anti-Male Germ Cell-Associated Kinase (MAK) 抗体

The product of MAK is a serine/threonine protein kinase related to kinases involved in cell cycle regulation. 再加上,我们可以发MAK 试剂盒 (7)MAK 蛋白 (7)和数多这个蛋白质的别的产品。

列出全部抗体 基因 基因ID UniProt
MAK 116904  
MAK 4117 P20794
MAK 25677 P20793

antibodies-online.cn销售最多的anti-MAK 抗体

Showing 10 out of 111 products:

产品编号 适用 宿主 标记 应用范围 图像 规格 供应商 交付 价格 详细
Cow 非结合性 IHC, WB WB Suggested Anti-MAK Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:312500Positive Control: Hela cell lysate 100 μL Log in to see 24至29个工作日
¥3,074.65
详细
非结合性 ELISA, WB Western blot analysis of extracts from HepG2 cells treated with PMA 125ng/ml 30', using MAK (Phospho-Tyr159) Antibody. The lane on the right is treated with the synthesized peptide. 100 μg Log in to see 24至29个工作日
¥3,026.87
详细
非结合性 EIA, IHC (p), WB Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. Western blot analysis of MAK (arrow) using MAK Antibody 0.4 mL Log in to see 29至35个工作日
¥4,086.26
详细
非结合性 IHC (p), WB Western blot analysis of MAK (arrow) using MAK Antibody (C-term) (ABIN391782). 293 cell lysates (2 µg/lane) either nontransfected (Lane 1) or transiently transfected with the MAK gene (Lane 2) (Origene Technologies). Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. BC = breast carcinoma. HC = hepatocarcinoma 400 μL Log in to see 5至8个工作日
¥2,325.14
详细
非结合性 ELISA, WB Western blot analysis of extracts from K562 cells, using MAK (Ab-159) Antibody. The lane on the right is treated with the synthesized peptide. 100 μg Log in to see 24至29个工作日
¥3,026.87
详细
非结合性 WB MAK Antibody (C-term) (ABIN1881520) western blot analysis in CEM cell line lysates (35 µg/lane). This demonstrates the MAK antibody detected the MAK protein (arrow). 400 μL Log in to see 32至37个工作日
¥2,875.04
详细
小鼠 非结合性 IF, WB Immunofluorescence of monoclonal antibody to MAK on HeLa cell (antibody concentration 10 µg/mL). Western Blot analysis of MAK expression in transfected 293T cell line by MAK monoclonal antibody (M02), clone 4E9. Lane 1: MAK transfected lysate(52.6 KDa). Lane 2: Non-transfected lysate. 0.1 mg Log in to see 11至15个工作日
¥3,179.71
详细
非结合性 IF (p), IHC (p) Formalin-fixed and paraffin embedded rat testis tissue labeled with Rabbit Anti-MAK Polyclonal Antibody, Unconjugated (ABIN2559543) at 1:200 followed by conjugation to the secondary antibody and DAB staining Formalin-fixed and paraffin embedded rat testis labeled with Anti-MAK Polyclonal Antibody, Unconjugated  at 1:200 followed by conjugation to the secondary antibody and DAB staining. 100 μL Log in to see 5至7个工作日
¥2,610.23
详细
非结合性 IF (p), IHC (p) Formalin-fixed and paraffin embedded rat testis tissue labeled with Rabbit Anti-MAK (Tyr159) Polyclonal Antibody, Unconjugated (ABIN2559531) at 1:200 followed by conjugation to the secondary antibody and DAB staining Formalin-fixed and paraffin embedded human prostate labeled with Anti-MAK (Tyr159) Polyclonal Antibody, Unconjugated  at 1:200 followed by conjugation to the secondary antibody and DAB staining. 100 μL Log in to see 5至7个工作日
¥2,799.40
详细
非结合性 WB 50 μg Log in to see 29至35个工作日
¥5,538.93
详细

通过反应活性、应用领域、克隆类型和共轭标记 MAK 抗体

特性 应用范围 宿主 克隆类型 标记
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引用最多的anti-MAK 抗体

  1. Human Polyclonal MAK Primary Antibody for WB - ABIN1881520 : Ma, Xia, Desai, Boucher, Guan, Shih, Shi, deVere White, Chen, Tepper, Kung: Male germ cell-associated kinase, a male-specific kinase regulated by androgen, is a coactivator of androgen receptor in prostate cancer cells. in Cancer research 2006 (PubMed)
    Show all 5 references for 1881520

  2. Human Monoclonal MAK Primary Antibody for IF, WB - ABIN393408 : Fu, Larson, Chitta, Parker, Turk, Lawrence, Kaldis, Galaktionov, Cohn, Shabanowitz, Hunt, Sturgill: Identification of yin-yang regulators and a phosphorylation consensus for male germ cell-associated kinase (MAK)-related kinase. in Molecular and cellular biology 2006 (PubMed)
    Show all 5 references for 393408

  3. Human Polyclonal MAK Primary Antibody for IHC (p), WB - ABIN391782 : Xia, Robinson, Ma, Chen, Wu, Qiu, Kung: Identification of human male germ cell-associated kinase, a kinase transcriptionally activated by androgen in prostate cancer cells. in The Journal of biological chemistry 2002 (PubMed)
    Show all 4 references for 391782

  4. Human Polyclonal MAK Primary Antibody for ELISA, WB - ABIN1533086 : Mungall, Palmer, Sims, Edwards, Ashurst, Wilming, Jones, Horton, Hunt, Scott, Gilbert, Clamp, Bethel, Milne, Ainscough, Almeida, Ambrose, Andrews, Ashwell, Babbage, Bagguley, Bailey, Banerjee, Barker et al.: The DNA sequence and analysis of human chromosome 6. ... in Nature 2003 (PubMed)
    Show all 2 references for 1533086

  5. Human Polyclonal MAK Primary Antibody for EIA, IHC (p) - ABIN359695 : Woodle, Newman, Cohen: Sterically stabilized liposomes: physical and biological properties. in Journal of drug targeting 1995 (PubMed)
    Show all 2 references for 359695

  6. Human Polyclonal MAK Primary Antibody for ELISA, WB - ABIN1532053 : Greenman, Stephens, Smith, Dalgliesh, Hunter, Bignell, Davies, Teague, Butler, Stevens, Edkins, OMeara, Vastrik, Schmidt, Avis, Barthorpe, Bhamra, Buck, Choudhury, Clements, Cole, Dicks, Forbes, Gray et al.: Patterns of somatic mutation in human cancer genomes. ... in Nature 2007 (PubMed)
    Show all 2 references for 1532053

更多抗MAK的相互作用对抗体

Mouse (Murine) Male Germ Cell-Associated Kinase (MAK) interaction partners

  1. the expressions of ICK/MAK/MOK proteins in the intestinal tract can be differentially and dynamically regulated, implicating a significant functional diversity within this group of protein kinases.

  2. Cardiomyopathy developed in mice deficient for alpha-kinase 3 (ALPK3 (显示 ALPK3 抗体))

  3. Results suggest that Mak is essential for the regulation of ciliary length and is required for the long-term survival of photoreceptors.

  4. data show that function of MAK is not essential for spermatogenesis and male fertility.

Human Male Germ Cell-Associated Kinase (MAK) interaction partners

  1. We identified the MAK and DHDDS (显示 DHDDS 抗体) mutations homozygously in only 2.1% and 0.8%, respectively, of patients of mixed ethnicity, but in 25.7% and 8.6%, respectively, of cases reporting Jewish ancestry

  2. Nonsense and missense mutations in MAK give rise to a non-syndromic recessive RP phenotype without apparent extra-ocular features.

  3. the expressions of ICK/MAK/MOK (显示 MOK 抗体) proteins in the intestinal tract can be differentially and dynamically regulated, implicating a significant functional diversity within this group of protein kinases.

  4. In glioblastoma cells with deregulated high levels of CCRK (显示 CDK20 抗体), its depletion restores cilia through ICK (显示 ICK 抗体) and an ICK (显示 ICK 抗体)-related kinase MAK, thereby inhibiting glioblastoma cell proliferation.

  5. these data implicate MAK in both adrogen receptor activation and chromosomal instability, acting in both early and late prostate cancer development.

  6. The patterns of disease expression in the MAK form of arRP showed some resemblance to patterns described in autosomal dominant RP, especially the form caused by RP1 (显示 STK19 抗体) mutations.

  7. Exome sequencing to identify a homozygous Alu insertion in exon 9 of male germ cell-associated kinase (MAK) as the cause of disease in an isolated individual with retinitis pigmentosa.

  8. Exome sequencing combined with this approach identified a homozygous nonsense mutation in male germ cell-associated kinase (MAK) in the single affected member of a consanguineous Turkish family with retinitis pigmentosa.

  9. MAK plays a general role in androgen receptor(AR (显示 AR 抗体)) function in prostate cancer cells and is likely to be a general coactivator of AR in prostate tissues.

  10. MRK (显示 ICK 抗体) phosphorylates Scythe (显示 BAT3 抗体) at T1080 in vitro as determined by site-directed mutagenesis and mass spectrometry, supporting the consensus and suggesting Scythe (显示 BAT3 抗体) as a physiological substrate for MRK (显示 ICK 抗体).

MAK 抗原简介

蛋白简介

The product of this gene is a serine/threonine protein kinase related to kinases involved in cell cycle regulation. It is expressed almost exclusively in the testis, primarily in germ cells. Studies of the mouse and rat homologs have localized the kinase to the chromosomes during meiosis in spermatogenesis, specifically to the synaptonemal complex that exists while homologous chromosomes are paired. There is, however, a study of the mouse homolog that has identified high levels of expression in developing sensory epithelia so its function may be more generalized. Three transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with MAK

  • male germ cell-associated kinase (MAK) 抗体
  • male germ cell-associated kinase (mak) 抗体
  • male germ cell-associated kinase (LOC100357745) 抗体
  • alpha-kinase 3 (Alpk3) 抗体
  • male germ cell-associated kinase (Mak) 抗体
  • A930010O05Rik 抗体
  • AW319487 抗体
  • D330016D04 抗体
  • dJ417M14.2 抗体
  • fj04c02 抗体
  • Ick 抗体
  • MAK 抗体
  • MGC82717 抗体
  • MGC146434 抗体
  • Midori 抗体
  • mKIAA1330 抗体
  • RP62 抗体
  • wu:fj04c02 抗体
  • xmak 抗体
  • zgc:56603 抗体

Protein level used designations for MAK

male germ cell-associated kinase , serine/threonine-protein kinase MAK-like , alpha-protein kinase 3 , myocyte induction differentiation originator , myocytic induction/differentiation originator , male germ cell-associated kinase retinal-enriched isoform , serine/threonine protein kinase MAK , serine/threonine-protein kinase MAK , protein kinase RCK , intestinal cell kinase

GENE ID SPECIES
420859 Gallus gallus
447015 Xenopus laevis
698353 Macaca mulatta
746604 Pan troglodytes
780268 Xenopus (Silurana) tropicalis
100019665 Monodelphis domestica
100051342 Equus caballus
100082794 Ornithorhynchus anatinus
100357745 Oryctolagus cuniculus
100469313 Ailuropoda melanoleuca
100603418 Nomascus leucogenys
116904 Mus musculus
4117 Homo sapiens
478721 Canis lupus familiaris
536048 Bos taurus
25677 Rattus norvegicus
17152 Mus musculus
335339 Danio rerio
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