anti-Mannosidase, Alpha, Class 2B, Member 1 (MAN2B1) 抗体

MAN2B1 encodes an enzyme that hydrolyzes terminal, non-reducing alpha-D-mannose residues in alpha-D-mannosides. 再加上,我们可以发Mannosidase, Alpha, Class 2B, Member 1 蛋白 (10)Mannosidase, Alpha, Class 2B, Member 1 试剂盒 (7)和数多这个蛋白质的别的产品。

列出全部抗体 基因 基因ID UniProt
MAN2B1 17159 O09159
大鼠 MAN2B1 MAN2B1 361378  
MAN2B1 4125 O00754
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Showing 10 out of 11 products:

产品编号 适用 宿主 标记 应用范围 图像 规格 供应商 交付 价格 详细
小鼠 非结合性 WB Western blot analysis of extracts of mouse liver cells, using MAN2B1 antibody. 100 μL Log in to see 16 Days
$323.13
详细
非结合性 IHC, IHC (p) Immunohistochemistry: MAN2B1 Antibody [NBP1-81326] - Staining of human small intestine shows strong granular cytoplasmic positivity in glandular cells. 0.1 mL Log in to see 10至13个工作日
$439.69
详细
非结合性 WB Western Blot analysis of MAN2B1 expression in transfected 293T cell line by MAN2B1 MaxPab polyclonal antibody.<br><br>Lane 1: MAN2B1 transfected lysate(113.70 KDa).<br>Lane 2: Non-transfected lysate.<br> MAN2B1 MaxPab rabbit polyclonal antibody. Western Blot analysis of MAN2B1 expression in HepG2. 100 μg Log in to see 11至12个工作日
$418.57
详细
小鼠 非结合性 WB Western Blot analysis of MAN2B1 expression in transfected 293T cell line by MAN2B1 MaxPab polyclonal antibody.<br><br>Lane 1: MAN2B1 transfected lysate(111.21 KDa).<br>Lane 2: Non-transfected lysate.<br> 50 μg Log in to see 11至12个工作日
$430.00
详细
小鼠 非结合性 WB   50 μg Log in to see 7至9个工作日
$837.83
详细
非结合性 WB   100 μg Log in to see 7至9个工作日
$903.83
详细
非结合性 ICC, IHC, IP, WB   100 μg Log in to see 13至16个工作日
$350.00
详细
小鼠 非结合性 WB   50 μg Log in to see 11至16个工作日
$625.43
详细
非结合性 WB   100 μg Log in to see 11至16个工作日
$666.29
详细
非结合性 ELISA, IF/ICC, IHC, WB   100 μg Log in to see 71 Days
$536.25
详细

通过反应活性、应用领域、克隆类型和共轭标记 MAN2B1 抗体

特性 应用范围 宿主 克隆类型
Mouse (Murine)


Human ,
,

更多抗Mannosidase, Alpha, Class 2B, Member 1的相互作用对抗体

Mouse (Murine) Mannosidase, Alpha, Class 2B, Member 1 (MAN2B1) interaction partners

  1. Mannose receptor (-/-) liver sinusoidal endothelial cells had markedly and significantly reduced enzyme activities for four out of five lysosomal enzymes tested, i.e., cathepsin-D, alpha-mannosidase, beta-hexosaminidase and arylsulfatase.

Human Mannosidase, Alpha, Class 2B, Member 1 (MAN2B1) interaction partners

  1. A novel heterozygous mutation (c.2013G>A; p.R638H) of MANBA (显示 MANBA 抗体) was identified in patients with autosomal-dominant nystagmus. An additional mutation (c.2346T>A; p.L749H) in MANBA (显示 MANBA 抗体) was found by screening patients with sporadic nystagmus.

  2. Our results indicate a correlation between the MAN2B1 genotypes and the cognitive function, upper limb coordination, balance, FVC% and the storage of oligosaccharides in CSF (显示 CSF2 抗体).

  3. The results showed that the alpha-mannosidosis patient has compound heterozygous mutations in the MAN2B1 gene

  4. MAN2B1 is targeted to the vacuole without passing through the Golgi complex.

  5. Expressed MAN2B1 and MAN2B2 (显示 MAN2B2 抗体) in Drosophila S2 cells and functionally characterized them. MAN2B1 and MAN2B2 (显示 MAN2B2 抗体) were significantly inhibited by the class II alpha-mannosidase inhibitors, swainsonine and mannostatin A.

  6. 5 new mutations were found in the MAN2B1 gene: c.157G>T, c.562C>T, c.599A>T, c.293dupA, c.2402G>A (p.E53X, p.R188X, p.H200L, p.Y99VfsX61, p.G801D). p.H200L could involve the catalytic mechanism. p.G801D would affect correct folding.

Cow (Bovine) Mannosidase, Alpha, Class 2B, Member 1 (MAN2B1) interaction partners

Mannosidase, Alpha, Class 2B, Member 1 (MAN2B1) 抗原简介

蛋白简介

This gene encodes an enzyme that hydrolyzes terminal, non-reducing alpha-D-mannose residues in alpha-D-mannosides. Its activity is necessary for the catabolism of N-linked carbohydrates released during glycoprotein turnover and it is member of family 38 of glycosyl hydrolases. The full length protein is processed in two steps. First, a 49 aa leader sequence is cleaved off and the remainder of the protein is processed into 3 peptides of 70 kDa, 42 kDa (D) and 13/15 kDa (E). Next, the 70 kDa peptide is further processed into three peptides (A, B and C). The A, B and C peptides are disulfide-linked. Defects in this gene have been associated with lysosomal alpha-mannosidosis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with MAN2B1

  • mannosidase alpha class 2B member 1 (MAN2B1) 抗体
  • mannosidase, alpha, class 2B, member 1 (man2b1) 抗体
  • mannosidase 2, alpha B1 (Man2b1) 抗体
  • mannosidase alpha class 2B member 1 (Man2b1) 抗体
  • mannosidase, alpha, class 2B, member 1 (Man2b1) 抗体
  • AW107687 抗体
  • Laman 抗体
  • MANB 抗体

Protein level used designations for MAN2B1

mannosidase, alpha, class 2B, member 1 , lysosomal alpha-mannosidase (109.3 kD) (XF355) , lysosomal alpha-mannosidase , lysosomal alpha-mannosidase-like , lysosomal acid alpha-mannosidase , mannosidase alpha class 2B member 1 , mannosidase alpha-B , mannosidase 2, alpha B1 , mannosidase, alpha B, lysosomal , laman

GENE ID SPECIES
484932 Canis lupus familiaris
779924 Xenopus (Silurana) tropicalis
100010377 Monodelphis domestica
100174476 Pongo abelii
100395073 Callithrix jacchus
100598622 Nomascus leucogenys
17159 Mus musculus
100718205 Cavia porcellus
361378 Rattus norvegicus
4125 Homo sapiens
282272 Bos taurus
493697 Felis catus
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