal translocation partner.

Mouse (Murine) Myeloid/lymphoid Or Mixed-Lineage Leukemia (Trithorax Homolog, Drosophila), Translocated To, 1 (MLLT1) interaction partners

  1. data identify ENL as a histone acetylation reader that regulates oncogenic transcriptional programs in acute myeloid leukaemia, and suggest that displacement of ENL from chromatin may be a promising epigenetic therapy, alone or in combination with BET inhibitors, for aggressive leukaemia

  2. define a specific pairing of two amino acids that creates a salt bridge between MLLT1/3 and AFF proteins that is critically important for MLL (显示 MLL 抗体)-mediated transformation of HPCs

  3. demonstrate BAM11 transcriptional co-activation activity and its functional interaction with Btk (显示 BTK 抗体)

  4. An intimate association between MLL (显示 MLL 抗体) and RNA pol II (显示 POLR2F 抗体) occurs at MLL (显示 MLL 抗体) target genes in vivo that is required for normal initiation and/or transcriptional elongation.

  5. Overlapping expression of Af9 (显示 MLLT3 抗体) with Af4/Aff1 and Fmr2/Aff2 (显示 AFF2 抗体), two genes that are also related to neurodevelopmental diseases, as well as with the highly homologous Enl.

  6. Even genetically complex leukemias can be reversed on inactivation of the initiating MLL (显示 MLL 抗体) fusion.

MLLT1 抗原简介

蛋白简介

Capable of activating transcription from synthetic reporter genes in both lymphoid and myeloid cells.

Gene names and symbols associated with MLLT1

  • MLLT1, super elongation complex subunit (Mllt1) 抗体
  • MLLT1, super elongation complex subunit (MLLT1) 抗体
  • myeloid/lymphoid or mixed-lineage leukemia; translocated to, 1 L homeolog (mllt1.L) 抗体
  • myeloid/lymphoid or mixed-lineage leukemia; translocated to, 1 (mllt1) 抗体
  • myeloid/lymphoid or mixed-lineage leukemia; translocated to, 1 (Mllt1) 抗体
  • AA407901 抗体
  • BAM11 抗体
  • ENL 抗体
  • LTG19 抗体
  • MGC84026 抗体
  • MLLT1 抗体
  • YEATS1 抗体

Protein level used designations for MLLT1

myeloid/lymphoid or mixed lineage leukemia translocation to 1 homolog , myeloid/lymphoid or mixed lineage-leukemia translocation to 1 homolog , protein ENL , myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 1 , myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog); translocated to, 1 , ENL/MLL fusion , MLLT1/MLL fusion , YEATS domain-containing protein 1 , leukemia-associated protein MLLT1 , myeloid/lymphoid or mixed lineage-leukemia translocation to 4 homolog , trithorax

GENE ID SPECIES
301119 Rattus norvegicus
420089 Gallus gallus
447347 Xenopus laevis
485023 Canis lupus familiaris
504458 Bos taurus
702105 Macaca mulatta
740990 Pan troglodytes
100019539 Monodelphis domestica
100065400 Equus caballus
100158574 Xenopus (Silurana) tropicalis
4298 Homo sapiens
64144 Mus musculus
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