Matrix Metallopeptidase 13 (Collagenase 3) (MMP13) ELISA试剂盒

Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as art. 再加上,我们可以发Matrix Metallopeptidase 13 (Collagenase 3) 抗体 (287)Matrix Metallopeptidase 13 (Collagenase 3) 蛋白 (49)和数多这个蛋白质的别的产品。

list all ELISA KIts 基因 基因ID UniProt
MMP13 17386 P33435
MMP13 171052  
MMP13 4322 P45452

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产品编号 适用 灵敏度 范围 图像 规格 供应商 交付 价格 详细
0.113 ng/mL 0.31-20 ng/mL 96 Tests Log in to see 7至10个工作日
¥3,140.87
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小鼠 28 pg/mL 78-5000 pg/mL 96 Tests Log in to see 7至10个工作日
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大鼠 0.063 ng/mL 0.15-10 ng/mL 96 Tests Log in to see 7至10个工作日
¥3,403.06
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23.44 pg/mL 93.75-6000 pg/mL Typical standard curve 96 Tests Log in to see 7至10个工作日
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Cow 33 pg/mL 78.125-5000 pg/mL 96 Tests Log in to see 9至11个工作日
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小鸡 0.63 ng/mL 1.56-100 ng/mL 96 Tests Log in to see 9至11个工作日
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6.9 pg/mL 15.625-1000 pg/mL 96 Tests Log in to see 9至11个工作日
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Pig 0.113 ng/mL 0.312-20 ng/mL 96 Tests Log in to see 9至11个工作日
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山羊 1.25 ng/mL 3.125-200 ng/mL 96 Tests Log in to see 9至11个工作日
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0.039 ng/mL 0.156-10 ng/mL   96 Tests Log in to see 24至29个工作日
¥4,987.13
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引用最多的Matrix Metallopeptidase 13 (Collagenase 3) ELISA试剂盒

  1. Mouse (Murine) MMP13 ELISA Kit for Sandwich ELISA - ABIN415612 : Campo, Avenoso, Nastasi, Micali, Prestipino, Vaccaro, DAscola, Calatroni, Campo: Hyaluronan reduces inflammation in experimental arthritis by modulating TLR-2 and TLR-4 cartilage expression. in Biochimica et biophysica acta 2011 (PubMed)
    Show all 10 references for 415612

  2. Human MMP13 ELISA Kit for Sandwich ELISA - ABIN414818 : Mern, Fontana, Beierfuß, Thomé, Hegewald et al.: A combinatorial relative mass value evaluation of endogenous bioactive proteins in three-dimensional cultured nucleus pulposus cells of herniated intervertebral discs: identification of potential ... in PLoS ONE 2013 (PubMed)
    Show all 4 references for 414818

  3. Rabbit MMP13 ELISA Kit for Sandwich ELISA - ABIN577622 : Aydin, Korkusuz, Korkusuz, Tezcaner, Bilgic, Yaprakci, Keskin: In vitro and in vivo evaluation of doxycycline-chondroitin sulfate/PCLmicrospheres for intraarticular treatment of osteoarthritis. in Journal of biomedical materials research. Part B, Applied biomaterials 2014 (PubMed)
    Show all 2 references for 577622

  4. Rat (Rattus) MMP13 ELISA Kit for Sandwich ELISA - ABIN416348 : Morsy, Abdalla, Mahmoud, Abdelwahab, Mahmoud: Protective effects of curcumin, ?-lipoic acid, and N-acetylcysteine against carbon tetrachloride-induced liver fibrosis in rats. in Journal of physiology and biochemistry 2012 (PubMed)
    Show all 2 references for 416348

适于 Matrix Metallopeptidase 13 (Collagenase 3) 相互作用对的更多 ELISA 试剂盒

Zebrafish Matrix Metallopeptidase 13 (Collagenase 3) (MMP13) interaction partners

  1. MeHg impairs tail development at least partially by activation of the tissue remodeling proteases Mmp9 (显示 MMP9 ELISA试剂盒) and Mmp13.

  2. Zebra fish embryogenesis requires MMP-13 and dexamethasone and hydrocortisone modulate the expression of this gene, leading to increased activity and potentially contributing to subsequent dysmorphogenesis.

  3. JNK (显示 MAPK8 ELISA试剂盒)-Mmp13 signaling pathway plays an essential role in regulating the innate immune cell migration in response to severe injury in vivo

Xenopus laevis Matrix Metallopeptidase 13 (Collagenase 3) (MMP13) interaction partners

  1. XCL3 and XCL4 can be differentially induced by prolactin (显示 PRL ELISA试剂盒) and thyroid hormone (显示 PTH ELISA试剂盒)(3)

Mouse (Murine) Matrix Metallopeptidase 13 (Collagenase 3) (MMP13) interaction partners

  1. The progressive process of articular cartilage degeneration was significantly delayed in the knee joints of Ddr2 (显示 DDR2 ELISA试剂盒)-deficient mice in comparison to their control littermates. Articular cartilage damage in the knee joints of the mice was associated with increased expression profiles of both Ddr2 (显示 DDR2 ELISA试剂盒) and matrix metalloproteinase 13.

  2. Postnatal chondrocyte-specific deletion of Hdac3 (显示 HDAC3 ELISA试剂盒) with an inducible Col2a1 (显示 COL2A1 ELISA试剂盒)-Cre caused premature production of pErk1/2 and Mmp13 in the growth plate.

  3. Mmp13 is selectively regulated of by 1,25-Dihydroxyvitamin D3, PTH (显示 PTH ELISA试剂盒), and Osterix (显示 SP7 ELISA试剂盒) through distal enhancers.

  4. Our study contributes to the understanding of the role of HIF1alpha (显示 HIF1A ELISA试剂盒) in OA and highlights the HIF1alpha (显示 HIF1A ELISA试剂盒)-beta-catenin (显示 CTNNB1 ELISA试剂盒) interaction, thus providing new insights into the impact of hypoxia in articular cartilage.

  5. Matrix metalloproteinases (MMP) are effectors of hippocampal neuroplasticity in the adult central nervous system and that the MMP-1 (显示 MMP1 ELISA试剂盒)/protease-activated receptor-1 (显示 F2R ELISA试剂盒) axis may play a role in neurogenesis following physiological and/or pathological stimuli.

  6. IL-1Ra (显示 IL1RN ELISA试剂盒) is associated with MMP-13 expression and has a novel function in such regulation without interference of the IL-1 (显示 IL1A ELISA试剂盒) signaling cascade.

  7. We reveal a novel role of AP-2epsilon in the regulation of gene expression in articular chondrocytes, as well as in osteoarthritis development, through modulation of Mmp13 expression and activity.

  8. B-16 melanoma cells with up-regulated MMP-13 expression promoted invasion of tumor cells through Matrigel compared with control cells transfected with empty vector. Knocked-down MMP-13 expression also decreased invading cell numbers.

  9. MMP-12 (显示 MMP12 ELISA试剂盒) and MMP-13 alter strain K infection in mice and play a role in inflammatory regulation by modulating cytokine levels.

  10. Data indicate that tamoxifen decreased collage type II COL2A1 (显示 COL2A1 ELISA试剂盒) by activating matrix metallopeptidases MMP-2 (显示 MMP2 ELISA试剂盒)/13 expression.

Human Matrix Metallopeptidase 13 (Collagenase 3) (MMP13) interaction partners

  1. High MMP13 expression is associated with intervertebral disc degeneration.

  2. data demonstrate that MMP-13 is critical for the development of osteolytic lesions in Multiple myeloma and that targeting the MMP-13 protein - rather than its catalytic activity - constitutes a potential approach to mitigating bone disease in affected patients.

  3. Endoplasmic reticulum stress participates in the progress of senescence and apoptosis of osteoarthritic chondrocytes, which manifested in increased expression of ADAMTS5 (显示 ADAMTS5 ELISA试剂盒), MMP13, and decreased COL2A1 (显示 COL2A1 ELISA试剂盒) expression.

  4. Matrix metalloprotease (显示 ADAM8 ELISA试剂盒) (MMP) regulation was the top pathway involved in gingival aging. MMP3 (显示 MMP3 ELISA试剂盒), MMP9 (显示 MMP9 ELISA试剂盒), MMP12 (显示 MMP12 ELISA试剂盒), and MMP13 were upregulated in old gingival tissues, concomitantly with interleukin-1 beta (IL1B (显示 IL1B ELISA试剂盒)) expression.

  5. these findings support roles for both cFOS (indirect) and ATF3 (显示 ATF3 ELISA试剂盒) (direct) in effecting MMP13 transcription in human chondrocytes.

  6. Oxytocin prevents cartilage matrix destruction via regulating MMP1 (显示 MMP1 ELISA试剂盒) and MMP13.

  7. These studies have uncovered a new, ATP6V1H (显示 ATP6V1H ELISA试剂盒)-mediated pathway that regulates bone formation, and defines a new mechanism of disease that leads to bone loss. We propose that MMP9 (显示 MMP9 ELISA试剂盒)/MMP13 could be therapeutic targets for patients with this rare genetic disease.

  8. To conclude, Pseudomonas aeruginosa infection induced the expression of matrix metalloproteinases, and Pseudomonas aeruginosa type III secretion system appeared to be a key player in MMP-12 (显示 MMP12 ELISA试剂盒) and MMP-13 expression, which is further controlled by NF-kappaB (显示 NFKB1 ELISA试剂盒) signaling.

  9. In osteoarthritis (OA) chondrocytes, hydrostatic pressure (HP) restores the expression levels of some miRNAs, downregulates MMP-13, ADAMTS-5 (显示 ADAMTS5 ELISA试剂盒), and HDAC-4 (显示 HDAC4 ELISA试剂盒), and modulates the Wnt (显示 WNT2 ELISA试剂盒)/beta-catenin (显示 CTNNB1 ELISA试剂盒) pathway activation.

  10. These results suggested that HIF-2alpha (显示 EPAS1 ELISA试剂盒) may cause meniscal matrix degradation by transactivation of MMP-13

Horse (Equine) Matrix Metallopeptidase 13 (Collagenase 3) (MMP13) interaction partners

  1. The DNA microarray analysis for matrix metalloproteinase (显示 MMP20 PLURAL_@17599@) (MMP)-related mRNA expression in equine superficial digital flexor tendinitis indicated that mRNA level of MMP-13 was apparently up-regulated in the tendinitis as compared to normal tendon.

Cow (Bovine) Matrix Metallopeptidase 13 (Collagenase 3) (MMP13) interaction partners

  1. p38 (显示 MAPK14 ELISA试剂盒) phosphorylation and MMP13 expression are regulated by Rho/ROCK activation, and support the potential novel pathway that Rho/ROCK is in the upper part of the mechanical stress-induced matrix degeneration cascade in cartilage.

  2. These data identify atypical PKC isozymes as STAT and ERK activators that mediate c-fos and collagenase expression.

  3. MMP-13 treatment of fresh articular cartilage results in cleaved fibromodulin (显示 FMOD ELISA试剂盒) fragments

  4. increased in bovine preovulatory follicles following the gonadotropin surge but no up-regulation of MMP-1 (显示 MMP1 ELISA试剂盒) and MMP-13 (follicular apex (显示 APEX1 ELISA试剂盒) vs. base) for the preovulatory collagenolysis required for follicle rupture

  5. involvement of p38 MAP kinase (显示 MAPK14 ELISA试剂盒) in the hyaluronan oligosaccharide induction of MMP-13

  6. MMP-13 and collagenase have roles in chondrocyte hypertrophy induced by type II collagen (显示 COL2A1 ELISA试剂盒)

  7. At high but naturally occurring concentrations the collagen peptide CB12 (显示 PABPC4 ELISA试剂盒)-II induced an increase in the expressions of MMP-13 and cleavage of type II collagen (显示 COL2A1 ELISA试剂盒) by collagenase in the mid zone and also in the superficial zone.

Rabbit Matrix Metallopeptidase 13 (Collagenase 3) (MMP13) interaction partners

  1. These results suggest that PEP-1-SIRT2 (显示 SIRT2 ELISA试剂盒) promotes matrix metalloproteinases-induced dedifferentiation via ERK (显示 MAPK1 ELISA试剂盒) signaling in articular chondrocytes.

  2. chitosan-pDNA nanoparticles encoding shRNA targeting MMP-3 (显示 MMP3 ELISA试剂盒) and -13 had great potential in silencing the dedifferentiation-related genes for regenerating prolonged and endurable cartilage.

  3. Leptin (显示 LEP ELISA试剂盒) can induce MMP-13 and have a synergistic induction effect on NO with TNF-alpha (显示 TNF ELISA试剂盒) in rabbit articular chondrocytes in vitro.

Pig (Porcine) Matrix Metallopeptidase 13 (Collagenase 3) (MMP13) interaction partners

  1. TNF-alpha (显示 TNF ELISA试剂盒) induced MMP-13 expression by condylar cells might be involved in the degradation of the juvenile condyle.

Matrix Metallopeptidase 13 (Collagenase 3) (MMP13) 抗原简介

Antigen Summary

Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. The protein encoded by this gene cleaves type II collagen more efficiently than types I and III. It may be involved in articular cartilage turnover and cartilage pathophysiology associated with osteoarthritis. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3.

Gene names and symbols associated with MMP13

  • matrix metalloproteinase 13a (mmp13a) 抗体
  • matrix metalloproteinase 13 (MGC68994) 抗体
  • matrix metallopeptidase 13 (collagenase 3) (MMP13) 抗体
  • matrix metallopeptidase 13 (collagenase 3) (mmp13) 抗体
  • matrix metalloproteinase 13 (LOC100136348) 抗体
  • matrix metalloproteinase 13 (mmp13) 抗体
  • collagenase 3 (MMP-13) 抗体
  • matrix metallopeptidase 13 (Mmp13) 抗体
  • matrix metalloproteinase 13 precursor (MMP-13) 抗体
  • cb1034 抗体
  • Clg 抗体
  • CLG3 抗体
  • gene A 抗体
  • MANDP1 抗体
  • MGC108008 抗体
  • MMP-13 抗体
  • Mmp1 抗体
  • MMP13 抗体
  • xcl3 抗体
  • xCol 抗体

Protein level used designations for MMP13

matrix metalloproteinase 13 , MMPLg , MMPLh , matrix metallopeptidase 13 (collagenase 3) , collagenase 3 , gene A , gene 11 , collagenase-3 , collagenase 3-like , Collagenase-3 , collagenase-1 , interstitial collagenase , matrix metalloproteinase-13 , MMP-13 , UMRCASE , matrix metalloproteinase 13 (collagenase 3)

GENE ID SPECIES
387293 Danio rerio
379552 Xenopus laevis
451513 Pan troglodytes
493679 Felis catus
613098 Xenopus (Silurana) tropicalis
703980 Macaca mulatta
772008 Gallus gallus
100012553 Monodelphis domestica
100136348 Salmo salar
100396943 Callithrix jacchus
100462632 Pongo abelii
100526826 Ictalurus punctatus
100552256 Anolis carolinensis
100584961 Nomascus leucogenys
397823 Xenopus laevis
17386 Mus musculus
171052 Rattus norvegicus
4322 Homo sapiens
100009711 Equus caballus
281914 Bos taurus
100008685 Oryctolagus cuniculus
398056 Xenopus laevis
395683 Gallus gallus
403763 Canis lupus familiaris
443113 Ovis aries
397346 Sus scrofa
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