Major Histocompatibility Complex, Class II, DM alpha (HLA-DMA) ELISA试剂盒

HLA-DMA belongs to the HLA class II alpha chain paralogues. 再加上,我们可以发Major Histocompatibility Complex, Class II, DM alpha 抗体 (78)Major Histocompatibility Complex, Class II, DM alpha 蛋白 (3)和数多这个蛋白质的别的产品。

list all ELISA KIts 基因 基因ID
大鼠 HLA-DMA HLA-DMA 294274
小鼠 HLA-DMA HLA-DMA 14998
HLA-DMA 3108

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Human Major Histocompatibility Complex, Class II, DM alpha (HLA-DMA) interaction partners

  1. DMA*01:01 (69.35%) and DMB*01:01 (52.5%) alleles were more frequent in Chinese Hans

  2. HLA DMA and DMB show no association with rheumatoid arthritis in US Caucasians.

  3. The results suggest that HLA-DMA*0104 may represent a novel allele of susceptibility to systemic lupus erythematosus.

  4. HLA-DMA may play an important role in pathogenesis of type 1 diabetes, and clinical status heterogeneity of type 1 diabetes may be related to genetic mechanism.

  5. The absence of HLA-DR/DM interactions at the limiting membrane prevents local loading of MHC class II molecules in phagosomes

  6. glycosylation promotes, but is not essential for, DMalphabeta ER exit; single DMalpha chains cannot fully oxidize without DMbeta (显示 GPHb5 ELISA试剂盒), while DMbeta (显示 GPHb5 ELISA试剂盒) forms disulfide-linked homodimers without DMalpha

Major Histocompatibility Complex, Class II, DM alpha (HLA-DMA) 抗原简介

Antigen Summary

HLA-DMA belongs to the HLA class II alpha chain paralogues. This class II molecule is a heterodimer consisting of an alpha (DMA) and a beta chain (DMB), both anchored in the membrane. It is located in intracellular vesicles. DM plays a central role in the peptide loading of MHC class II molecules by helping to release the CLIP molecule from the peptide binding site. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). The alpha chain is approximately 33-35 kDa and its gene contains 5 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, exon 4 encodes the transmembrane domain and the cytoplasmic tail.

Gene names and symbols associated with HLA-DMA

  • RT1 class II, locus DMa (RT1-DMa) 抗体
  • SLA-DM alpha chain (SLA-DMA) 抗体
  • major histocompatibility complex, class II, DM alpha (HLA-DMA) 抗体
  • histocompatibility 2, class II, locus DMa (H2-DMa) 抗体
  • D6S222E 抗体
  • DMA 抗体
  • H-2Ma 抗体
  • H2-Ma 抗体
  • HLA-DMA 抗体
  • HLADM 抗体
  • RING6 抗体
  • RT1.DMa 抗体
  • RT1.Ma 抗体

Protein level used designations for HLA-DMA

RT1 class II, DM alpha , MHC class II-like alpha chain , major histocompatibility complex, class II, DM alpha , H2-M alpha , class II histocompatibility antigen, M alpha chain , histocompatibility 2, class II, locus Ma , HLA class II histocompatibility antigen, DM alpha chain , MHC class II antigen DMA , really interesting new gene 6 protein

GENE ID SPECIES
294274 Rattus norvegicus
445528 Sus scrofa
481732 Canis lupus familiaris
14998 Mus musculus
3108 Homo sapiens
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