Mesencephalic Astrocyte-Derived Neurotrophic Factor (MANF) ELISA试剂盒

The protein encoded by MANF is localized in the endoplasmic reticulum (ER) and golgi, and is also secreted. 再加上,我们可以发MANF 抗体 (94)MANF 蛋白 (29)和数多这个蛋白质的别的产品。

list all ELISA KIts 基因 基因ID UniProt
MANF 7873 P55145
MANF 74840  
MANF 315989  

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产品编号 适用 灵敏度 范围 图像 规格 供应商 交付 价格 详细
6.1 pg/mL 15.6-1000 pg/mL 96 Tests Log in to see 7至10个工作日
¥3,480.75
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小鼠 6.2 pg/mL 15.62-1000 pg/mL 96 Tests Log in to see 7至10个工作日
¥3,577.86
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大鼠 0.078 ng/mL 0.312-20 ng/mL Typical standard curve 96 Tests Log in to see 7至10个工作日
¥6,624.10
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Pig 9.375 pg/mL 15.625-1000 pg/mL   96 Tests Log in to see 6至8个工作日
¥5,717.40
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小鸡 0.469 pg/mL 0.781-50 pg/mL   96 Tests Log in to see 6至8个工作日
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0.375 pg/mL 0.625-40 pg/mL   96 Tests Log in to see 6至8个工作日
¥5,717.40
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豚鼠 0.469 pg/mL 0.781-50 pg/mL   96 Tests Log in to see 6至8个工作日
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大鼠 31.2-2000 pg/mL   96 Tests Log in to see 24至29个工作日
¥7,088.76
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9.375 pg/mL 15.625-1000 pg/mL   96 Tests Log in to see 6至8个工作日
¥5,717.40
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  96 Tests Log in to see 29至34个工作日
¥7,958.62
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引用最多的MANF ELISA试剂盒

  1. Human MANF ELISA Kit for Sandwich ELISA - ABIN418010 : Larráyoz, de Luis, Rúa, Velilla, Cabello, Martínez: Molecular effects of doxycycline treatment on pterygium as revealed by massive transcriptome sequencing. in PLoS ONE 2012 (PubMed)
    Show all 3 Pubmed References

适于 MANF 相互作用对的更多 ELISA 试剂盒

Fruit Fly (Drosophila melanogaster) Mesencephalic Astrocyte-Derived Neurotrophic Factor (MANF) interaction partners

  1. Study employed the Drosophila genetics to screen for potential interaction partners of Drosophila Manf (DmManf) in vivo; show that DmManf plays a role in the development of Drosophila wing.

  2. These data suggest a role for Manf in the regulation of Drosophila unfolded protein response.

  3. DmMANF expression in the adult brain is much wider than in the embryonic and larval stages. It is expressed in both glia and neurons including dopaminergic neurons.

  4. study offers further insights into the functional conservation between invertebrate and mammalian MANF/CDNF (显示 CDNF ELISA试剂盒) proteins and reveals the importance of the C-terminal domain for MANF activity in vivo

  5. role of MANF in multicellular organism development

  6. DmMANF is an invertebrate neurotrophic factor (显示 NTF3 ELISA试剂盒) supporting dopaminergic neurons.

Zebrafish Mesencephalic Astrocyte-Derived Neurotrophic Factor (MANF) interaction partners

  1. These results suggest that MANF is involved in the regulation of the development of dopaminergic system in zebrafish.

Human Mesencephalic Astrocyte-Derived Neurotrophic Factor (MANF) interaction partners

  1. the role of two short sequence motifs within the carboxy-(C) terminal domain of MANF in its neuroprotective activity, was studied.

  2. the selective expression of MANF in splenocytes may be involved in plasma cell differentiation and immune regulation.

  3. MANF is a protein that interacts with RTN1-C (显示 RTN1 ELISA试剂盒)

  4. We demonstrate that Armet and Creld2 (显示 CRELD2 ELISA试剂盒) are genotype-specific ER stress response proteins with substrate specificities, and that aggregation of mutant matrilin-3 (显示 MATN3 ELISA试剂盒) is a key disease trigger in MED that could be exploited as a potential therapeutic target

  5. MANF binding to the plasma membrane also required the RTDL sequence and was inhibited with a peptide known to interact with KDELRs, suggesting MANF binds KDELRs at the surface.

  6. MANF and C-MANF protect neurons intracellularly as efficiently as Ku70.

  7. Pretreatment with adeno (显示 ADORA2A ELISA试剂盒)-associated-virus vector containing human MANF reduces the volume of cerebral infarction and facilitates behavioral recovery in experimental stroke rats.

  8. Armet is a novel secreted mediator of the adaptive pathway of unfolded protein response.

  9. The widespread expression of MANF together with its evolutionary conserved nature and regulation by brain insults suggest that it has important functions both under normal and pathological conditions in many tissue types.

  10. structures of MANF and CDNF (显示 CDNF ELISA试剂盒) were solved; structure explains why MANF and CDNF (显示 CDNF ELISA试剂盒) are bifunctional; neurotrophic activity may reside in the N-terminal domain and ER stress response in the C-terminal domain

Mouse (Murine) Mesencephalic Astrocyte-Derived Neurotrophic Factor (MANF) interaction partners

  1. MANF decreased the proinflammatory cytokines of IL-1beta (显示 IL1B ELISA试剂盒), TNF-alpha (显示 TNF ELISA试剂盒), and IFN-gamma induced (显示 SAMHD1 ELISA试剂盒) by LPS (显示 TLR4 ELISA试剂盒) by regulating NF-kappaB (显示 NFKB1 ELISA试剂盒) and phosphorylation of p38 (显示 CRK ELISA试剂盒)-mitogen-activated protein kinases (MAPKs) pathways

  2. MANF has immune modulatory properties that are required for retinal repair in Drosophila

  3. secretion of mouse MANF and mouse CDNF (显示 CDNF ELISA试剂盒) is fundamentally regulated in the same manner, the variation of four C-terminal amino acids in the MANF and CDNF (显示 CDNF ELISA试剂盒) among species might influence their intracellular functions.

  4. MANF-deficient mice develop severe diabetes, progressive postnatal reduction of beta cell mass and chronic unfolded protein response activation.

  5. Secretion of MANF is regulated via COPII-mediated transport and that its C-terminus could be responsible for its retention in the endoplasmic reticulum through GRP78 (显示 HSPA5 ELISA试剂盒).

  6. The change in Armet expression lasted while the change of Mrpl51 (显示 MRPL51 ELISA试剂盒) disappeared after birth.

  7. the solution structure of ARMET

  8. ARMET is the second fully characterized ERSE-II-dependent gene and likely contributes to quality control of proteins in the endoplasmic reticulum

  9. The widespread expression of MANF together with its evolutionary conserved nature and regulation by brain insults suggest that it has important functions both under normal and pathological conditions in many tissue types.

MANF 抗原简介

Antigen Summary

The protein encoded by this gene is localized in the endoplasmic reticulum (ER) and golgi, and is also secreted. Reducing expression of this gene increases susceptibility to ER stress-induced death and promotes cell proliferation. The protein was initially thought to be longer at the N-terminus and to contain an arginine-rich region but transcribed evidence indicates a smaller open reading frame that does not encode the arginine tract. The presence of polymorphisms in the arginine-rich region, including a specific mutation that changes the previously numbered codon 50 from ATG to AGG, have been reported in a variety of solid tumors\; however, these polymorphisms were later shown to exist in normal tissues and are thus not tumor-related.

Gene names and symbols associated with MANF

  • mesencephalic astrocyte-derived neurotrophic factor (MANF) 抗体
  • Mesencephalic astrocyte-derived neurotrophic factor (Manf) 抗体
  • mesencephalic astrocyte-derived neurotrophic factor (manf) 抗体
  • mesencephalic astrocyte-derived neurotrophic factor (Manf) 抗体
  • 3230402M22Rik 抗体
  • AA407711 抗体
  • AA408789 抗体
  • AA673178 抗体
  • anon-EST:ParkEST188 抗体
  • Armet 抗体
  • ARP 抗体
  • ARP-like 抗体
  • CG7013 抗体
  • D18Mgi17 抗体
  • D17914 抗体
  • Dmel\\CG7013 抗体
  • DmMANF 抗体
  • im:6909481 抗体
  • MANF 抗体
  • RBM15B 抗体
  • zgc:153327 抗体

Protein level used designations for MANF

mesencephalic astrocyte-derived neurotrophic factor , arginine-rich, mutated in early stage tumors , CG7013-PA , Manf-PA , ARP-like , arginine-rich protein , RNA binding motif protein 15B , chromosome 3p21.1 gene sequence

GENE ID SPECIES
745542 Pan troglodytes
41983 Drosophila melanogaster
549179 Xenopus (Silurana) tropicalis
767691 Danio rerio
7873 Homo sapiens
608421 Canis lupus familiaris
74840 Mus musculus
315989 Rattus norvegicus
540432 Bos taurus
100505460 Sus scrofa
770664 Gallus gallus
100719906 Cavia porcellus
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