anti-Metastasis Associated in Colon Cancer 1 (MACC1) 抗体

MACC1 is a key regulator of the hepatocyte growth factor (HGF\; MIM 142409)-HGF receptor (HGFR, or MET\; MIM 164860) pathway, which is involved in cellular growth, epithelial-mesenchymal transition, angiogenesis, cell motility, invasiveness, and metastasis. 再加上,我们可以发MACC1 试剂盒 (11)MACC1 蛋白 (4)和数多这个蛋白质的别的产品。

列出全部抗体 基因 基因ID UniProt
MACC1 346389 Q6ZN28
MACC1 238455  
MACC1 314539  
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antibodies-online.cn销售最多的anti-MACC1 抗体

Showing 10 out of 43 products:

产品编号 适用 宿主 标记 应用范围 图像 规格 供应商 交付 价格 详细
非结合性 WB Western blot analysis of MACC1 expression in HEK293T (A), H9C2 (B) whole cell lysates. 200 μL Log in to see 13至14个工作日
$487.50
详细
非结合性 IF (p), IHC (p), WB Formalin-fixed and paraffin embedded human stomach tissue labeled with Anti-MACC1Polyclonal Antibody, Unconjugated (ABIN706526) followed by conjugation to the secondary antibody and DAB staining Formalin-fixed and paraffin embedded human gastric carcinoma labeled with Anti-MACC1 Polyclonal Antibody, Unconjugated (ABIN706526) at 1:200 followed by conjugation to the secondary antibody and DAB staining 100 μL Log in to see 3至7个工作日
$307.45
详细
非结合性 EIA, IHC (p), WB   0.1 mg Log in to see 10至12个工作日
$375.38
详细
非结合性 IHC, IHC (p), WB Western Blot: MACC1 Antibody [NBP1-89351] - Lane 1: Marker [kDa] 250, 130, 100, 70, 55, 35, 25, 15, 10.Lane 2: Human cell line A-431 Immunohistochemistry-Paraffin: MACC1 Antibody [NBP1-89351] - Staining of human duodenum shows cytoplasmic positivity in glandular cells. 0.1 mL Log in to see 10至13个工作日
$439.69
详细
非结合性 IHC, IHC (p), SimWes Simple Western: MACC1 Antibody [NBP1-89352] - Simple Western lane view shows a specific band for MACC1 in 0.2 mg/ml of RT-4 lysate. This experiment was performed under reducing conditions using the 12-230 kDa separation system. Immunohistochemistry-Paraffin: MACC1 Antibody [NBP1-89352] - Staining of human endometrium shows strong cytoplasmic positivity in glandular cells. 0.1 mL Log in to see 10至13个工作日
$439.69
详细
非结合性 ELISA, WB 100 μL Log in to see 16 Days
$175.80
详细
Alexa Fluor 594 IF (p)   100 μL Log in to see 14至21个工作日
$417.45
详细
Cy7 IF (p)   100 μL Log in to see 14至21个工作日
$417.45
详细
Cy3 IF (p)   100 μL Log in to see 14至21个工作日
$417.45
详细
Cy5 IF (p)   100 μL Log in to see 14至21个工作日
$417.45
详细

通过反应活性、应用领域、克隆类型和共轭标记 MACC1 抗体

特性 应用范围 宿主 克隆类型 标记
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Mouse (Murine) , ,


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引用最多的anti-MACC1 抗体

  1. Human Polyclonal MACC1 Primary Antibody for IF (p), IHC (p) - ABIN706526 : Sun, Li, Dai, Tan, Zhao, Li, Wang: Silence of MACC1 expression by RNA interference inhibits proliferation, invasion and metastasis, and promotes apoptosis in U251 human malignant glioma cells. in Molecular medicine reports 2015 (PubMed)
    Show all 3 Pubmed References

  2. Human Polyclonal MACC1 Primary Antibody for IHC, IHC (p) - ABIN4332277 : Ge, Meng, Zhou, Zhang, Ding: Positive MACC1 expression correlates with invasive behaviors and postoperative liver metastasis in colon cancer. in International journal of clinical and experimental medicine 2015 (PubMed)
    Show all 2 Pubmed References

  3. Human Polyclonal MACC1 Primary Antibody for IHC, IHC (p) - ABIN4332275 : Hagemann, Fuchs, Monoranu, Herrmann, Smith, Hohmann, Grabiec, Kessler, Dehghani, Löhr, Ernestus, Vince, Stein: Impact of MACC1 on human malignant glioma progression and patients' unfavorable prognosis. in Neuro-oncology 2013 (PubMed)

  4. Human Polyclonal MACC1 Primary Antibody for ELISA, IHC - ABIN5582886 : Liu, Pan, Guo, Wu, Guo, Peng, Wu, Zuo: A new mechanism of trastuzumab resistance in gastric cancer: MACC1 promotes the Warburg effect via activation of the PI3K/AKT signaling pathway. in Journal of hematology & oncology 2016 (PubMed)

更多抗MACC1的相互作用对抗体

Human Metastasis Associated in Colon Cancer 1 (MACC1) interaction partners

  1. Metastasis-associated in colon cancer 1 is expressed at early stages of colorectal oncogenesis within the affected colonic tissue in colorectal cancer patient cohort.

  2. MACC1 is a key driver and prognostic biomarker for cancer progression and metastasis in a large variety of solid tumor types, particularly colorectal cancer (CRC (显示 CALR 抗体)). Data suggest that some small molecules with antineoplastic activity inhibit MACC1 transcription in CRC (显示 CALR 抗体) and prevent liver metastasis in CRC (显示 CALR 抗体); lovastatin and rottlerin are the antineoplastic agents used here.

  3. MACC1 regulates Fas (显示 FAS 抗体) mediated apoptosis through STAT1 (显示 STAT1 抗体)/3 - Mcl-1 (显示 MCL1 抗体) signaling in solid cancers.

  4. High expression of MACC1 is associated with non-small cell lung cancer.

  5. MACC1 down-regulation suppresses endometrial carcinoma cell proliferation.

  6. SPON2 (显示 SPON2 抗体) is a transcriptional target of the metastasis gene MACC1. SPON2 (显示 SPON2 抗体) induces cell motility in vitro and CRC (显示 CALR 抗体) metastasis in mice. In patients, SPON2 (显示 SPON2 抗体) serves as prognostic indicator for CRC (显示 CALR 抗体) metastasis and survival, and might represent a promising target for therapeutic approaches.

  7. High MACC1 expression is associated with Angiogenesis and recurrence in Gastric Cancer.

  8. Elevated Orai1 (显示 ORAI1 抗体) and STIM1 (显示 STIM1 抗体) expressions upregulate MACC1 expression to promote tumor cell proliferation, metabolism, migration, and invasion in human gastric cancer.

  9. Data show that metastasis-associated in colon cancer-1 (MACC1) and monocarboxylate transporter 1 (MCT1) are highly expressed in gastric cancer indicating poor prognosis.

  10. A novel role of MACC1 in gastric cancer cell lipogenesis.MACC1 and FASN (显示 FASN 抗体) are positively correlated and responsible for the poor prognoses in gastric cancer patients.

Mouse (Murine) Metastasis Associated in Colon Cancer 1 (MACC1) interaction partners

  1. Data suggest a critical role for MACC1 in lymphatic dissemination of GC, providing evidence that MACC1 upregulated VEGF-C/VEGF-D secretion to promote lymphangiogenesis via c-Met signaling.

  2. HGF, MACC1 and C-met genes involve into malignant cervical tumors occurrence, development and prognosis, and might become potential molecular target therapy site of cervical cancer

  3. MACC1 has a role in colorectal cancer and can be used for imaging in xenografts

  4. MACC1 will be useful for the identification of poor prognosis subjects with colorectal cancer and is a promising new target for intervention in metastasis formation.

MACC1 抗原简介

蛋白简介

MACC1 is a key regulator of the hepatocyte growth factor (HGF\; MIM 142409)-HGF receptor (HGFR, or MET\; MIM 164860) pathway, which is involved in cellular growth, epithelial-mesenchymal transition, angiogenesis, cell motility, invasiveness, and metastasis. Expression of MACC1 in colon cancer (MIM 114500) specimens is an independent prognostic indicator for metastasis formation and metastasis-free survival (Stein et al., 2009

Gene names and symbols associated with MACC1

  • MACC1, MET transcriptional regulator (MACC1) 抗体
  • metastasis associated in colon cancer 1 (Macc1) 抗体
  • MACC1, MET transcriptional regulator (Macc1) 抗体
  • 7a5 抗体
  • 4732474O15Rik 抗体
  • Gm267 抗体
  • RGD1309838 抗体
  • SH3BP4L 抗体

Protein level used designations for MACC1

SH3 domain-containing protein 7a5 , metastasis-associated in colon cancer protein 1 , putative binding protein 7a5

GENE ID SPECIES
346389 Homo sapiens
238455 Mus musculus
314539 Rattus norvegicus
521867 Bos taurus
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