anti-Major Histocompatibility Complex, Class II, DM alpha (HLA-DMA) 抗体

HLA-DMA belongs to the HLA class II alpha chain paralogues. 再加上,我们可以发Major Histocompatibility Complex, Class II, DM alpha 蛋白 (3)Major Histocompatibility Complex, Class II, DM alpha 试剂盒 (2)和数多这个蛋白质的别的产品。

列出全部抗体 基因 基因ID
HLA-DMA 294274
HLA-DMA 14998
HLA-DMA 3108

antibodies-online.cn销售最多的anti-Major Histocompatibility Complex, Class II, DM alpha 抗体

Showing 10 out of 78 products:

产品编号 适用 宿主 标记 应用范围 图像 规格 供应商 交付 价格 详细
非结合性 WB 50 μg Log in to see 29至35个工作日
¥5,538.93
详细
非结合性 WB WB Suggested Anti-HLA-DMA AntibodyTitration: 1.0 µg/mL  Positive Control: MCF7 Whole Cell 100 μL Log in to see 24至29个工作日
¥3,074.65
详细
小鼠 大鼠 非结合性 Func, IHC (fro), FACS, IHC (p), IP, WB   0.1 mg Log in to see 29至35个工作日
¥2,371.04
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小鼠 大鼠 FITC FACS   0.1 mg Log in to see 29至35个工作日
¥2,673.68
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小鼠 非结合性 WB HLA-DMA monoclonal antibody (M01), clone 3F12-F11 Western Blot analysis of HLA-DMA expression in U-2 OS on formalin-fixed paraffin-embedded human malignant lymphoma, diffuse large B tissue (antibody concentration 3 µg/mL). 0.1 mg Log in to see 11至15个工作日
¥3,179.71
详细
小鼠 非结合性 IHC (p), ELISA, WB 100 μg Log in to see 29至35个工作日
¥5,401.63
详细
小鼠 非结合性 FACS, ICC, IF, IHC, IHC (p), WB Immunocytochemistry/Immunofluorescence: HLA DMA Antibody (5C9NB) [NBP2-44300] - Daudi cells were fixed for 10 minutes using 10% formalin and then permeabilized for 5 minutes using 1X TBS + 0.5% Triton-X100. The cells were incubated with MHC Class II (5C9NB) at a 1:40 dilution for 1 hour at room temperature and detected with Dylight 488 (Green). Actin was detected using Phalloidin 568 (Red). Nuclei were detected using DAPI (Blue). Cells were imaged using a 40X objective. Flow (Cell Surface): HLA DMA Antibody (5C9NB) [NBP2-44300] - Analysis using the Azide Free version of NBP2-44300. Detection of Human PBMC cells (surface) with HLA DMA (5C9NB) antibody (red) or isotype control (mouse IgG1; green). Blue line represents cells alone. Positive staining was observed using PE conjugated mouse anti-IgG(H+L) secondary antibody. Live cells were gated (FL-2) for analysis. 0.1 mg Log in to see 25至31个工作日
¥2,594.28
详细
非结合性 WB Western Blot: HLA DMA Antibody [NBP1-74130] - Titration: 1.0 ug/ml Positive Control: MCF7 Whole Cell. 100 μL Log in to see 26至33个工作日
¥3,655.56
详细
非结合性 IHC, WB Western blot analysis of extracts of various cell lines, using HLA-DMA antibody. 100 μL Log in to see 34至38个工作日
¥2,882.69
详细
非结合性 IP, WB HLA-DMA MaxPab rabbit polyclonal antibody. Western Blot analysis of HLA-DMA expression in mouse kidney. HLA-DMA MaxPab rabbit polyclonal antibody. Western Blot analysis of HLA-DMA expression in HeLa. 100 μL Log in to see 29至34个工作日
¥3,073.67
详细

通过反应活性、应用领域、克隆类型和共轭标记 HLA-DMA 抗体

特性 应用范围 宿主 克隆类型 标记
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引用最多的anti-Major Histocompatibility Complex, Class II, DM alpha 抗体

  1. Mouse (Murine) Monoclonal HLA-DMA Primary Antibody for FACS - ABIN1107565 : Bhattacharya, Dorf, Springer: A shared alloantigenic determinant on Ia antigens encoded by the I-A and I-E subregions: evidence for I region gene duplication. in Journal of immunology (Baltimore, Md. : 1950) 1982 (PubMed)
    Show all 8 references for 1107565

  2. Mouse (Murine) Monoclonal HLA-DMA Primary Antibody for Func, IHC (fro) - ABIN1107564 : Kuwano, Prazma, Yazawa, Watanabe, Ishiura, Kumanogoh, Okochi, Tamaki, Fujimoto, Tedder: CD83 influences cell-surface MHC class II expression on B cells and other antigen-presenting cells. in International immunology 2007 (PubMed)
    Show all 8 references for 1107564

  3. Human Polyclonal HLA-DMA Primary Antibody for WB - ABIN611597 : Nagamine, Kudoh, Kawasaki, Minoshima, Asakawa, Ito, Shimizu: Genomic organization and complete nucleotide sequence of the TMEM1 gene on human chromosome 21q22.3. in Biochemical and biophysical research communications 1997 (PubMed)
    Show all 2 references for 611597

更多抗Major Histocompatibility Complex, Class II, DM alpha的相互作用对抗体

Human Major Histocompatibility Complex, Class II, DM alpha (HLA-DMA) interaction partners

  1. DMA*01:01 (69.35%) and DMB*01:01 (52.5%) alleles were more frequent in Chinese Hans

  2. HLA DMA and DMB show no association with rheumatoid arthritis in US Caucasians.

  3. The results suggest that HLA-DMA*0104 may represent a novel allele of susceptibility to systemic lupus erythematosus.

  4. HLA-DMA may play an important role in pathogenesis of type 1 diabetes, and clinical status heterogeneity of type 1 diabetes may be related to genetic mechanism.

  5. The absence of HLA-DR/DM interactions at the limiting membrane prevents local loading of MHC class II molecules in phagosomes

  6. glycosylation promotes, but is not essential for, DMalphabeta ER exit; single DMalpha chains cannot fully oxidize without DMbeta (显示 GPHb5 抗体), while DMbeta (显示 GPHb5 抗体) forms disulfide-linked homodimers without DMalpha

Major Histocompatibility Complex, Class II, DM alpha (HLA-DMA) 抗原简介

蛋白简介

HLA-DMA belongs to the HLA class II alpha chain paralogues. This class II molecule is a heterodimer consisting of an alpha (DMA) and a beta chain (DMB), both anchored in the membrane. It is located in intracellular vesicles. DM plays a central role in the peptide loading of MHC class II molecules by helping to release the CLIP molecule from the peptide binding site. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). The alpha chain is approximately 33-35 kDa and its gene contains 5 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, exon 4 encodes the transmembrane domain and the cytoplasmic tail.

Gene names and symbols associated with HLA-DMA

  • RT1 class II, locus DMa (RT1-DMa) 抗体
  • SLA-DM alpha chain (SLA-DMA) 抗体
  • major histocompatibility complex, class II, DM alpha (HLA-DMA) 抗体
  • histocompatibility 2, class II, locus DMa (H2-DMa) 抗体
  • D6S222E 抗体
  • DMA 抗体
  • H-2Ma 抗体
  • H2-Ma 抗体
  • HLA-DMA 抗体
  • HLADM 抗体
  • RING6 抗体
  • RT1.DMa 抗体
  • RT1.Ma 抗体

Protein level used designations for HLA-DMA

RT1 class II, DM alpha , MHC class II-like alpha chain , major histocompatibility complex, class II, DM alpha , H2-M alpha , class II histocompatibility antigen, M alpha chain , histocompatibility 2, class II, locus Ma , HLA class II histocompatibility antigen, DM alpha chain , MHC class II antigen DMA , really interesting new gene 6 protein

GENE ID SPECIES
294274 Rattus norvegicus
445528 Sus scrofa
481732 Canis lupus familiaris
14998 Mus musculus
3108 Homo sapiens
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