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MCFD2 抗体

(Multiple Coagulation Factor Deficiency 2 (MCFD2))

This gene encodes a soluble luminal protein with two calmodulin-like EF-hand motifs at its C-terminus. This protein forms a complex with LAMN1 (lectin mannose binding protein 1\; also known as ERGIC-53) that facilitates the transport of coagulation factors V (FV) and VIII (FVIII) from the endoplasmic reticulum to the Golgi apparatus via an endoplasmic reticulum Golgi intermediate compartment (ERGIC). Mutations in this gene cause combined deficiency of FV and FVIII (F5F8D)\; a rare autosomal recessive bleeding disorder characterized by mild to moderate bleeding and coordinate reduction in plasma FV and FVIII levels. This protein has also been shown to maintain stem cell potential in adult central nervous system and is a marker for testicular germ cell tumors. The 3' UTR of this gene contains a transposon-like human repeat element named 'THE 1'. A processed RNA pseudogene of this gene is on chromosome 6p22.1. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jun 2010].

recommended

MCFD2 抗体 (AA 1-146) (ABIN566639)

MCFD2 适用: 人 WB, ELISA, IHC (p), RNAi 宿主: 小鼠 Monoclonal 3A5-G4 unconjugated

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recommended

MCFD2 抗体 (ABIN4911821)

MCFD2 适用: 人 WB 宿主: 小鼠 Monoclonal 5C6 unconjugated

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recommended

MCFD2 抗体 (AA 1-146) (ABIN1327026)

MCFD2 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal X1 unconjugated

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MCFD2 抗体 by 适用

Find MCFD2 抗体 for a variety of species such as anti-Human MCFD2, anti-Rat MCFD2, anti-Mouse MCFD2. The species listed below are among those available. Click on a link to go to the corresponding products.

MCFD2 抗体 by 应用范围

Find MCFD2 抗体 validated for a specific application such as WB, ELISA, IF (cc), IF (p). Some of the available applications are listed below. Click on a link to go to the corresponding products.

MCFD2 抗体 by 抗体来源

Find MCFD2 抗体 with a specific 抗体来源. The 抗体来源 listed below are among those available. Click on a link to go to the corresponding products.

MCFD2 抗体 by 抗原表位

Find MCFD2 抗体 with a specific epitope. The epitopes listed below are among those available. Click on a link to go to the corresponding products.

MCFD2 抗体 by 克隆形成能力

Find available monoclonal or polyclonal MCFD2 抗体. Click on a link to go to the corresponding products.

MCFD2 抗体 by 克隆

Find MCFD2 抗体 with a specific 克隆. The 克隆 listed below are among those available. Click on a link to go to the corresponding products.

MCFD2 抗体 by 标记

Find MCFD2 抗体 with a specific conjugate such as Biotin, FITC, HRP. The conjugates listed below are among those available. Click on a link to go to the corresponding products.

Popular MCFD2 抗体

Product

Reactivity

Application

Validations

Cat. No.

Quantity

Datasheet

anti-MCFD2 抗体 (AA 1-146)

Reactivity Human

Application WB, ELISA, IHC (p), RNAi

Validations

Cat. No. ABIN566639

Quantity 100 μg

Datasheet Datasheet

anti-MCFD2 抗体

Reactivity Human

Application WB

Validations

Cat. No. ABIN4911821

Quantity 100 μL

Datasheet Datasheet

anti-MCFD2 抗体 (AA 1-146)

Reactivity Human

Application WB, ELISA, IF

Validations

Cat. No. ABIN1327026

Quantity 100 μg

Datasheet Datasheet

anti-MCFD2 抗体 (AA 27-146)

Reactivity Human

Application WB, IHC

Validations

Cat. No. ABIN6143636

Quantity 100 μL

Datasheet Datasheet

anti-MCFD2 抗体

Reactivity Human

Application WB, ELISA

Validations

Cat. No. ABIN3028852

Quantity 0.4 mL

Datasheet Datasheet

anti-MCFD2 抗体 (AA 1-100)

Reactivity Mouse, Rat

Application WB, IF (cc), IF (p), IHC (p), IHC (fro), ICC

Validations

Cat. No. ABIN6989560

Quantity 100 μL

Datasheet Datasheet

anti-MCFD2 抗体 (AA 1-100) (Biotin)

Reactivity Mouse, Rat

Application WB, IHC (p), IHC (fro)

Validations

Cat. No. ABIN6982994

Quantity 100 μL

Datasheet Datasheet

anti-MCFD2 抗体 (AA 1-100) (Alexa Fluor 350)

Reactivity Mouse, Rat

Application WB, IF (cc), IF (p)

Validations

Cat. No. ABIN6977118

Quantity 100 μL

Datasheet Datasheet

anti-MCFD2 抗体 (AA 1-100) (Alexa Fluor 555)

Reactivity Mouse, Rat

Application WB, IF (cc), IF (p)

Validations

Cat. No. ABIN6978840

Quantity 100 μL

Datasheet Datasheet

anti-MCFD2 抗体 (AA 1-100) (Alexa Fluor 488)

Reactivity Mouse, Rat

Application WB, IF (cc), IF (p)

Validations

Cat. No. ABIN6977979

Quantity 100 μL

Datasheet Datasheet

anti-MCFD2 抗体 (AA 1-100) (Alexa Fluor 594)

Reactivity Mouse, Rat

Application WB, IF (cc), IF (p)

Validations

Cat. No. ABIN6979635

Quantity 100 μL

Datasheet Datasheet

anti-MCFD2 抗体 (AA 1-100) (Alexa Fluor 647)

Reactivity Mouse, Rat

Application WB, IF (cc), IF (p)

Validations

Cat. No. ABIN6980494

Quantity 100 μL

Datasheet Datasheet

anti-MCFD2 抗体 (AA 1-100) (Alexa Fluor 680)

Reactivity Mouse, Rat

Application WB, IF (cc), IF (p)

Validations

Cat. No. ABIN6981410

Quantity 100 μL

Datasheet Datasheet

anti-MCFD2 抗体 (AA 1-100) (Alexa Fluor 750)

Reactivity Mouse, Rat

Application WB, IF (cc), IF (p)

Validations

Cat. No. ABIN6982382

Quantity 100 μL

Datasheet Datasheet

anti-MCFD2 抗体 (AA 1-100) (Cy3)

Reactivity Mouse, Rat

Application WB, IF (cc), IF (p)

Validations

Cat. No. ABIN6983916

Quantity 100 μL

Datasheet Datasheet

Latest Publications for our MCFD2 抗体

Nyfeler, Zhang, Ginsburg, Kaufman, Hauri: "Cargo selectivity of the ERGIC-53/MCFD2 transport receptor complex." in: Traffic (Copenhagen, Denmark), Vol. 7, Issue 11, pp. 1473-81, (2006) (PubMed).

Mohanty, Ghosh, Shetty, Spreafico, Garagiola, Peyvandi: "Mutations in the MCFD2 gene and a novel mutation in the LMAN1 gene in Indian families with combined deficiency of factor V and VIII." in: American journal of hematology, Vol. 79, Issue 4, pp. 262-6, (2005) (PubMed).

Zhang, Kaufman, Ginsburg: "LMAN1 and MCFD2 form a cargo receptor complex and interact with coagulation factor VIII in the early secretory pathway." in: The Journal of biological chemistry, Vol. 280, Issue 27, pp. 25881-6, (2005) (PubMed).

Aliases for MCFD2 抗体

multiple coagulation factor deficiency 2 (MCFD2) 抗体
multiple coagulation factor deficiency 2 (mcfd2) 抗体
multiple coagulation factor deficiency 2 L homeolog (mcfd2.L) 抗体
multiple coagulation factor deficiency 2 (Mcfd2) 抗体
1810021C21Rik 抗体
DKFZp469B098 抗体
F5F8D 抗体
F5f8d 抗体
F5F8D2 抗体
hm:zeh1186 抗体
LMAN1IP 抗体
Lman1ip 抗体
MCFD2 抗体
SDNSF 抗体
Sdnsf 抗体
wu:fc23b10 抗体
wu:fd50d08 抗体
zgc:103713 抗体
zgc:109915 抗体

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Popular MCFD2 抗体

Latest Publications for our MCFD2 抗体

Aliases for MCFD2 抗体

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