anti-Methylenetetrahydrofolate Dehydrogenase (NADP+ Dependent) 1-Like (MTHFD1L) 抗体

The protein encoded by MTHFD1L is involved in the synthesis of tetrahydrofolate (THF) in the mitochondrion. 再加上,我们可以发MTHFD1L 试剂盒 (4)MTHFD1L 蛋白 (4)和数多这个蛋白质的别的产品。

列出全部抗体 基因 基因ID UniProt
MTHFD1L 25902 Q6UB35
MTHFD1L 361472  
MTHFD1L 270685 Q3V3R1
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Showing 10 out of 36 products:

产品编号 适用 宿主 标记 应用范围 图像 规格 供应商 交付 价格 详细
小鼠 非结合性 WB MTHFD1L monoclonal antibody (M01), clone 1E8 Western Blot analysis of MTHFD1L expression in PC-12. 0.1 mg Log in to see 8至11个工作日
$450.00
详细
Bat 山羊 非结合性 IHC (p), ELISA, WB Human Tonsil: Formalin-Fixed, Paraffin-Embedded (FFPE) 50 μg Log in to see 7至9个工作日
$451.00
详细
山羊 非结合性 ELISA, WB ABIN768655 (0.1 µg/mL) staining of Human Cerebellum lysate (35 µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. ABIN768655 (0.1 µg/mL) staining of NIH3T3 (A), Mouse Brain (B) and Rat Brain (C) lysates (35 µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. 100 μg Log in to see 6至7个工作日
$326.89
详细
山羊 非结合性 ELISA, WB Western Blot: MTHFD1L Antibody [NBP1-78279] (0.1ug/ml) staining of Human Cer(35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. 0.1 mg Log in to see 7至9个工作日
$408.19
详细
山羊 非结合性 ELISA, WB 0.1 mg Log in to see 2至3个工作日
$481.25
详细
非结合性 IF, IHC, WB Western blot analysis of extracts of various cells, using MTHFD1L antibody. Immunofluorescence analysis of A549 cell using MTHFD1L antibody. Blue: DAPI for nuclear staining. 100 μL Log in to see 16 Days
$323.13
详细
非结合性 IC, IF, WB Immunofluorescent analysis of MTHFD1L staining in A549 cells. Formalin-fixed cells were permeabilized with 0.1% Triton X-100 in TBS for 5-10 minutes and blocked with 3% BSA-PBS for 30 minutes at room temperature. Cells were probed with the primary antibod Western blot analysis of MTHFD1L expression in HepG2 (A), A549 (B), mouse brain (C), rat heart (D) whole cell lysates. 200 μL Log in to see 13至14个工作日
$487.50
详细
Cow 山羊 非结合性 EIA, WB   0.1 mg Log in to see 12至15个工作日
$375.38
详细
小鼠 非结合性 ELISA, WB MTHFD1L monoclonal antibody (M01), clone 1E8 Western Blot analysis of MTHFD1L expression in PC-12 . Detection limit for recombinant GST tagged MTHFD1L is 0.3 ng/ml as a capture antibody. 100 μg Log in to see 11至12个工作日
$430.00
详细
非结合性 ICC, IF, WB Immunocytochemistry/Immunofluorescence: MTHFD1L Antibody  - Staining of human cell line MCF7 shows localization to mitochondria. Western Blot: MTHFD1L Antibody  - Western blot analysis in human cell line RT-4 and human cell line U-251 MG. 100 μL Log in to see 10至13个工作日
$439.69
详细

通过反应活性、应用领域、克隆类型和共轭标记 MTHFD1L 抗体

特性 应用范围 宿主 克隆类型 标记
Human
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Rat (Rattus)
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Mouse (Murine)
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引用最多的anti-MTHFD1L 抗体

  1. Human Polyclonal MTHFD1L Primary Antibody for ELISA, WB - ABIN4335965 : Parle-McDermott, Pangilinan, OBrien, Mills, Magee, Troendle, Sutton, Scott, Kirke, Molloy, Brody: A common variant in MTHFD1L is associated with neural tube defects and mRNA splicing efficiency. in Human mutation 2009 (PubMed)

更多抗MTHFD1L的相互作用对抗体

Human Methylenetetrahydrofolate Dehydrogenase (NADP+ Dependent) 1-Like (MTHFD1L) interaction partners

  1. study identifies MTHFD1L in the folate cycle as an important metabolic pathway in cancer cells with the potential for therapeutic targeting

  2. Studies reported that the A allele of a polymorphism in a gene involved in folate metabolism, MTHFD1L, showed a genome-wide significant association with late-onset Alzheimer's Disease.

  3. rs6922269 variant at MTHFD1L gene could be an important prognostic factor for cardiovascular mortality in patients after ACS.

  4. MTHFD1L rs6922269 genotype is associated with active vitamin B12 (显示 NDUFB3 抗体) levels at baseline and may be a marker of prognostic risk in patients with established coronary heart disease.

  5. Results indicate that miR (显示 MLXIP 抗体)-9 and MiR (显示 MLXIP 抗体)-197 specifically downregulate MTHFD1L in HEK293 and MCF-7 cells and that SNPrs7646 affects miR (显示 MLXIP 抗体)-197 binding to the MTHFD1L 3' UTR (显示 UTS2R 抗体) causing gene repression in the presence of the allele associated with neural tube defects.

  6. The rs3832406 polymorphism was associated with isolated cleft lip with or without cleft palate.(MTHFD1L)

  7. This study support a role of MTHFD1L gene in late-onset Alzheimer's disease in a Northern Han Chinese population.

  8. No evidence of association between the MTHFD1L marker and susceptibility to Alzheimer's disease is found in a sample from a Spanish population.

  9. Prevalence of minor allele A (adenosine) in rs11754661 single nucleotide polymorphism of MTHFD1L contributes to the risk of Alzheimer's disease in a Han population of mainland China.

  10. mitochondrial C1-tetrahydrofolate synthase (显示 MTHFD1 抗体) gene structure and tissue distribution

Mouse (Murine) Methylenetetrahydrofolate Dehydrogenase (NADP+ Dependent) 1-Like (MTHFD1L) interaction partners

  1. Deletion of Mthfd1l causes embryonic lethality and neural tube and craniofacial defects in mice.

  2. Data show that the MTHFD1L enzyme is present in mitochondria from normal embryonic tissues and embryonic fibroblast cell lines, and embryonic mitochondria possess the ability to synthesize formate from glycine.

MTHFD1L 抗原简介

蛋白简介

The protein encoded by this gene is involved in the synthesis of tetrahydrofolate (THF) in the mitochondrion. THF is important in the de novo synthesis of purines and thymidylate and in the regeneration of methionine from homocysteine. Several transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with MTHFD1L

  • methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1 like (MTHFD1L) 抗体
  • methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like (Mthfd1l) 抗体
  • 2410004L15Rik 抗体
  • AI647056 抗体
  • dJ292B18.2 抗体
  • Fthfsdc1 抗体
  • MTC1THFS 抗体

Protein level used designations for MTHFD1L

10-formyl-THF synthetase , formyltetrahydrofolate synthetase domain containing 1 , monofunctional C1-tetrahydrofolate synthase, mitochondrial , formyltetrahydrofolate synthetase

GENE ID SPECIES
25902 Homo sapiens
361472 Rattus norvegicus
476245 Canis lupus familiaris
534296 Bos taurus
270685 Mus musculus
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