Malate Dehydrogenase 1, NAD (Soluble) 蛋白 (MDH1)

Malate dehydrogenase catalyzes the reversible oxidation of malate to oxaloacetate, utilizing the NAD/NADH cofactor system in the citric acid cycle. 再加上,我们可以发Malate Dehydrogenase 1, NAD (Soluble) 抗体 (121)Malate Dehydrogenase 1, NAD (Soluble) 试剂盒 (11)和数多这个蛋白质的别的产品。

列出全部蛋白 基因 基因ID UniProt
MDH1 4190 P40925
MDH1 17449 P14152
MDH1 24551 O88989
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MDH1 蛋白 by Origin and Source

Origin 在表达 标记
Human , ,
, ,
Mouse (Murine)

Rat (Rattus) ,

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Fruit Fly (Drosophila melanogaster) Malate Dehydrogenase 1, NAD (Soluble) (MDH1) interaction partners

  1. Observations on Mdh1 in both Gpdh (显示 GPD1 蛋白) and Adh (显示 AVP 蛋白) backgrounds demonstrate significant increases in ethanol tolerance with partial reductions (50%) in cytosolic MDH (显示 MDH 蛋白) activity.

Pig (Porcine) Malate Dehydrogenase 1, NAD (Soluble) (MDH1) interaction partners

  1. Structural features of the alphaB-crystallin (显示 CRYAB 蛋白) oligomer when complexed with target proteins under mild stress conditions, i.e., reduction of alpha-lactalbumin (显示 LALBA 蛋白) at 37 degrees C and malate dehydrogenase (显示 MDH 蛋白) when heated at 42 degrees C, were investigated.

  2. Both immunofluorescence and immunoelectron microscopy demonstrated cMDH at the plasma membrane of LLC-PK(1) cells.

Human Malate Dehydrogenase 1, NAD (Soluble) (MDH1) interaction partners

  1. Data show that in the endogenous readthrough of the human MDH1 stop codon, the stop codon can encode tryptophan and arginine, and is tissue-specific.

  2. Proliferating cells rely on both MDH1 and LDH to replenish cytosolic NAD.

  3. Arginine methylation of MDH1 by CARM1 regulates cellular redox homeostasis and suppresses glutamine metabolism of pancreatic cancer.

  4. adipogenic differentiation may be regulated by the acetylation of MDH1

  5. The MDH1 gene is not the cause of RP28 (显示 FAM161A 蛋白)-linked autosomal recessive retinitis pigmentosa.

  6. expression of MDH1 is maintained in the adult heart but is not present in levels as high as in the fetus

  7. Malate Dehydrogenase (显示 ME1 蛋白) directly regulates the Tumor Suppressor Protein p53 (显示 TP53 蛋白)-dependent apoptosis upon glucose deprivation and involved in maintaining cellular metabolic state and further determining cell death.

Mouse (Murine) Malate Dehydrogenase 1, NAD (Soluble) (MDH1) interaction partners

  1. These findings provide strong evidence that MDH1 plays a critical role in osteoclast differentiation and function via modulation of the intracellular energy status, which might affect AMPK (显示 PRKAA1 蛋白) activity and NFATc1 (显示 NFATC1 蛋白) expression.

  2. adipogenic differentiation may be regulated by the acetylation of MDH1

  3. Mor2 is an essential factor for oocyte maturation and embryo development in mouse.

蛋白简介Malate Dehydrogenase 1, NAD (Soluble) (MDH1)

蛋白简介

Malate dehydrogenase catalyzes the reversible oxidation of malate to oxaloacetate, utilizing the NAD/NADH cofactor system in the citric acid cycle. The protein encoded by this gene is localized to the cytoplasm and may play pivotal roles in the malate-aspartate shuttle that operates in the metabolic coordination between cytosol and mitochondria. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.

Gene names and symbols associated with MDH1

  • malate dehydrogenase 5 (mdh5)
  • malate dehydrogenase, cytoplasmic (LOC100280767)
  • Malate dehydrogenase 1 (Mdh1)
  • malate dehydrogenase 1 (MDH1)
  • malate dehydrogenase 1, NAD (soluble) (Mdh1)
  • malate dehydrogenase 1 (Mdh1)
  • malate dehydrogenase 1 S homeolog (mdh1.S)
  • B230377B03Rik 蛋白
  • cMdh 蛋白
  • D17921 蛋白
  • Mdh 蛋白
  • Mdh-1 蛋白
  • mdh-s 蛋白
  • Mdh2 蛋白
  • mdha 蛋白
  • MdhD 蛋白
  • Mdhl 蛋白
  • MDL1 蛋白
  • MGC:1375 蛋白
  • Mor-2 蛋白
  • mor2 蛋白
  • sMdh 蛋白

Protein level used designations for MDH1

CL1892_2 , CL1892_2(431) , CL1892_2_ov , CL1892_2d , GRMZM2G415359 , IDP2139 , csu249 , csu580 , csu580b(mdh) , csu77b(mdh) , csuh00580 , csuh249 , cytoplasmic malate dehydrogenase , malate dehydrogenase, cytoplasmic , malate dehydrogenase4 , sMdh2 , sc154 , cytosolic malate dehydrogenase , diiodophenylpyruvate reductase , soluble malate dehydrogenase , malate dehydrogenase, soluble , Malate dehydrogenase-like enzyme

GENE ID SPECIES
542598 Zea mays
100280767 Zea mays
5656948 Drosophila melanogaster
396894 Sus scrofa
421281 Gallus gallus
4190 Homo sapiens
535182 Bos taurus
17449 Mus musculus
24551 Rattus norvegicus
474614 Canis lupus familiaris
493924 Felis catus
398872 Xenopus laevis
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