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This is a nuclear gene encoding a protein that functions in mitochondrial and peroxisomal fission. 再加上，我们可以发Mitochondrial Fission Factor 抗体 (56) 和 Mitochondrial Fission Factor 蛋白 (7)和数多这个蛋白质的别的产品。
We suggest that, even if laboratory findings are not indicative of mitochondrial or peroxisomal dysfunction, the co-occurrence of optic and/or peripheral neuropathy with seizures warrants genetic testing for MFF mutations
membrane-anchored Mff differentially regulates various Drp1 (显示 CRMP1 ELISA试剂盒) isoforms.
Data show that expression of MFF protein, miR-593-5p and BRCA1 protein correlates with cisplatin sensitivity and survival of tongue squamous cell carcinoma (TSCC).
loss of Mff results in failure of Parkin (显示 PARK2 ELISA试剂盒) translocation and final clearance of damaged mitochondria
Mitochondrial fission factor (MFF) mRNA is a direct target of miR (显示 MLXIP ELISA试剂盒)-27, whose ectopic expression decreases MFF expression through binding to its 3'-untranslated region.
MiD49 (显示 SMCR7 ELISA试剂盒) and MiD51 (显示 SMCR7L ELISA试剂盒) can act independently of Mff and Fis1 (显示 FIS1 ELISA试剂盒) in Drp1 (显示 CRMP1 ELISA试剂盒) recruitment and suggest that they provide specificity to the division of mitochondria.
TRAP1 (显示 TRAP1 ELISA试剂盒) controls mitochondrial fusion/fission balance through Drp1 (显示 CRMP1 ELISA试剂盒) and Mff expression.
PEX11 proteins attract both Mff and human Fis1 (hFis1 (显示 FIS1 ELISA试剂盒)) to their site of action.
MFF over-expression results in extensive mitochondrial fragmentation, driving mitochondrial dysfunction. MFF fibroblasts undergo oxidative stress, with increased ROS (显示 ROS1 ELISA试剂盒) production, and the onset of autophagy and mitophagy.
MFF gene expression is decreased in both classic and follicular variants of papillary thyroid carcinoma.
MiD51 (显示 SMCR7L ELISA试剂盒) can suppress Mff-dependent enhancement of Drp1 (显示 CRMP1 ELISA试剂盒) GTPase (显示 RACGAP1 ELISA试剂盒) activity.
Mff cannot bind to assembly-deficient mutants of Drp1 (显示 CRMP1 ELISA试剂盒), suggesting that Mff selectively interacts with higher-order complexes of Drp1 (显示 CRMP1 ELISA试剂盒).
These findings provide a mechanism wherein the multimeric states of both Mff and Drp1 (显示 CRMP1 ELISA试剂盒) regulate their collaborative interaction.
Ablating Mfn1 (显示 MFN1 ELISA试剂盒) eliminates the cardiac-related lethality of Mff knockout mice.
Mitochondrial fission factor has been identified as a new AMPK (显示 PRKAA1 ELISA试剂盒) substrate.
This study reveals a novel model of mitochondrial fission regulation, which is composed of miR (显示 MLXIP ELISA试剂盒)-761 and mitochondrial fission factor
immunofluorescence analysis of Drp1 (显示 CRMP1 ELISA试剂盒) suggests that Fis1 (显示 FIS1 ELISA试剂盒) and Mff are important for the number and size of Drp1 (显示 CRMP1 ELISA试剂盒) puncta on mitochondria.
This is a nuclear gene encoding a protein that functions in mitochondrial and peroxisomal fission. The encoded protein recruits dynamin-1-like protein (DNM1L) to mitochondria. There are multiple pseudogenes for this gene on chromosomes 1, 5, and X. Alternative splicing results in multiple transcript variants.
mitochondrial fission factor homolog B
, mitochondrial fission factor homolog A
, mitochondrial fission factor
, Uncharacterized protein C2orf33 homolog