Metastasis Associated in Colon Cancer 1 (MACC1) ELISA试剂盒

MACC1 is a key regulator of the hepatocyte growth factor (HGF\; MIM 142409)-HGF receptor (HGFR, or MET\; MIM 164860) pathway, which is involved in cellular growth, epithelial-mesenchymal transition, angiogenesis, cell motility, invasiveness, and metastasis. 再加上,我们可以发MACC1 抗体 (41)MACC1 蛋白 (4)和数多这个蛋白质的别的产品。

list all ELISA KIts 基因 基因ID UniProt
MACC1 346389 Q6ZN28
小鼠 MACC1 MACC1 238455  
大鼠 MACC1 MACC1 314539  

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产品编号 适用 灵敏度 范围 图像 规格 供应商 交付 价格 详细
0.116 ng/mL 0.31-20 ng/mL 96 Tests Log in to see 7至10个工作日
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引用最多的MACC1 ELISA试剂盒

  1. Human MACC1 ELISA Kit for Sandwich ELISA - ABIN649116 : Wang, Kang, Lu, Chen, Zhang, Wu: MACC1: A potential molecule associated with pancreatic cancer metastasis and chemoresistance. in Oncology letters 2012 (PubMed)
    Show all 2 references for 649116

适于 MACC1 相互作用对的更多 ELISA 试剂盒

Human Metastasis Associated in Colon Cancer 1 (MACC1) interaction partners

  1. MACC1 is a key driver and prognostic biomarker for cancer progression and metastasis in a large variety of solid tumor types, particularly colorectal cancer (CRC (显示 CALR ELISA试剂盒)). Data suggest that some small molecules with antineoplastic activity inhibit MACC1 transcription in CRC (显示 CALR ELISA试剂盒) and prevent liver metastasis in CRC (显示 CALR ELISA试剂盒); lovastatin and rottlerin are the antineoplastic agents used here.

  2. MACC1 regulates Fas (显示 FAS ELISA试剂盒) mediated apoptosis through STAT1 (显示 STAT1 ELISA试剂盒)/3 - Mcl-1 (显示 MCL1 ELISA试剂盒) signaling in solid cancers.

  3. High expression of MACC1 is associated with non-small cell lung cancer.

  4. MACC1 down-regulation suppresses endometrial carcinoma cell proliferation.

  5. SPON2 (显示 SPON2 ELISA试剂盒) is a transcriptional target of the metastasis gene MACC1. SPON2 (显示 SPON2 ELISA试剂盒) induces cell motility in vitro and CRC (显示 CALR ELISA试剂盒) metastasis in mice. In patients, SPON2 (显示 SPON2 ELISA试剂盒) serves as prognostic indicator for CRC (显示 CALR ELISA试剂盒) metastasis and survival, and might represent a promising target for therapeutic approaches.

  6. High MACC1 expression is associated with Angiogenesis and recurrence in Gastric Cancer.

  7. Elevated Orai1 (显示 ORAI1 ELISA试剂盒) and STIM1 (显示 STIM1 ELISA试剂盒) expressions upregulate MACC1 expression to promote tumor cell proliferation, metabolism, migration, and invasion in human gastric cancer.

  8. Data show that metastasis-associated in colon cancer-1 (MACC1) and monocarboxylate transporter 1 (MCT1) are highly expressed in gastric cancer indicating poor prognosis.

  9. A novel role of MACC1 in gastric cancer cell lipogenesis.MACC1 and FASN (显示 FASN ELISA试剂盒) are positively correlated and responsible for the poor prognoses in gastric cancer patients.

  10. MACC1 is more frequently expressed in a poor prognosis phenotype of gastric cancer and acts as a promising prognostic prediction parameter for gastric cancer

Mouse (Murine) Metastasis Associated in Colon Cancer 1 (MACC1) interaction partners

  1. Data suggest a critical role for MACC1 in lymphatic dissemination of GC, providing evidence that MACC1 upregulated VEGF-C/VEGF-D secretion to promote lymphangiogenesis via c-Met signaling.

  2. HGF, MACC1 and C-met genes involve into malignant cervical tumors occurrence, development and prognosis, and might become potential molecular target therapy site of cervical cancer

  3. MACC1 has a role in colorectal cancer and can be used for imaging in xenografts

  4. MACC1 will be useful for the identification of poor prognosis subjects with colorectal cancer and is a promising new target for intervention in metastasis formation.

MACC1 抗原简介

Antigen Summary

MACC1 is a key regulator of the hepatocyte growth factor (HGF\; MIM 142409)-HGF receptor (HGFR, or MET\; MIM 164860) pathway, which is involved in cellular growth, epithelial-mesenchymal transition, angiogenesis, cell motility, invasiveness, and metastasis. Expression of MACC1 in colon cancer (MIM 114500) specimens is an independent prognostic indicator for metastasis formation and metastasis-free survival (Stein et al., 2009

Gene names and symbols associated with MACC1

  • metastasis associated in colon cancer 1 (MACC1) 抗体
  • metastasis associated in colon cancer 1 (Macc1) 抗体
  • 7a5 抗体
  • 4732474O15Rik 抗体
  • Gm267 抗体
  • RGD1309838 抗体
  • SH3BP4L 抗体

Protein level used designations for MACC1

SH3 domain-containing protein 7a5 , metastasis-associated in colon cancer protein 1 , putative binding protein 7a5

GENE ID SPECIES
346389 Homo sapiens
238455 Mus musculus
314539 Rattus norvegicus
521867 Bos taurus
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