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anti-Microtubule-Associated Protein 1 Light Chain 3 beta (MAP1LC3B) 抗体

The product of MAP1LC3B is a subunit of neuronal microtubule-associated MAP1A and MAP1B proteins, which are involved in microtubule assembly and important for neurogenesis. 再加上,我们可以发Microtubule-Associated Protein 1 Light Chain 3 beta 蛋白 (15)Microtubule-Associated Protein 1 Light Chain 3 beta 试剂盒 (12)和数多这个蛋白质的别的产品。

列出全部抗体 基因 基因ID UniProt
MAP1LC3B 100361973  
MAP1LC3B 81631 Q9GZQ8
MAP1LC3B 67443 Q9CQV6

antibodies-online.cn销售最多的anti-Microtubule-Associated Protein 1 Light Chain 3 beta 抗体

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产品编号 适用 宿主 标记 应用范围 图像 规格 供应商 交付 价格 详细
非结合性 DB Dot blot analysis of Phospho-LC3 (APG8b)- T12 Antibody (ABIN389913) on nitrocellulose membrane.  50 ng of Phospho-peptide or Non Phospho-peptide per dot were adsorbed. Antibody working concentrations are 0.5 µg/mL. Immunofluorescence confocal microscopy staining of LC3B. (I) Control cells treated with PBS and serum, (II) PMA-treated cells. 1. DAPI: blue, 2. LC3B: red and 3. merge. 400 μL Log in to see 9至13个工作日
¥2,325.14
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非结合性 ICC, IF Time course study of mouse leukaemic monocyte macrophage cells treated with U18666A, a drug that causes cholesterol and lipid storage in cells, thereby blocking fusion between late endosomes and lysosomes. Cleaved-LC3 (APG8b) antibody (ABIN388484) detected punctuate staining indicative of autophagic vacuole or phagosome structures. Data courtesy of Dr. Barry Boland, Department of Pharmacology, Oxford University. SY5Y cells were pretreated with 5nM bafilomycin for 24hr and fixed in methanol (left panel) or 4% of paraformaldehyde (right panel). Treatment with ABIN388484 antibody at dilution 1:100. Data courtesy of Jianhui Zhu, MD, PhD & Charleen T. Chu, MD, PhD, University of Pittsburgh School of Medicine. 400 μL Log in to see 9至13个工作日
¥2,606.76
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非结合性 FACS, ICC, IF, IHC, IHC (p), IP, WB Immunocytochemistry/Immunofluorescence: LC3B/MAP1LC3B Antibody (1251A) [NBP2-46892] - HeLa cells were treated with 50 uM Chloroquine for 24 hour prior to fixation in 10% buffered formalin for 10 min. Cells were permeabilized in 0.1% Triton X-100 and incubated with 20 ug/ml anti-LC3B (1251A) and 1:500 anti-tubulin ABIN4330478) for 1 h at room temperature. LC3 reactivity (green) was detected with ant-rabbit Dylight 488 and tubulin (red) with anti-mouse Dylight 550. Nuclei were counterstained with DAPI (blue). Immunohistochemistry-Paraffin: LC3B/MAP1LC3B Antibody (1251A) [NBP2-46892] - IHC analysis of a formalin fixed and paraffin embedded tissue section of normal mouse brain using rabbit monoclonal LC3B (1251A) antibody at 1:100 dilution with HRP-DAB detection. The antibody generated a weak diffused cytoplasmic staining in most of the cells but some cells, especially within empty areas on the section, showed punctate signal also which signifies the presence of autophagy in those areas. 0.1 mg Log in to see 25至31个工作日
¥3,119.56
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非结合性 EIA, IF, IHC (p), WB FACS sorted LSK cells (Lineage-Sca-1+c-kit+, enriched for hematopoietic stem cells) incubated with LC3B Antibody at 1/50 dilution at 4 degree overnight., and detected with Alexa Fluor 488 conjugated anti-Rabbit antibody (1/200). Data courtesy of Wenbin Xiao, La Jolla Institute for Allergy and Immunology. Immunofluorescence analysis of LC3B Antibody  in Rat brain before (left) and after (right) treatment with rapamycin (100 nm for 4 hr). 0.4 mL Log in to see 29至35个工作日
¥3,632.23
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非结合性 EIA, WB Western blot analysis of LC3B Antibody Western blot analysis of MAP1LC3B (arrow) using LC3B Antibody (T6) in Y79 cell line lysates and mouse brain tissue lysates (35 µg/lane). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the MAP1LC3B gene (Lane 2) (Origene Technologies). 0.4 mL Log in to see 29至35个工作日
¥4,086.26
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非结合性 EIA, IF SY5Y cells were pretreated with 5nM bafilomycin for 24hr and fixed in methanol (left panel) or 4% of paraformaldehyde (right panel). Treatment with Cleaved-LC3B Antibody (APG8b) Cat.-No AP32168PU-N at dilution 1/100. Data courtesy of Jianhui Zhu, MD, PhD & Charleen T. Chu, MD, PhD, University of Pittsburgh School of Medicine. Time course study of mouse leukaemic monocyte macrophage cells treated with U18666A, a drug that causes cholesterol and lipid storage in cells, thereby blocking fusion between late endosomes and lysosomes. Cleaved-LC3B Antibody (APG8b) Cat.-No AP32168PU-N detected punctuate staining indicative of autophagic vacuole or phagosome structures. Data courtesy of Dr. Barry Boland, Department of Pharmacology, Oxford University. 0.4 mL Log in to see 29至35个工作日
¥4,086.26
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非结合性 DB, EIA Dot blot analysis of Phospho-LC3 (APG8b)- Thr12 Antibody  on nitrocellulose membrane. 50ng of Phospho-peptide or Non Phospho-peptide per dot were adsorbed. Antibody working concentrations are 0.5 µg/ml. 0.4 mL Log in to see 29至35个工作日
¥4,086.26
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非结合性 EIA, IHC (p), WB Formalin-Fixed, Paraffin-Embedded human cancer tissue reacted with LC3B Antibody (C-term) followed which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. Formalin-Fixed, Paraffin-embedded human testis tissue reacted with Autophagy LC3B Antibody (C-term) followed which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. 0.4 mL Log in to see 29至35个工作日
¥4,086.26
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Cow 非结合性 EM, FACS, ICC, IF, IHC, IHC (fro), IHC (p), SimWes, WB Detection of LC3B in treated U87-MG (human glioblastoma astrocytoma) lysates using ABIN153145. Staining of treated U373-MG (human glioblastoma) cells using ABIN153145. 0.1 mL Log in to see 25至31个工作日
¥3,869.96
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Bacteria 非结合性 ELISA, ICC, IF, IHC, IHC (fro), IHC (p), IP, PLA, SimWes, WB Western Blot: LC3 Antibody [ABIN250638SS] - Detection of LC3 in human brain lysate using ABIN250638. Atg5-/- ES cells from Dr. Noboru Mizushima [Mizushima, N. et al. J. Cell Biol. 152 (2001)] Photo courtesy of Dr. Beth Levine, UT Southwestern Medical Center Imnmunohistochemistry: LC3 Antibody [ABIN250638SS] - Staining of brain, cerebral cortex, neurons with cell processes using ABIN250638. 0.1 mL Log in to see 25至31个工作日
¥3,977.17
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通过反应活性、应用领域、克隆类型和共轭标记 MAP1LC3B 抗体

特性 应用范围 宿主 克隆类型 标记
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引用最多的anti-Microtubule-Associated Protein 1 Light Chain 3 beta 抗体

  1. Bacteria Polyclonal MAP1LC3B Primary Antibody for ELISA, ICC - ABIN250638 : Sarkar, Krishna, Imarisio, Saiki, OKane, Rubinsztein: A rational mechanism for combination treatment of Huntington's disease using lithium and rapamycin. in Human molecular genetics 2008 (PubMed)
    Show all 523 references for ABIN250638

  2. Cow (Bovine) Polyclonal MAP1LC3B Primary Antibody for EM, FACS - ABIN153145 : Pyo, Nah, Kim, Lee, Heo, Lee, Jung: Compensatory activation of ERK1/2 in Atg5-deficient mouse embryo fibroblasts suppresses oxidative stress-induced cell death. in Autophagy 2008 (PubMed)
    Show all 156 references for ABIN153145

  3. Human Polyclonal MAP1LC3B Primary Antibody for EIA, IF - ABIN1449599 : Wartosch, Fuhrmann, Schweizer, Stauber, Jentsch: Lysosomal degradation of endocytosed proteins depends on the chloride transport protein ClC-7. in FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2009 (PubMed)
    Show all 15 references for ABIN1449599

  4. Human Polyclonal MAP1LC3B Primary Antibody for EIA, IF - ABIN1449601 : Checinska, Soengas: The gluttonous side of malignant melanoma: basic and clinical implications of macroautophagy. in Pigment cell & melanoma research 2011 (PubMed)
    Show all 11 references for ABIN1449601

  5. Human Polyclonal MAP1LC3B Primary Antibody for ICC, IF - ABIN388484 : English, Chemali, Duron, Rondeau, Laplante, Gingras, Alexander, Leib, Norbury, Lippé, Desjardins: Autophagy enhances the presentation of endogenous viral antigens on MHC class I molecules during HSV-1 infection. in Nature immunology 2009 (PubMed)
    Show all 11 references for ABIN388484

  6. Human Polyclonal MAP1LC3B Primary Antibody for DB, EIA - ABIN1449629 : Baehrecke: Autophagy: dual roles in life and death? in Nature reviews. Molecular cell biology 2005 (PubMed)
    Show all 8 references for ABIN1449629

  7. Human Polyclonal MAP1LC3B Primary Antibody for EIA, WB - ABIN1449635 : Lum, DeBerardinis, Thompson: Autophagy in metazoans: cell survival in the land of plenty. in Nature reviews. Molecular cell biology 2005 (PubMed)
    Show all 8 references for ABIN1449635

  8. Human Polyclonal MAP1LC3B Primary Antibody for EIA, IHC (p) - ABIN1449627 : Ren, He, Nong, Zhu, Hu, Zhang, Huang, Zhu, Wu: Acquired cisplatin resistance in human lung adenocarcinoma cells is associated with enhanced autophagy. in Cancer biotherapy & radiopharmaceuticals 2010 (PubMed)
    Show all 7 references for ABIN1449627

  9. Human Polyclonal MAP1LC3B Primary Antibody for DB - ABIN389913 : Shintani, Klionsky: Autophagy in health and disease: a double-edged sword. in Science (New York, N.Y.) 2004 (PubMed)
    Show all 6 references for ABIN389913

  10. Human Monoclonal MAP1LC3B Primary Antibody for ICC, IF - ABIN4330478 : Wechman, Rao, Cheng, Gomez-Gutierrez, McMasters, Zhou: Development of an Oncolytic Adenovirus with Enhanced Spread Ability through Repeated UV Irradiation and Cancer Selection. in Viruses 2016 (PubMed)

更多抗Microtubule-Associated Protein 1 Light Chain 3 beta的相互作用对抗体

Pig (Porcine) Microtubule-Associated Protein 1 Light Chain 3 beta (MAP1LC3B) interaction partners

  1. Data indicate that the expression of MAP1LC3A (显示 MAP1LC3A 抗体), B and autophagy-associated genes (ATG5 (显示 ATG5 抗体), mTOR (显示 FRAP1 抗体), Beclin-1 (显示 BECN1 抗体)) was increased in normal pigs, while decreased in miniature pigs.

Human Microtubule-Associated Protein 1 Light Chain 3 beta (MAP1LC3B) interaction partners

  1. Low expression of MAP1LC3B is associated with lymph node metastasis in gastric cancer.

  2. Poly C binding protein 1 represses autophagy through downregulation of LC3B to promote tumor cell apoptosis in starvation

  3. BAG3 (显示 BAG3 抗体) maintains the basal amount of LC3B protein by controlling the translation of its mRNA in HeLa and HEK293 cells.

  4. Among the 101 patients, the frequency of high expression of beclin-1 (显示 BECN1 抗体) was 31.7% (32/101) and that of LC3b was 46.5% (47/101). A pathologic complete response was inversely associated with LC3b expression (P = 0.003) and alterations in the expression of autophagy-related proteins

  5. Collectively, our findings indicate that MIR494 reduces cell survival in 769-P renal cancer cells which is accompanied by increased lipid droplet formation (which occurs in a LC3B-dependent manner) and mitochondrial changes.

  6. Data show CGK733 induced microtubule associated protein LC3B formation upstream of AMP-activated protein kinase (显示 PRKAA2 抗体) and protein kinase (显示 CDK7 抗体) RNA-like endoplasmic reticulum kinase/CCAAT-enhancer-binding protein homologous protein (显示 DDIT3 抗体) pathways and p21 Cip1 (显示 CDKN1A 抗体) expression.

  7. the combined positivity for LC3B(+) puncta and nuclear HMGB1 (显示 HMGB1 抗体) is a positive predictor for longer BC survival

  8. In microsatellite stable carcinomas, the level of LC3B-II expression was higher than that in the microsatellite unstable carcinomas.

  9. Loss of HPS1 (显示 HPS1 抗体) protein results in impaired autophagy that is restored by exogenous LC3B and that defective autophagy might therefore play a critical role in the development and progression of Hermansky-Pudlak syndrome.

  10. FYCO1 (显示 FYCO1 抗体) requires a functional LC3A (显示 MAP1LC3A 抗体)/B-preferring LC3 (显示 MAP1LC3A 抗体)-interacting Region (LIR (显示 CD300C 抗体)) motif to facilitate efficient maturation of autophagosomes under basal conditions, whereas starvation-induced autophagy was unaffected

Mouse (Murine) Microtubule-Associated Protein 1 Light Chain 3 beta (MAP1LC3B) interaction partners

  1. MREG (显示 MREG 抗体)-dependent processing links both autophagic and phagocytic processes in LC3 (显示 MAP1LC3A 抗体)-associated phagocytosis. MREG (显示 MREG 抗体) participates in coordinating the association of phagosomes with LC3 (显示 MAP1LC3A 抗体) for content degradation with the MREG (显示 MREG 抗体) loss leading to phagosome accumulation.

  2. This work identifies a previously unrecognized role for alphav and the autophagy components LC3 and atg5 in regulating TLR signalling and B-cell immunity.

  3. Deficiency of autophagy protein Map1 (显示 MOAP1 抗体)-LC3b mediates IL-17 (显示 IL17A 抗体)-dependent lung pathology during respiratory viral infection via ER stress-associated IL-1 (显示 IL1A 抗体).

  4. This study suggests that autophagy could play a role in placental invasion system and that nutrient starvation affects LC3B expression.

  5. Data indicate that the recombinant plasmid encoding pCMV-LC3 (显示 MAP1LC3A 抗体)-LpqH could be a practical strategy for the development of improved vaccines against Mycobacterium tuberculosis.

  6. Lipidation of the LC3 (显示 MAP1LC3A 抗体)/GABARAP (显示 GABARAP 抗体) family of autophagy proteins relies on a membrane-curvature-sensing domain in Atg3 (显示 ATG3 抗体).

  7. p62 (显示 GTF2H1 抗体)/LC3b complex regulates lung alveolar epithelial cell homeostasis and cytoprotection after hyperoxia.

  8. Lc3 (显示 MAP1LC3A 抗体) over-expression improves survival and attenuates lung injury through increasing autophagosomal clearance in septic mice.

  9. LC3B plays a regulatory role in hyperoxia-induced epithelial apoptosis

  10. The model and biochemical data provide a rationale for Atg7 (显示 ATG7 抗体) dimerization: Atg8 is transferred in trans from the catalytic cysteine of one Atg7 (显示 ATG7 抗体) protomer to Atg3 (显示 ATG3 抗体) bound to the N-terminal domain of the opposite Atg7 (显示 ATG7 抗体) protomer within the homodimer.

Microtubule-Associated Protein 1 Light Chain 3 beta (MAP1LC3B) 抗原简介

蛋白简介

The product of this gene is a subunit of neuronal microtubule-associated MAP1A and MAP1B proteins, which are involved in microtubule assembly and important for neurogenesis. Studies on the rat homolog implicate a role for this gene in autophagy, a process that involves the bulk degradation of cytoplasmic component.

Gene names and symbols associated with MAP1LC3B

  • microtubule-associated protein 1 light chain 3 beta (map1lc3b) 抗体
  • microtubule-associated protein 1 light chain 3 beta (MAP1LC3B) 抗体
  • microtubule-associated protein 1 light chain 3 beta (LOC100361973) 抗体
  • microtubule-associated protein 1 light chain 3 beta (Map1lc3b) 抗体
  • 1010001C15Rik 抗体
  • Atg8 抗体
  • ATG8F 抗体
  • LC3b 抗体
  • MAP1A/1BLC3 抗体
  • Map1lc3 抗体
  • MAP1LC3B 抗体
  • MAP1LC3B-a 抗体
  • MGC76283 抗体
  • Mpl3 抗体
  • wu:fb60g11 抗体
  • zbs559 抗体
  • zgc:56434 抗体

Protein level used designations for MAP1LC3B

microtubule-associated proteins 1A/1B light chain 3B , Lc3 , microtubule-associated protein 1 light chain 3 beta , MAP1 light chain 3-like protein 2 , MAP1A/MAP1B LC3 B , MAP1A/MAP1B light chain 3 B , autophagy-related ubiquitin-like modifier LC3 B , autophagy-related protein LC3 B , MAP1A/1B light chain 3 B , microtubule-associated proteins 1A/1B light chain 3

GENE ID SPECIES
322425 Danio rerio
394972 Xenopus (Silurana) tropicalis
427559 Gallus gallus
479619 Canis lupus familiaris
733220 Xenopus laevis
746157 Pan troglodytes
100361973 Rattus norvegicus
100462754 Sus scrofa
81631 Homo sapiens
67443 Mus musculus
64862 Rattus norvegicus
408001 Bos taurus
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