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MVP encodes the major component of the vault complex. 再加上，我们可以发Major Vault Protein 试剂盒 (33) 和 Major Vault Protein 蛋白 (10)和数多这个蛋白质的别的产品。
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Cow (Bovine) Monoclonal MVP Primary Antibody for IF, IP - ABIN968013
Kickhoefer, Rome: The sequence of a cDNA encoding the major vault protein from Rattus norvegicus. in Gene 1995
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Fish Polyclonal MVP Primary Antibody for IF (p), IHC (p) - ABIN671586
Hu, Peng, Li: The expression and significance of P-glycoprotein, lung resistance protein and multidrug resistance-associated protein in gastric cancer. in Journal of experimental & clinical cancer research : CR 2009
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Human Monoclonal MVP Primary Antibody for IF, IHC (p) - ABIN564285
Rahimi, Wilson, Saylor, Stelow, Thomas, Reibel, Levine, Shonka, Jameson, Read: p16, Cyclin D1, and HIF-1? Predict Outcomes of Patients with Oropharyngeal Squamous Cell Carcinoma Treated with Definitive Intensity-Modulated Radiation Therapy. in International journal of otolaryngology 2012
structure and cellular localization during embryonic development; findings indicate a dramatic relocalization of MVP from the cytoplasm to the nucleus during sea (显示 Slc25a1 抗体) urchin embryogenesis
Major vault protein is important in the drug resistance of cancer cells, but it requires the presence of vPARP (显示 PARP4 抗体) for full activity
Study found significant upregulation of MVP and BCRP (显示 ABCG2 抗体) whereas MRP1 (显示 MDM4 抗体) and UGT1A4 (显示 UGT1A4 抗体) were unaltered in drug resistant epilepsy brains. While upregulation of BCRP (显示 ABCG2 抗体) was significantly higher in mesial temporal lobe epilepsy (9.34+/-0.45; p<0.05), upregulation of MVP was significantly higher in focal cortical dysplasia (2.94+/-0.65; p<0.01).
Taxus chinensis var.-mediated downregulation of MRP1 (显示 MDM4 抗体), MDR1 (显示 TBC1D9 抗体), and LRP (显示 RPSA 抗体) might contribute to the reversal of drug resistance in non-small cell lung cancer stem cells.
We believe that for the first time, genetic variants at XRCC6 (显示 XRCC6 抗体) and MVP genes are associated with risk of more aggressive disease, and would be taken into account when assessing the malignancy of prostate cancer
MVP genetic polymorphisms and haplotypes may not be associated with drug resistance of partial epilepsy in the Chinese Han population.
NSCLCs [ non-small cell lung cancer ] expressing P-gp (显示 ABCB4 抗体) [P-glycoprotein ]/LRP (显示 RPSA 抗体) [ lung resistance-related protein] bear the EGFR (显示 EGFR 抗体) [epidermal growth factor receptor (显示 EGFR 抗体)] mutation in exon 19 or 21 easily.
The association of MVP amplification and PTEN (显示 PTEN 抗体) deletion could be a potential biomarker in glioblastoma.
Bag3 (显示 BAG3 抗体)-MVP is an important complex that regulates a potent prosurvival signaling pathway and contributes to chemotherapy resistance in breast cancer
LDL increases ABCB1 (显示 ABCB1 抗体), ABCC1 (显示 ABCC1 抗体), and LRP (显示 RPSA 抗体) expression in a human doxorubicin-resistant uterine sarcoma cell line.
Study demonstrates that vaults have a tumour-promoting potential by stabilizing EGFR (显示 EGFR 抗体)/PI3K (显示 PIK3CA 抗体)-mediated migration and survival pathways in human glioblastoma.
MVP may fine-tune SR-A (显示 MSR1 抗体) activity in macrophages which contributes to the development of atherosclerosis
MVP is hijacked by L. monocytogenes in order to counteract the autophagy process, a finding that could have major implications in deciphering the cellular role of vault particles.
These results suggest that up-regulation of MVP in multi-drug resistance (MDR) may involve chromatin remodeling.
Results suggest that major vault protein functions as a novel scaffold protein (显示 HOMER1 抗体) for both SHP-2 (显示 PTPN11 抗体) and Erk (显示 EPHB2 抗体).
results suggest that MVP makes a substantial contribution to epithelial cell-mediated resistance to infection
The crystal structure of the vault particle solved at 8 A resolution, together with the 2.1-A structure of the seven N-terminal domains (R1-R7) of MVP, provide an explanation for a reversible dissociation induced by low pH.
MVP is beneficial for functional recovery and axonal regrowth after spinal cord injury in adult zebrafish.
This gene encodes the major component of the vault complex. Vaults are multi-subunit ribonucleoprotein structures that may be involved in nucleo-cytoplasmic transport. The encoded protein may play a role in multiple cellular processes by regulating the MAP kinase, JAK/STAT and phosphoinositide 3-kinase/Akt signaling pathways. The encoded protein also plays a role in multidrug resistance, and expression of this gene may be a prognostic marker for several types of cancer. Alternatively spliced transcript variants have been observed for this gene.
major vault protein
, major vault protein-alpha
, major vault protein B
, lung resistance-related protein
, lung resistance-associated protein
, protein tyrosine phosphatase alpha
, protein-tyrosine phosphatase alpha
, receptor-type tyrosine-protein phosphatase alpha