Malignant T Cell Amplified Sequence 1 蛋白 (MCTS1)

The protein encoded by MCTS1 is a proton-linked monocarboxylate transporter that catalyzes the movement of many monocarboxylates, such as lactate and pyruvate, across the plasma membrane. 再加上,我们可以发Malignant T Cell Amplified Sequence 1 抗体 (85)Malignant T Cell Amplified Sequence 1 试剂盒 (9)和数多这个蛋白质的别的产品。

列出全部蛋白 基因 基因ID UniProt
MCTS1 17236  
MCTS1 28985 Q9ULC4
MCTS1 302500 Q4G009

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MCTS1 蛋白 by Origin and Source

Origin 在表达 标记
Mouse (Murine)

Human , ,
, , ,
Rat (Rattus)

引用最多的Malignant T Cell Amplified Sequence 1 蛋白

  1. Human MCTS1 Protein expressed in Escherichia coli (E. coli) - ABIN1098561 : Herbert, Shi, Gartenhaus: Expression and stabilization of the MCT-1 protein by DNA damaging agents. in Oncogene 2001 (PubMed)
    Show all 2 references for 1098561

更多Malignant T Cell Amplified Sequence 1 (MCTS1)互动伙伴

Mouse (Murine) Malignant T Cell Amplified Sequence 1 (MCTS1) interaction partners

  1. It was concluded that both MCT1 and CAII (显示 CA2 蛋白) are involved in the homeostatic control of pH in skeletal muscle, both at rest and at the onset of exercise. The improved muscle function and resistance to fatigue in MCT1(+/-) mice remain unexplained.

  2. MCT1 inhibition impairs proliferation of glycolytic breast cancer cells co-expressing MCT1 and MCT4 (显示 SLC16A3 蛋白) via disruption of pyruvate rather than lactate export.

  3. This study demonstrated that MCT1 was up regulation in ipsilateral site of brain afeter cerebral ischemia.

  4. The soleus, liver and heart were the main tissues that showed improved the MCT1 mRNA expression, indicating its important role in controlling MLSS concentration in mice.

  5. Exercise-induced changes in tumour LDH-B (显示 LDHB 蛋白) and MCT1 expression are modulated by oestrogen-related receptor alpha in breast cancer-bearing BALB/c mice

  6. Chronic lactate administration after exercise increases MCT1 protein expression, which can be involved in the regulation of the observed increase in muscle glycogen (显示 GYS1 蛋白) storage after exercise training.

  7. This study showed that mouse MCT1, MCT2, and MCT4 (显示 SLC16A3 蛋白) are expressed in the PNS. While DRG neurons express MCT1, myelinating Schwann cells.

  8. These data for the first time demonstrate that MCT1 is critical for regeneration of both sensory and motor axons in mice following sciatic nerve crush

  9. Study demonstrated that PTEN loss and MCT-1 induction synergistically promoted the neoplastic multinucleation via the Src/p190B signaling activation.

  10. in Parkinson's disease, the levels of MCT1, MCT2 and GLUT1 (显示 SLC2A1 蛋白) is not changed following dopaminergic neurodegeneration

Human Malignant T Cell Amplified Sequence 1 (MCTS1) interaction partners

  1. Data show that metastasis-associated in colon cancer-1 (MACC1 (显示 MACC1 蛋白)) and monocarboxylate transporter 1 (MCT1) are highly expressed in gastric cancer indicating poor prognosis.

  2. AA genotype of the MCT1 (显示 CMA1 蛋白) T1470A polymorphism is over-represented in wrestlers compared with controls and is associated with lower blood lactate concentrations after 30-s Wingate Anaerobic test and during intermittent sprint tests in Japanese wrestlers

  3. MCT1 (显示 CMA1 蛋白) and MCT4 (显示 SLC16A4 蛋白) expression levels were associated with worse prognosis and shorter overall survival.

  4. MCT1 (显示 CMA1 蛋白) may be acting as an uptake transporter and MCT4 (显示 SLC16A4 蛋白) as an efflux system across the basolateral membrane for ferulic acid, and that this process is stimulated by butyric acid.

  5. After indirect co-culture, OP was increased in the BxPc-3 and Panc-1 cells; correspondingly, succinate dehydrogenase (显示 SDHA 蛋白), FH and MCT (显示 MCAT 蛋白) expression were increased. After the MCT1 (显示 CMA1 蛋白)-specific inhibitor removed 'tumor-stromal' metabolic coupling, the migration and invasion abilities of the pancreatic cancer cells were decreased.

  6. Data suggest that inhibition of mnocarboxylate transporters MCT1 (显示 CMA1 蛋白) and MCT4 (显示 SLC16A4 蛋白) may have clinical relevance in pancreatic ductal adenocarcinoma (PDAC).

  7. Results found that MCT (显示 MCAT 蛋白) contributes to endothelial cell growth and tube formation via up-regulation of angiopoietin-1 (显示 ANGPT1 蛋白) expression suggesting that MCT (显示 MCAT 蛋白) plays an important role in pancreatic cancer angiogenesis and tumor growth via activating the angiopoietin-1 (显示 ANGPT1 蛋白) pathway.

  8. The targeting of MCT1 (显示 CMA1 蛋白) and PFKFB3 (显示 PFKFB3 蛋白) regulated cell proliferation.

  9. MCT1 (显示 CMA1 蛋白) expression associates with the SCC (显示 CYP11A1 蛋白) type and metastatic behavior of AC, whereas MCT4 (显示 SLC16A4 蛋白) expression concomitantly increases from in situ SCC (显示 CYP11A1 蛋白) to invasive SCC (显示 CYP11A1 蛋白) and is significantly associated with the AC type. Consistently, FOXM1 (显示 FOXM1 蛋白) expression is statistically associated with MCT1 (显示 CMA1 蛋白) positivity in SCC (显示 CYP11A1 蛋白), whereas the expression of FOXO3a (显示 FOXO3 蛋白), a FOXM1 (显示 FOXM1 蛋白) functional antagonist, is linked to MCT1 (显示 CMA1 蛋白) negativity

  10. This study investigated MCT1 (显示 CMA1 蛋白) protein abundance in various human intestinal tissues.

Zebrafish Malignant T Cell Amplified Sequence 1 (MCTS1) interaction partners

  1. Data indicate that monocarboxylate transporters (MCTs1-4) were all found to be expressed in brains of embryos, and were localized in both neurons and astrocyte.

Cow (Bovine) Malignant T Cell Amplified Sequence 1 (MCTS1) interaction partners

  1. This study confirmed age-dependent changes of MCT1 expression in the rumen epithelium of newborn calves and showed that its expression might be affected by liquid feed type.

  2. These findings show that MCT 1 increases with the development of rumen function and also in adult animals MCT 1 may change with the feeding.

  3. The expression and distribution of monocarboxylate transporter 1 along the gastrointestinal tract of calves suggest it may play a role in transport of short chain fatty acids and their metabolites.

  4. The results show that monocarboxylate transporter 1 (MCT1) is a major route for short chain fatty acids (SCFA) efflux across the basolateral membrane of bovine large intestine and that it could play a role in the regulation of intracellular pH.

Pig (Porcine) Malignant T Cell Amplified Sequence 1 (MCTS1) interaction partners

  1. Data suggest that expression of MCT1 in intestinal mucosa can be altered by diet; here, expression of MCT1 is down-regulated in colonic mucosa by high-protein diet and appears to be linked to fermentation of dietary proteins by intestinal microbes.

  2. MCT1-mRNA showed a higher expression in the ileum; feeding inulin-coated butyrate resulted in an increased ileal surface; delivery of butyrate to the colon requires a more resistant inulin-coating.

蛋白简介Malignant T Cell Amplified Sequence 1 (MCTS1)

蛋白简介

The protein encoded by this gene is a proton-linked monocarboxylate transporter that catalyzes the movement of many monocarboxylates, such as lactate and pyruvate, across the plasma membrane. Mutations in this gene are associated with erythrocyte lactate transporter defect. Alternatively spliced transcript variants have been found for this gene.

Gene names and symbols associated with MCTS1

  • modifier of curly tail 1 (mct1)
  • malignant T cell amplified sequence 1 (TEgg094c21.2)
  • malignant T cell amplified sequence 1 (MCTS1)
  • malignant T cell amplified sequence 1 (mcts1)
  • malignant T cell amplified sequence 1 (Mcts1)
  • malignant T cell amplified sequence 1 (mcts1-a)
  • monocarboxylate transporter 1 (MCT1)
  • solute carrier family 16 (monocarboxylate transporter), member 1 (SLC16A1)
  • solute carrier family 16 (monocarboxylate transporter), member 1 (Slc16a1)
  • solute carrier family 16 (monocarboxylic acid transporters), member 1 (Slc16a1)
  • solute carrier family 16 (monocarboxylic acid transporters), member 1 (slc16a1)
  • solute carrier family 16, member 1 (monocarboxylic acid transporter 1) (SLC16A1)
  • 1500019M23Rik 蛋白
  • AL022710 蛋白
  • cb517 蛋白
  • HHF7 蛋白
  • MCT 蛋白
  • mct-1 蛋白
  • MCT-1A 蛋白
  • Mct1 蛋白
  • MCT1a 蛋白
  • MCTS1 蛋白
  • MGC89874 蛋白
  • RATMCT1 蛋白
  • RNMCT1 蛋白
  • zgc:55682 蛋白
  • zgc:56242 蛋白

Protein level used designations for MCTS1

malignant T cell amplified sequence 1 , malignant T cell-amplified sequence 1 , malignant T-cell-amplified sequence 1 , multiple copies T-cell malignancies , multiple copies T-cell malignancies 1 , MCT-1 , Malignant T cell amplified sequence 1-A , malignant T cell-amplified sequence 1-A , malignant T-cell-amplified sequence 1-A , MCT 1 , monocarboxylate transporter 1 , solute carrier family 16 (monocarboxylic acid transporters), member 1 , solute carrier family 16 member 1 , solute carrier family 16, member 1 (monocarboxylic acid transporter 1) , solute carrier 16 (monocarboxylic acid transporter), member 1 , MCT1 , monocarboxylate transporter 1a

GENE ID SPECIES
17236 Mus musculus
448679 Xenopus (Silurana) tropicalis
465836 Pan troglodytes
696543 Macaca mulatta
100528791 Ictalurus punctatus
28985 Homo sapiens
68995 Mus musculus
394046 Danio rerio
503679 Xenopus laevis
422363 Gallus gallus
481038 Canis lupus familiaris
508412 Bos taurus
302500 Rattus norvegicus
780423 Sus scrofa
6566 Homo sapiens
25027 Rattus norvegicus
20501 Mus musculus
368274 Danio rerio
475856 Canis lupus familiaris
505775 Bos taurus
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