anti-Metastasis Associated in Colon Cancer 1 (MACC1) 抗体

MACC1 is a key regulator of the hepatocyte growth factor (HGF\; MIM 142409)-HGF receptor (HGFR, or MET\; MIM 164860) pathway, which is involved in cellular growth, epithelial-mesenchymal transition, angiogenesis, cell motility, invasiveness, and metastasis. 再加上,我们可以发MACC1 试剂盒 (10)MACC1 蛋白 (4)和数多这个蛋白质的别的产品。

列出全部抗体 基因 基因ID UniProt
MACC1 346389 Q6ZN28
MACC1 238455  
MACC1 314539  

antibodies-online.cn销售最多的anti-MACC1 抗体

Showing 10 out of 41 products:

产品编号 适用 宿主 标记 应用范围 图像 规格 供应商 交付 价格 详细
非结合性 IF (p), IHC (p), WB Formalin-fixed and paraffin embedded human stomach tissue labeled with Anti-MACC1Polyclonal Antibody, Unconjugated (ABIN706526) followed by conjugation to the secondary antibody and DAB staining Formalin-fixed and paraffin embedded human gastric carcinoma labeled with Anti-MACC1 Polyclonal Antibody, Unconjugated (ABIN706526) at 1:200 followed by conjugation to the secondary antibody and DAB staining 100 μL Log in to see 5至7个工作日
¥2,709.56
详细
非结合性 EIA, IHC (p), WB   0.1 mg Log in to see 28至34个工作日
¥3,065.96
详细
非结合性 IHC, IHC (p), WB Western Blot: MACC1 Antibody [NBP1-89351] - Lane 1: Marker [kDa] 250, 130, 100, 70, 55, 35, 25, 15, 10.Lane 2: Human cell line A-431 Immunohistochemistry-Paraffin: MACC1 Antibody [NBP1-89351] - Staining of human duodenum shows cytoplasmic positivity in glandular cells. 0.1 mL Log in to see 28至35个工作日
¥3,591.24
详细
非结合性 IHC, IHC (p), SimWes Simple Western: MACC1 Antibody [NBP1-89352] - Simple Western lane view shows a specific band for MACC1 in 0.2 mg/ml of RT-4 lysate. This experiment was performed under reducing conditions using the 12-230 kDa separation system. Immunohistochemistry-Paraffin: MACC1 Antibody [NBP1-89352] - Staining of human endometrium shows strong cytoplasmic positivity in glandular cells. 0.1 mL Log in to see 28至35个工作日
¥3,591.24
详细
非结合性 ELISA, WB 100 μL Log in to see 34至38个工作日
¥4,371.67
详细
非结合性 WB Western blot analysis of MACC1 expression in HEK293T (A), H9C2 (B) whole cell lysates. 200 μL Log in to see 7至8个工作日
¥3,941.44
详细
非结合性 EIA, IHC (p), WB Human Small Intestine: Formalin-Fixed, Paraffin-Embedded (FFPE) Western blot analysis of MACC1 in mouse liver tissue lysate with MACC1 antibody at (A) 1 and (B) 2 µg/ml. 50 μg Log in to see 29至35个工作日
¥5,095.23
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FITC IF (p)   100 μL Log in to see 14至17个工作日
¥3,655.30
详细
HRP IHC (p), WB   100 μL Log in to see 14至17个工作日
¥3,655.30
详细
Alexa Fluor 350 IF (p)   100 μL Log in to see 14至17个工作日
¥3,655.30
详细

通过反应活性、应用领域、克隆类型和共轭标记 MACC1 抗体

特性 应用范围 宿主 克隆类型 标记
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引用最多的anti-MACC1 抗体

  1. Human Polyclonal MACC1 Primary Antibody for IF (p), IHC (p) - ABIN706526 : Sun, Li, Dai, Tan, Zhao, Li, Wang: Silence of MACC1 expression by RNA interference inhibits proliferation, invasion and metastasis, and promotes apoptosis in U251 human malignant glioma cells. in Molecular medicine reports 2015 (PubMed)
    Show all 3 references for 706526

  2. Human Polyclonal MACC1 Primary Antibody for IHC, IHC (p) - ABIN4332277 : Ge, Meng, Zhou, Zhang, Ding: Positive MACC1 expression correlates with invasive behaviors and postoperative liver metastasis in colon cancer. in International journal of clinical and experimental medicine 2015 (PubMed)
    Show all 2 references for 4332277

  3. Human Polyclonal MACC1 Primary Antibody for IHC, IHC (p) - ABIN4332275 : Hagemann, Fuchs, Monoranu, Herrmann, Smith, Hohmann, Grabiec, Kessler, Dehghani, Löhr, Ernestus, Vince, Stein: Impact of MACC1 on human malignant glioma progression and patients' unfavorable prognosis. in Neuro-oncology 2013 (PubMed)

更多抗MACC1的相互作用对抗体

Human Metastasis Associated in Colon Cancer 1 (MACC1) interaction partners

  1. MACC1 down-regulation suppresses endometrial carcinoma cell proliferation.

  2. SPON2 (显示 SPON2 抗体) is a transcriptional target of the metastasis gene MACC1. SPON2 (显示 SPON2 抗体) induces cell motility in vitro and CRC (显示 CALR 抗体) metastasis in mice. In patients, SPON2 (显示 SPON2 抗体) serves as prognostic indicator for CRC (显示 CALR 抗体) metastasis and survival, and might represent a promising target for therapeutic approaches.

  3. High MACC1 expression is associated with Angiogenesis and recurrence in Gastric Cancer.

  4. Elevated Orai1 (显示 ORAI1 抗体) and STIM1 (显示 STIM1 抗体) expressions upregulate MACC1 expression to promote tumor cell proliferation, metabolism, migration, and invasion in human gastric cancer.

  5. Data show that metastasis-associated in colon cancer-1 (MACC1) and monocarboxylate transporter 1 (MCT1) are highly expressed in gastric cancer indicating poor prognosis.

  6. A novel role of MACC1 in gastric cancer cell lipogenesis.MACC1 and FASN (显示 FASN 抗体) are positively correlated and responsible for the poor prognoses in gastric cancer patients.

  7. MACC1 is more frequently expressed in a poor prognosis phenotype of gastric cancer and acts as a promising prognostic prediction parameter for gastric cancer

  8. Results indicate that Nav 1.7 promotes GC progression through MACC1-mediated upregulation of NHE1 (显示 SLC9A1 抗体).

  9. MACC1 gene (metastasis-associated in colon cancer 1) is upregulated in cancer stem cells both resistant and sensitive to chemotherapy

  10. MACC1 overexpression is associated with gastric cancer.

Mouse (Murine) Metastasis Associated in Colon Cancer 1 (MACC1) interaction partners

  1. Data suggest a critical role for MACC1 in lymphatic dissemination of GC, providing evidence that MACC1 upregulated VEGF-C/VEGF-D secretion to promote lymphangiogenesis via c-Met signaling.

  2. HGF, MACC1 and C-met genes involve into malignant cervical tumors occurrence, development and prognosis, and might become potential molecular target therapy site of cervical cancer

  3. MACC1 has a role in colorectal cancer and can be used for imaging in xenografts

  4. MACC1 will be useful for the identification of poor prognosis subjects with colorectal cancer and is a promising new target for intervention in metastasis formation.

MACC1 抗原简介

蛋白简介

MACC1 is a key regulator of the hepatocyte growth factor (HGF\; MIM 142409)-HGF receptor (HGFR, or MET\; MIM 164860) pathway, which is involved in cellular growth, epithelial-mesenchymal transition, angiogenesis, cell motility, invasiveness, and metastasis. Expression of MACC1 in colon cancer (MIM 114500) specimens is an independent prognostic indicator for metastasis formation and metastasis-free survival (Stein et al., 2009

Gene names and symbols associated with MACC1

  • metastasis associated in colon cancer 1 (MACC1) 抗体
  • metastasis associated in colon cancer 1 (Macc1) 抗体
  • 7a5 抗体
  • 4732474O15Rik 抗体
  • Gm267 抗体
  • RGD1309838 抗体
  • SH3BP4L 抗体

Protein level used designations for MACC1

SH3 domain-containing protein 7a5 , metastasis-associated in colon cancer protein 1 , putative binding protein 7a5

GENE ID SPECIES
346389 Homo sapiens
238455 Mus musculus
314539 Rattus norvegicus
521867 Bos taurus
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