Methylenetetrahydrofolate Dehydrogenase (NADP+ Dependent) 1-Like (MTHFD1L) ELISA试剂盒

The protein encoded by MTHFD1L is involved in the synthesis of tetrahydrofolate (THF) in the mitochondrion. 再加上,我们可以发MTHFD1L 抗体 (36)MTHFD1L 蛋白 (4)和数多这个蛋白质的别的产品。

list all ELISA KIts 基因 基因ID UniProt
MTHFD1L 25902 Q6UB35
大鼠 MTHFD1L MTHFD1L 361472  
MTHFD1L 270685 Q3V3R1
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适于 MTHFD1L 相互作用对的更多 ELISA 试剂盒

Human Methylenetetrahydrofolate Dehydrogenase (NADP+ Dependent) 1-Like (MTHFD1L) interaction partners

  1. study identifies MTHFD1L in the folate cycle as an important metabolic pathway in cancer cells with the potential for therapeutic targeting

  2. Studies reported that the A allele of a polymorphism in a gene involved in folate metabolism, MTHFD1L, showed a genome-wide significant association with late-onset Alzheimer's Disease.

  3. rs6922269 variant at MTHFD1L gene could be an important prognostic factor for cardiovascular mortality in patients after ACS (显示 PLA2G15 ELISA试剂盒).

  4. MTHFD1L rs6922269 genotype is associated with active vitamin B12 (显示 NDUFB3 ELISA试剂盒) levels at baseline and may be a marker of prognostic risk in patients with established coronary heart disease.

  5. Results indicate that miR (显示 MLXIP ELISA试剂盒)-9 and MiR (显示 MLXIP ELISA试剂盒)-197 specifically downregulate MTHFD1L in HEK293 and MCF-7 cells and that SNPrs7646 affects miR (显示 MLXIP ELISA试剂盒)-197 binding to the MTHFD1L 3' UTR (显示 UTS2R ELISA试剂盒) causing gene repression in the presence of the allele associated with neural tube defects.

  6. The rs3832406 polymorphism was associated with isolated cleft lip with or without cleft palate.(MTHFD1L)

  7. This study support a role of MTHFD1L gene in late-onset Alzheimer's disease in a Northern Han Chinese population.

  8. No evidence of association between the MTHFD1L marker and susceptibility to Alzheimer's disease is found in a sample from a Spanish population.

  9. Prevalence of minor allele A (adenosine) in rs11754661 single nucleotide polymorphism of MTHFD1L contributes to the risk of Alzheimer's disease in a Han population of mainland China.

  10. mitochondrial C1-tetrahydrofolate synthase (显示 MTHFD1 ELISA试剂盒) gene structure and tissue distribution

Mouse (Murine) Methylenetetrahydrofolate Dehydrogenase (NADP+ Dependent) 1-Like (MTHFD1L) interaction partners

  1. Deletion of Mthfd1l causes embryonic lethality and neural tube and craniofacial defects in mice.

  2. Data show that the MTHFD1L enzyme is present in mitochondria from normal embryonic tissues and embryonic fibroblast cell lines, and embryonic mitochondria possess the ability to synthesize formate from glycine.

MTHFD1L 抗原简介

Antigen Summary

The protein encoded by this gene is involved in the synthesis of tetrahydrofolate (THF) in the mitochondrion. THF is important in the de novo synthesis of purines and thymidylate and in the regeneration of methionine from homocysteine. Several transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with MTHFD1L

  • methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1 like (MTHFD1L) 抗体
  • methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like (Mthfd1l) 抗体
  • 2410004L15Rik 抗体
  • AI647056 抗体
  • dJ292B18.2 抗体
  • Fthfsdc1 抗体
  • MTC1THFS 抗体

Protein level used designations for MTHFD1L

10-formyl-THF synthetase , formyltetrahydrofolate synthetase domain containing 1 , monofunctional C1-tetrahydrofolate synthase, mitochondrial , formyltetrahydrofolate synthetase

GENE ID SPECIES
25902 Homo sapiens
361472 Rattus norvegicus
476245 Canis lupus familiaris
534296 Bos taurus
270685 Mus musculus
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